Identification
HMDB Protein ID CDBP03240
Secondary Accession Numbers Not Available
Name Synaptotagmin-11
Description Not Available
Synonyms
  1. Synaptotagmin XI
  2. SytXI
Gene Name SYT11
Protein Type Transporter
Biological Properties
General Function Involved in transporter activity
Specific Function May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis
GO Classification
Component
cytoplasmic vesicle
cytoplasmic membrane-bounded vesicle
coated vesicle
clathrin-coated vesicle
synaptic vesicle
membrane
cell part
organelle
vesicle
Function
transporter activity
Process
establishment of localization
transport
Cellular Location
  1. Cytoplasmic vesicle
  2. Membrane
  3. Single-pass membrane protein
  4. Single-pass membrane protein
  5. secretory vesicle
  6. Cell junction
  7. synapse
  8. synaptic vesicle membrane
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 1q21.2
SNPs SYT11
Gene Sequence
>1296 bp
ATGGCTGAGATCACCAATATCCGACCTAGCTTTGATGTGTCACCGGTGGTGGCCGGCCTC
ATCGGGGCCTCTGTGCTGGTGGTGTGTGTCTCGGTGACCGTCTTTGTCTGGTCATGCTGC
CACCAGCAGGCAGAGAAGAAGCACAAGAGCCCACCATACAAGTTTATTCACATGCTCAAA
GGCATCAGCATATACCCAGAGACCCTCAGCAACAAGAAGAAAATCATCAAAGTGCGGAGA
GACAAAGATGGTCCTGGGAGGGAAGGTGGACGTAGGAACCTGTTGGTGGACGCAGCAGAG
GCTGGCCTGCTAAGCCGAGACAAAGATCCCAGGGGGCCTAGCTCTGGATCTTGTATAGAC
CAATTACCCATCAAAATGGACTATGGGGAAGAACTAAGGAGCCCTATTACAAGCCTGACC
CCTGGGGAGAGCAAAACCACCTCTCCATCATCTCCAGAGGAGGATGTCATGCTAGGATCC
CTCACCTTCTCAGTGGACTATAACTTCCCGAAAAAAGCCCTGGTGGTGACAATCCAGGAG
GCCCACGGGCTGCCAGTGATGGATGACCAGACCCAGGGATCTGACCCCTACATCAAAATG
ACCATCCTTCCTGACAAACGGCATCGGGTGAAGACCAGAGTGCTGCGGAAGACCCTGGAC
CCTGTGTTTGACGAGACCTTCACCTTCTATGGCATCCCCTACAGCCAGCTGCAGGACCTG
GTGCTGCACTTCCTTGTCCTCAGCTTTGACCGCTTCTCTCGGGATGATGTCATTGGCGAG
GTCATGGTGCCACTGGCAGGGGCGGACCCCAGCACAGGCAAGGTACAACTGACCAGGGAC
ATCATCAAAAGGAATATCCAGAAGTGCATCAGCAGAGGGGAGCTCCAGGTGTCTCTGTCA
TATCAGCCTGTGGCACAGAGAATGACAGTGGTGGTCCTCAAAGCCAGACACTTGCCGAAG
ATGGATATCACCGGTCTCTCAGGTAATCCTTATGTCAAGGTGAACGTCTACTACGGCAGA
AAGCGCATTGCCAAGAAGAAAACCCATGTGAAGAAGTGCACTTTGAACCCCATCTTCAAT
GAATCTTTCATCTACGACATCCCCACTGACCTCCTGCCTGATATCAGCATCGAGTTCCTC
GTTATCGACTTCGATCGCACCACCAAGAATGAGGTGGTGGGGAGGCTGATCCTGGGGGCA
CACAGTGTCACAGCCAGTGGTGCTGAACACTGGAGAGAGGTCTGCGAGAGCCCCCGCAAG
CCTGTGGCCAAGTGGCACAGTCTGAGCGAGTACTAA
Protein Properties
Number of Residues 431
Molecular Weight 48296.5
Theoretical pI 9.45
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["16-36"]
Protein Sequence
>Synaptotagmin-11
MAEITNIRPSFDVSPVVAGLIGASVLVVCVSVTVFVWSCCHQQAEKKQKNPPYKFIHMLK
GISIYPETLSNKKKIIKVRRDKDGPGREGGRRNLLVDAAEAGLLSRDKDPRGPSSGSCID
QLPIKMDYGEELRSPITSLTPGESKTTSPSSPEEDVMLGSLTFSVDYNFPKKALVVTIQE
AHGLPVMDDQTQGSDPYIKMTILPDKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQLQDL
VLHFLVLSFDRFSRDDVIGEVMVPLAGVDPSTGKVQLTRDIIKRNIQKCISRGELQVSLS
YQPVAQRMTVVVLKARHLPKMDITGLSGNPYVKVNVYYGRKRIAKKKTHVKKCTLNPIFN
ESFIYDIPTDLLPDISIEFLVIDFDRTTKNEVVGRLILGAHSVTASGAEHWREVCESPRK
PVAKWHSLSEY
GenBank ID Protein 14042290
UniProtKB/Swiss-Prot ID Q9BT88
UniProtKB/Swiss-Prot Entry Name SYT11_HUMAN
PDB IDs Not Available
GenBank Gene ID AK027540
GeneCard ID SYT11
GenAtlas ID SYT11
HGNC ID HGNC:19239
References
General References Not Available