Showing Protein Synaptotagmin-3 (CDBP03244)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 compounds
Identification
HMDB Protein ID CDBP03244
Secondary Accession Numbers Not Available
Name Synaptotagmin-3
Description Not Available
Synonyms
  1. Synaptotagmin III
  2. SytIII
Gene Name SYT3
Protein Type Transporter
Biological Properties
General Function Involved in transporter activity
Specific Function May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis
GO Classification
Component
cytoplasmic vesicle
cytoplasmic membrane-bounded vesicle
coated vesicle
clathrin-coated vesicle
synaptic vesicle
membrane
cell part
organelle
vesicle
Function
transporter activity
Process
establishment of localization
transport
Cellular Location
  1. Cytoplasmic vesicle
  2. Single-pass membrane protein
  3. secretory vesicle
  4. synaptic vesicle membrane
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 19q13.33
SNPs SYT3
Gene Sequence 
>1773 bp
ATGTCAGGAGACTACGAGGATGACCTCTGCCGGCGGGCACTCATCCTGGTCTCGGACCTC
TGTGCGCGGGTCCGAGATGCTGACACCAACGACAGGTGCCAGGAGTTCAATGACCGAATC
CGAGGCTATCCCCGGGGTCCAGATGCAGACATCTCCGTGAGCCTGCTGTCGGTCATCGTG
ACATTCTGTGGCATTGTCCTTCTGGGTGTCTCTCTCTTCGTGTCCTGGAAGTTGTGCTGG
GTGCCCTGGCGGGACAAGGGAGGCTCGGCAGTGGGCGGTGGCCCCCTGCGCAAAGACCTA
GGCCCTGGTGTCGGGCTGGCAGGCCTGGTAGGCGGAGGCGGGCACCACCTGGCGGCTGGC
CTGGGTGGCCATCCTCTGCTGGGCGGCCCACACCACCATGCCCATGCCGCCCACCATCCA
CCCTTTGCTGAGCTGCTGGAGCCAGGCAGCCTGGGGGGTTCTGACACCCCTGAGCCCTCC
TACTTGGACATGGACTCGTATCCAGAGGCTGCAGCAGCAGCAGTGGCCGCTGGGGTCAAA
CCGAGCCAAACATCCCCTGAGCTGCCCTCTGAGGGGGGAGCAGGCTCTGGGTTGCTCCTG
CTGCCCCCCAGTGGTGGGGGCTTGCCCAGTGCCCAGTCACATCAGCAGGTCACAAGCCTG
GCACCCACTACCAGGTACCCAGCCCTGCCCCGACCCCTCACCCAGCAGACTCTGACCTCC
CAGCCGGACCCCAGCAGTGAGGAGCGCCCACCTGCCCTGCCCTTACCCCTGCCTGGAGGC
GAGGAAAAAGCCAAACTCATTGGGCAGATTAAGCCAGAGCTGTACCAGGGGACTGGCCCT
GGTGGCCGGCGGAGCGGTGGGGGCCCAGGCTCTGGAGAGGCAGGCACAGGGGCACCCTGT
GGCCGTATCAGCTTCGCCCTGCGGTACCTCTATGGCTCGGACCAGCTGGTGGTGAGGATC
CTGCAGGCCCTGGACCTCCCTGCCAAGGACTCCAACGGCTTCTCAGACCCCTACGTCAAG
ATCTACCTGCTGCCTGACCGCAAGAAAAAGTTTCAGACCAAGGTGCACAGGAAGACCCTG
AACCCCGTCTTCAATGAGACGTTTCAATTCTCGGTGCCCCTGGCCGAGCTGGCCCAACGC
AAACTGCACTTCAGCGTCTATGACTTTGACCGCTTCTCGCGGCACGACCTCATCGGCCAG
GTGGTGCTGGACAACCTCCTGGAGCTGGCCGAGCAGCCCCCTGACCGCCCGCTCTGGAGG
GACATCGTGGAGGGCGGCTCGGAAAAAGCAGATCTTGGGGAGCTCAACTTCTCACTCTGC
TACCTCCCCACGGCCGGGCGCCTCACCGTGACCATCATCAAAGCCTCTAACCTCAAAGCG
ATGGACCTCACTGGCTTCTCAGACCCCTACGTGAAGGCCTCCCTGATCAGCGAGGGGCGG
CGTCTGAAGAAGCGGAAAACCTCCATCAAGAAGAACACGCTGAACCCCACCTATAATGAG
GCGCTGGTGTTCGACGTGGCCCCCGAGAGCGTGGAGAACGTGGGGCTCAGCATCGCCGTG
GTGGACTACGACTGCATCGGGCACAACGAGGTGATCGGCGTGTGCCGTGTGGGCCCCGAC
GCTGCCGACCCGCACGGCCGCGAGCACTGGGCAGAGATGCTGGCCAATCCCCGCAAGCCC
GTGGAGCACTGGCATCAGCTAGTGGAGGAAAAGACTGTGACCAGCTTCACAAAAGGCAGC
AAAGGACTATCAGAGAAAGAGAACTCCGAGTGA
Protein Properties
Number of Residues 590
Molecular Weight 63303.2
Theoretical pI 6.6
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["55-75"]
Protein Sequence 
>Synaptotagmin-3
MSGDYEDDLCRRALILVSDLCARVRDADTNDRCQEFNDRIRGYPRGPDADISVSLLSVIV
TFCGIVLLGVSLFVSWKLCWVPWRDKGGSAVGGGPLRKDLGPGVGLAGLVGGGGHHLAAG
LGGHPLLGGPHHHAHAAHHPPFAELLEPGSLGGSDTPEPSYLDMDSYPEAAAAAVAAGVK
PSQTSPELPSEGGAGSGLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLTS
QPDPSSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGTGAPC
GRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTL
NPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWR
DIVEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGR
RLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPD
AADPHGREHWAEMLANPRKPVEHWHQLVEEKTVTSFTKGSKGLSEKENSE
GenBank ID Protein 13276689
UniProtKB/Swiss-Prot ID Q9BQG1
UniProtKB/Swiss-Prot Entry Name SYT3_HUMAN
PDB IDs
GenBank Gene ID AL136594
GeneCard ID SYT3
GenAtlas ID SYT3
HGNC ID HGNC:11511
References
General References Not Available