Identification |
HMDB Protein ID
| CDBP03250 |
Secondary Accession Numbers
| Not Available |
Name
| Synaptotagmin-like protein 3 |
Description
| Not Available |
Synonyms
|
- Exophilin-6
|
Gene Name
| SYTL3 |
Protein Type
| Metal Binding |
Biological Properties |
General Function
| Involved in Rab GTPase binding |
Specific Function
| May act as Rab effector protein and play a role in vesicle trafficking. Binds phospholipids in the presence of calcium ions |
GO Classification
|
Function |
cation binding |
metal ion binding |
binding |
transition metal ion binding |
zinc ion binding |
enzyme regulator activity |
rab gtpase binding |
nucleoside-triphosphatase regulator activity |
gtpase regulator activity |
small gtpase regulator activity |
ion binding |
Process |
establishment of localization |
transport |
protein transport |
intracellular protein transport |
|
Cellular Location
|
- Endomembrane system
- Peripheral membrane protein
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:6 |
Locus
| 6q25.3 |
SNPs
| SYTL3 |
Gene Sequence
|
>1833 bp
ATGGCCCAAGAAATAGATCTGAGTGCTCTCAAGGAGTTAGAACGCGAGGCCATTCTCCAG
GTCCTGTACCGAGACCAGGCGGTTCAAAACACAGAGGAGGAGAGGACACGGAAACTGAAA
ACACACCTGCAGCATCTCCGGTGGAAAGGAGCGAAGAACACGGACTGGGAGCACAAAGAG
AAGTGCTGTGCGCGCTGCCAGCAGGTGCTGGGGTTCCTGCTGCACCGGGGCGCCGTGTGC
CGGGGCTGCAGCCACCGCGTGTGTGCCCAGTGCCGAGTGTTCCTGAGGGGGACCCATGCC
TGGAAGTGCACGGTGTGCTTCGAGGACAGGAATGTCAAAATAAAAACTGGAGAATGGTTC
TATGAGGAACGAGCCAAGAAATTTCCAACTGGAGGCAAACATGAGACAGTTGGAGGGCAG
CTCTTGCAATCTTATCAGAAGCTGAGCAAAATTTCTGTGGTTCCTCCTACTCCACCTCCT
GTCAGCGAGAGCCAGTGCAGCCGCAGTCCTGGCAGGTTACAGGAATTTGGTCAGTTTAGA
GGATTTAATAAGTCCGTGGAAAATTTGTTTCTGTCTCTTGCTACCCACGTGAAAAAGCTC
TCCAAATCCCAGAATGATATGACTTCTGAGAAGCATCTTCTCGCCACGGGCCCCAGGCAG
TGTGTGGGACAGACAGAGAGACGGAGCCAGTCTGACACTGCGGTCAACGTCACCACCAGG
AAGGTCAGTGCACCAGATATTCTGAAACCTCTCAATCAAGAGGATCCCAAATGCTCTACT
AACCCTATTTTGAAGCAACAGAATCTCCCATCCAGTCCGGCACCCAGTACCATATTCTCT
GGAGGTTTTAGACACGGAAGTTTAATTAGCATTGACAGCACCTGTACAGAGATGGGCAAT
TTTGACAATGCTAATGTCACTGGAGAAATAGAATTTGCCATTCATTATTGCTTCAAAACC
CATTCTTTAGAAATATGCATCAAGGCCTGTAAGAACCTTGCCTATGGAGAAGAAAAGAAG
AAAAAGTGCAATCCGTATGTGAAGACCTACCTGTTGCCCGACAGATCCTCCCAGGGAAAG
CGCAAGACTGGAGTCCAAAGGAACACCGTGGACCCGACCTTTCAGGAGACCTTGAAGTAT
CAGGTGGCCCCTGCCCAGCTGGTGACCCGGCAGCTGCAGGTCTCGGTGTGGCATCTGGGC
ACGCTGGCCCGGAGAGTGTTTCTTGGAGAAGTGATCATTCCTCTGGCCACGTGGGACTTT
GAAGACAGCACAACACAGTCCTTCCGCTGGCATCCGCTCCGGGCCAAGGCGGAGAAATAC
GAAGACAGCGTTCCTCAGAGTAATGGAGAGCTCACAGTCCGGGCTAAGCTGGTTCTCCCT
TCACGGCCCAGAAAACTCCAAGAGGCTCAAGAAGGGACAGATCAGCCATCACTTCATGGT
CAACTTTGTTTGGTAGTGCTAGGAGCCAAGAATTTACCTGTGCGGCCAGATGGCACCTTG
AACTCATTTGTTAAGGGCTGTCTCACTCTGCCAGACCAACAAAAACTGAGACTGAAGTCG
CCAGTCCTGAGGAAGCAGGCTTGCCCCCAGTGGAAACACTCATTTGTCTTCAGTGGCGTA
ACCCCAGCTCAGCTGAGGCAGTCAAGCTTGGAGTTAACTGTCTGGGATCAGGCCCTCTTT
GGAATGAACGACCGCTTGCTTGGAGGAACCAGACTTGGTTCAAAGGGAGACACAGCTGTT
GGCGGGGATGCATGCTCACTATCGAAGCTCCAGTGGCAGAAAGTCCTTTCCAGCCCCAAT
CTATGGACAGACATGACTCTTGTCCTGCACTGA
|
Protein Properties |
Number of Residues
| 610 |
Molecular Weight
| 68559.1 |
Theoretical pI
| 9.78 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Synaptotagmin-like protein 3
MAQEIDLSALKELEREAILQVLYRDQAVQNTEEERTRKLKTHLQHLRWKGAKNTDWEHKE
KCCARCQQVLGFLLHRGAVCRGCSHRVCAQCRVFLRGTHAWKCTVCFEDRNVKIKTGEWF
YEERAKKFPTGGKHETVGGQLLQSYQKLSKISVVPPTPPPVSESQCSRSPGRLQEFGQFR
GFNKSVENLFLSLATHVKKLSKSQNDMTSEKHLLATGPRQCVGQTERRSQSDTAVNVTTR
KVSAPDILKPLNQEDPKCSTNPILKQQNLPSSPAPSTIFSGGFRHGSLISIDSTCTEMGN
FDNANVTGEIEFAIHYCFKTHSLEICIKACKNLAYGEEKKKKCNPYVKTYLLPDRSSQGK
RKTGVQRNTVDPTFQETLKYQVAPAQLVTRQLQVSVWHLGTLARRVFLGEVIIPLATWDF
EDSTTQSFRWHPLRAKAEKYEDSVPQSNGELTVRAKLVLPSRPRKLQEAQEGTDQPSLHG
QLCLVVLGAKNLPVRPDGTLNSFVKGCLTLPDQQKLRLKSPVLRKQACPQWKHSFVFSGV
TPAQLRQSSLELTVWDQALFGMNDRLLGGTRLGSKGDTAVGGDACSLSKLQWQKVLSSPN
LWTDMTLVLH
|
External Links |
GenBank ID Protein
| 66347777 |
UniProtKB/Swiss-Prot ID
| Q4VX76 |
UniProtKB/Swiss-Prot Entry Name
| SYTL3_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| AL589931 |
GeneCard ID
| SYTL3 |
GenAtlas ID
| SYTL3 |
HGNC ID
| HGNC:15587 |
References |
General References
| Not Available |