Identification |
HMDB Protein ID
| CDBP03226 |
Secondary Accession Numbers
| Not Available |
Name
| Translocon-associated protein subunit gamma |
Description
| Not Available |
Synonyms
|
- SSR-gamma
- Signal sequence receptor subunit gamma
- TRAP-gamma
|
Gene Name
| SSR3 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in cotranslational protein targeting to membrane |
Specific Function
| TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins |
GO Classification
|
Component |
intrinsic to membrane |
protein complex |
intrinsic to organelle membrane |
intrinsic to endoplasmic reticulum membrane |
integral to endoplasmic reticulum membrane |
cell part |
membrane part |
translocon complex |
sec61 translocon complex |
macromolecular complex |
Process |
protein targeting to membrane |
cotranslational protein targeting to membrane |
establishment of localization |
transport |
protein transport |
intracellular protein transport |
protein targeting |
|
Cellular Location
|
- Endoplasmic reticulum membrane
- Multi-pass membrane protein
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:3 |
Locus
| 3q25.31 |
SNPs
| SSR3 |
Gene Sequence
|
>558 bp
ATGGCTCCTAAAGGCAGCTCCAAACAGCAGTCTGAGGAGGACCTGCTCCTGCAGGATTTC
AGCCGCAATCTCTCGGCCAAGTCCTCCGCGCTCTTCTTCGGAAACGCGTTCATCGTGTCT
GCCATCCCCATCTGGTTATACTGGCGAATATGGCATATGGATCTTATTCAGTCTGCTGTT
TTGTATAGTGTGATGACCCTAGTAAGCACATATTTGGTAGCCTTTGCATACAAGAATGTG
AAATTTGTTCTCAAGCACAAAGTAGCACAGAAGAGGGAGGATGCTGTTTCCAAAGAAGTG
ACTCGAAAACTTTCTGAAGCTGATAATAGAAAGATGTCTCGGAAGGAGAAAGATGAAAGA
ATCTTGTGGAAGAAGAATGAAGTTGCTGATTATGAAGCTACAACATTTTCCATCTTCTAT
AACAACACTCTGTTCCTGGTCGTGGTCATTGTTGCTTCCTTCTTCATATTGAAGAACTTC
AACCCCACAGTGAACTACATATTGTCCATAAGTGCTTCATCAGGACTCATCGCCCTCCTG
TCTACTGGCTCCAAATAG
|
Protein Properties |
Number of Residues
| 185 |
Molecular Weight
| 21080.3 |
Theoretical pI
| 10.17 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
- ["28-48", "55-76", "136-157", "164-184"]
|
Protein Sequence
|
>Translocon-associated protein subunit gamma
MAPKGSSKQQSEEDLLLQDFSRNLSAKSSALFFGNAFIVSAIPIWLYWRIWHMDLIQSAV
LYSVMTLVSTYLVAFAYKNVKFVLKHKVAQKREDAVSKEVTRKLSEADNRKMSRKEKDER
ILWKKNEVADYEATTFSIFYNNTLFLVVVIVASFFILKNFNPTVNYILSISASSGLIALL
STGSK
|
External Links |
GenBank ID Protein
| 33150654 |
UniProtKB/Swiss-Prot ID
| Q9UNL2 |
UniProtKB/Swiss-Prot Entry Name
| SSRG_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| AF087907 |
GeneCard ID
| SSR3 |
GenAtlas ID
| SSR3 |
HGNC ID
| HGNC:11325 |
References |
General References
| Not Available |