Identification
HMDB Protein ID CDBP03226
Secondary Accession Numbers Not Available
Name Translocon-associated protein subunit gamma
Description Not Available
Synonyms
  1. SSR-gamma
  2. Signal sequence receptor subunit gamma
  3. TRAP-gamma
Gene Name SSR3
Protein Type Enzyme
Biological Properties
General Function Involved in cotranslational protein targeting to membrane
Specific Function TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins
GO Classification
Component
intrinsic to membrane
protein complex
intrinsic to organelle membrane
intrinsic to endoplasmic reticulum membrane
integral to endoplasmic reticulum membrane
cell part
membrane part
translocon complex
sec61 translocon complex
macromolecular complex
Process
protein targeting to membrane
cotranslational protein targeting to membrane
establishment of localization
transport
protein transport
intracellular protein transport
protein targeting
Cellular Location
  1. Endoplasmic reticulum membrane
  2. Multi-pass membrane protein
Pathways
Gene Properties
Chromosome Location Chromosome:3
Locus 3q25.31
SNPs SSR3
Gene Sequence
>558 bp
ATGGCTCCTAAAGGCAGCTCCAAACAGCAGTCTGAGGAGGACCTGCTCCTGCAGGATTTC
AGCCGCAATCTCTCGGCCAAGTCCTCCGCGCTCTTCTTCGGAAACGCGTTCATCGTGTCT
GCCATCCCCATCTGGTTATACTGGCGAATATGGCATATGGATCTTATTCAGTCTGCTGTT
TTGTATAGTGTGATGACCCTAGTAAGCACATATTTGGTAGCCTTTGCATACAAGAATGTG
AAATTTGTTCTCAAGCACAAAGTAGCACAGAAGAGGGAGGATGCTGTTTCCAAAGAAGTG
ACTCGAAAACTTTCTGAAGCTGATAATAGAAAGATGTCTCGGAAGGAGAAAGATGAAAGA
ATCTTGTGGAAGAAGAATGAAGTTGCTGATTATGAAGCTACAACATTTTCCATCTTCTAT
AACAACACTCTGTTCCTGGTCGTGGTCATTGTTGCTTCCTTCTTCATATTGAAGAACTTC
AACCCCACAGTGAACTACATATTGTCCATAAGTGCTTCATCAGGACTCATCGCCCTCCTG
TCTACTGGCTCCAAATAG
Protein Properties
Number of Residues 185
Molecular Weight 21080.3
Theoretical pI 10.17
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["28-48", "55-76", "136-157", "164-184"]
Protein Sequence
>Translocon-associated protein subunit gamma
MAPKGSSKQQSEEDLLLQDFSRNLSAKSSALFFGNAFIVSAIPIWLYWRIWHMDLIQSAV
LYSVMTLVSTYLVAFAYKNVKFVLKHKVAQKREDAVSKEVTRKLSEADNRKMSRKEKDER
ILWKKNEVADYEATTFSIFYNNTLFLVVVIVASFFILKNFNPTVNYILSISASSGLIALL
STGSK
GenBank ID Protein 33150654
UniProtKB/Swiss-Prot ID Q9UNL2
UniProtKB/Swiss-Prot Entry Name SSRG_HUMAN
PDB IDs Not Available
GenBank Gene ID AF087907
GeneCard ID SSR3
GenAtlas ID SSR3
HGNC ID HGNC:11325
References
General References Not Available