3257 CDBP03256 Taste receptor type 2 member 4 Q9NYW5 TA2R4_HUMAN false false Receptor Homo_sapiens TAS2R4 299 33840.2 10.28 Involved in G-protein coupled receptor activity Gustducin-coupled receptor for denatonium and N(6)- propyl-2-thiouracil implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. In airway epithelial cells, binding of denatonium increases the intracellular calcium ion concentration and stimulates ciliary beat frequency ["None"] ["10-30", "47-67", "82-102", "132-152", "173-193", "231-251", "263-283"] AC004979 41393516 TAS2R4 Chromosome:7 7q31.3-q32 TAS2R4 HGNC:14911 true 2020-06-12T23:07:12Z 2020-07-28T02:28:37Z 1 0 0