Showing Protein Taste receptor type 2 member 40 (CDBP03254)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 15 compounds
Identification
HMDB Protein ID CDBP03254
Secondary Accession Numbers Not Available
Name Taste receptor type 2 member 40
Description Not Available
Synonyms
  1. G-protein coupled receptor 60
  2. T2R40
  3. T2R58
  4. Taste receptor type 2 member 58
Gene Name TAS2R40
Protein Type Receptor
Biological Properties
General Function Involved in G-protein coupled receptor activity
Specific Function Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5
GO Classification
Component
cell part
membrane part
intrinsic to membrane
integral to membrane
Function
transmembrane receptor activity
molecular transducer activity
signal transducer activity
g-protein coupled receptor activity
receptor activity
Process
multicellular organismal process
system process
neurological system process
sensory perception
sensory perception of chemical stimulus
sensory perception of taste
signaling
signaling pathway
cell surface receptor linked signaling pathway
g-protein coupled receptor protein signaling pathway
Cellular Location
  1. Membrane
  2. Multi-pass membrane protein
Pathways
Gene Properties
Chromosome Location Chromosome:7
Locus 7q34
SNPs TAS2R40
Gene Sequence 
>972 bp
ATGGCAACGGTGAACACAGATGCCACAGATAAAGACATATCCAAGTTCAAGGTCACCTTC
ACTTTGGTGGTCTCCGGAATAGAGTGCATCACTGGCATCCTTGGGAGTGGCTTCATCACG
GCCATCTATGGGGCTGAGTGGGCCAGGGGCAAAACACTCCCCACTGGTGACCGCATTATG
TTGATGCTGAGCTTTTCCAGGCTCTTGCTACAGATTTGGATGATGCTGGAGAACATTTTC
AGTCTGCTATTCCGAATTGTTTATAACCAAAACTCAGTGTATATCCTCTTCAAAGTCATC
ACTGTCTTTCTGAACCATTCCAATCTCTGGTTTGCTGCCTGGCTCAAAGTCTTCTATTGT
CTTAGAATTGCAAACTTCAATCATCCTTTGTTCTTCCTGATGAAGAGGAAAATCATAGTG
CTGATGCCTTGGCTTCTCAGGCTGTCAGTGTTGGTTTCCTTAAGCTTCAGCTTTCCTCTC
TCGAGAGATGTCTTCAATGTGTATGTGAATAGCTCCATTCCTATCCCCTCCTCCAACTCC
ACGGAGAAGAAGTACTTCTCTGAGACCAATATGGTCAACCTGGTATTTTTCTATAACATG
GGGATCTTCGTTCCTCTGATCATGTTCATCCTGGCAGCCACCCTGCTGATCCTCTCTCTC
AAGAGACACACCCTACACATGGGAAGCAATGCCACAGGGTCCAGGGACCCCAGCATGAAG
GCTCACATAGGGGCCATCAAAGCCACCAGCTACTTTCTCATCCTCTACATTTTCAATGCA
ATTGCTCTATTTCTTTCCACGTCCAACATCTTTGACACTTACAGTTCCTGGAATATTTTG
TGCAAGATCATCATGGCTGCCTACCCTGCCGGCCACTCAGTACAACTGATCTTGGGCAAC
CCTGGGCTGAGAAGAGCCTGGAAGCGGTTTCAGCACCAAGTTCCTCTTTACCTAAAAGGG
CAGACTCTGTGA
Protein Properties
Number of Residues 323
Molecular Weight 36811.4
Theoretical pI 10.43
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["15-35", "59-79", "101-121", "141-162", "191-211", "248-268", "277-297"]
Protein Sequence 
>Taste receptor type 2 member 40
MATVNTDATDKDISKFKVTFTLVVSGIECITGILGSGFITAIYGAEWARGKTLPTGDRIM
LMLSFSRLLLQIWMMLENIFSLLFRIVYNQNSVYILFKVITVFLNHSNLWFAAWLKVFYC
LRIANFNHPLFFLMKRKIIVLMPWLLRLSVLVSLSFSFPLSRDVFNVYVNSSIPIPSSNS
TEKKYFSETNMVNLVFFYNMGIFVPLIMFILAATLLILSLKRHTLHMGSNATGSRDPSMK
AHIGAIKATSYFLILYIFNAIALFLSTSNIFDTYSSWNILCKIIMAAYPAGHSVQLILGN
PGLRRAWKRFQHQVPLYLKGQTL
GenBank ID Protein 20336515
UniProtKB/Swiss-Prot ID P59535
UniProtKB/Swiss-Prot Entry Name T2R40_HUMAN
PDB IDs Not Available
GenBank Gene ID AF494229
GeneCard ID TAS2R40
GenAtlas ID TAS2R40
HGNC ID HGNC:18885
References
General References Not Available