Identification
HMDB Protein ID CDBP03224
Secondary Accession Numbers Not Available
Name Translocon-associated protein subunit beta
Description Not Available
Synonyms
  1. SSR-beta
  2. Signal sequence receptor subunit beta
  3. TRAP-beta
Gene Name SSR2
Protein Type Enzyme
Biological Properties
General Function Involved in signal sequence binding
Specific Function TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins
GO Classification
Component
organelle
membrane-bounded organelle
intracellular membrane-bounded organelle
integral to membrane
cell part
membrane part
endoplasmic reticulum
intrinsic to membrane
Cellular Location
  1. Endoplasmic reticulum membrane
  2. Single-pass type I membrane protein
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 1q21-q23
SNPs SSR2
Gene Sequence
>552 bp
ATGAGGCTGCTGTCATTTGTGGTGTTGGCTCTATTTGCTGTCACTCAAGCAGAGGAAGGA
GCCAGGCTTTTGGCTTCCAAATCACTGCTGAACAGATACGCCGTGGAGGGACGAGACCTG
ACCTTGCAGTACAACACCTACAATGTTGGCTCAAGTGCTGCATTAGACGTGGAACTATCT
GATGATTCCTTCCCTCCAGAAGACTTTGGCATTGTGTCTGGAATGCTCAATGTCAAATGG
GACCGGATTGCCCCTGCTAGCAATGTCTCCCACACTGTGGTCCTGCGCCCTCTCAAGGCT
GGTTATTTCAACTTCACCTCGGCAACAATTACTTACCTGGCCCAGGAGGATGGGCCCGTT
GTGATTGGCTCTACCAGTGCACCTGGACAGGGAGGAATCCTGGCTCAGCGGGAGTTTGAC
AGGCGATTCTCCCCTCATTTTCTGGACTGGGCAGCCTTTGGGGTCATGACCCTTCCCTCC
ATCGGCATCCCCCTGCTATTGTGGTACTCCAGCAAGAGGAAATATGACACTCCCAAAACG
AAGAAGAACTGA
Protein Properties
Number of Residues 183
Molecular Weight 20134.8
Theoretical pI 8.79
Pfam Domain Function
Signals
  • ["1-17"]
Transmembrane Regions
  • ["150-169"]
Protein Sequence
>Translocon-associated protein subunit beta
MRLLSFVVLALFAVTQAEEGARLLASKSLLNRYAVEGRDLTLQYNIYNVGSSAALDVELS
DDSFPPEDFGIVSGMLNVKWDRIAPASNVSHTVVLRPLKAGYFNFTSATITYLAQEDGPV
VIGSTSAPGQGGILAQREFDRRFSPHFLDWAAFGVMTLPSIGIPLLLWYSSKRKYDTPKT
KKN
GenBank ID Protein 62896759
UniProtKB/Swiss-Prot ID P43308
UniProtKB/Swiss-Prot Entry Name SSRB_HUMAN
PDB IDs Not Available
GenBank Gene ID AK222600
GeneCard ID SSR2
GenAtlas ID SSR2
HGNC ID HGNC:11324
References
General References Not Available