| Identification |
|---|
| HMDB Protein ID
| CDBP03223 |
| Secondary Accession Numbers
| Not Available |
| Name
| Translocon-associated protein subunit alpha |
| Description
| Not Available |
| Synonyms
|
- SSR-alpha
- Signal sequence receptor subunit alpha
- TRAP-alpha
|
| Gene Name
| SSR1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in signal sequence binding |
| Specific Function
| TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. May be involved in the recycling of the translocation apparatus after completion of the translocation process or may function as a membrane-bound chaperone facilitating folding of translocated proteins |
| GO Classification
|
| Component |
| endoplasmic reticulum |
| organelle |
| membrane-bounded organelle |
| intracellular membrane-bounded organelle |
|
| Cellular Location
|
- Endoplasmic reticulum membrane
- Single-pass type I membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:6 |
| Locus
| 6p24.3 |
| SNPs
| SSR1 |
| Gene Sequence
|
>861 bp
ATGAGACTCCTCCCCCGCTTGCTGCTGCTTCTCTTACTCGTGTTCCCTGCCACTGTCTTG
TTCCGAGGCGGCCCCAGAGGCTTGTTAGCAGTGGCACAAGATCTTACAGAGGATGAAGAA
ACAGTAGAAGATTCCATAATTGAGGATGAAGATGATGAAGCCGAGGTAGAAGAAGATGAA
CCCACAGATTTGGTAGAAGATAAAGAGGAAGAAGATGTGTCTGGTGAACCTGAAGCTTCA
CCGAGTGCAGATACAACTATACTGTTTGTAAAAGGAGAAGATTTTCCAGCAAATAACATT
GTGAAGTTCCTGGTAGGCTTTACCAACAAGGGTACAGAAGATTTTATTGTTGAATCCTTA
GATGCCTCATTCCGTTATCCTCAGGACTACCAGTTTTATATCCAGAATTTCACAGCTCTT
CCTCTGAACACTGTAGTGCCACCCCAGAGACAGGCAACTTTTGAGTACTCTTTCATTCCT
GCAGAGCCCATGGGCGGACGACCATTTGGTTTGGTCATCAATCTGAACTACAAAGATTTG
AACGGCAATGTATTCCAAGATGCAGTCTTCAATCAAACAGTTACAGTTATTGAAAGAGAG
GATGGGTTAGATGGAGAAACAATCTTTATGTATATGTTCCTTGCTGGTCTTGGGCTTCTG
GTTATTGTTGGCCTTCATCAACTCCTAGAATCTAGAAAGCGTAAGAGACCCATACAGAAA
GTAGAAATGGGTACATCAAGTCAGAATGATGTTGACATGAGTTGGATTCCTCAGGAAACA
TTGAATCAAATCAATAAAGCTTCACCAAGAAGGTTGCCCAGGAAACGGGCACAGAAGAGA
TCAGTGGGATCTGATGAGTAA
|
| Protein Properties |
|---|
| Number of Residues
| 286 |
| Molecular Weight
| 32235.1 |
| Theoretical pI
| 4.11 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Translocon-associated protein subunit alpha
MRLLPRLLLLLLLVFPATVLFRGGPRGLLAVAQDLTEDEETVEDSIIEDEDDEAEVEEDE
PTDLVEDKEEEDVSGEPEASPSADTTILFVKGEDFPANNIVKFLVGFTNKGTEDFIVESL
DASFRYPQDYQFYIQNFTALPLNTVVPPQRQATFEYSFIPAEPMGGRPFGLVINLNYKDL
NGNVFQDAVFNQTVTVIEREDGLDGETIFMYMFLAGLGLLVIVGLHQLLESRKRKRPIQK
VEMGTSSQNDVDMSWIPQETLNQINKASPRRLPRKRAQKRSVGSDE
|
| External Links |
|---|
| GenBank ID Protein
| 5731113 |
| UniProtKB/Swiss-Prot ID
| P43307 |
| UniProtKB/Swiss-Prot Entry Name
| SSRA_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF156965 |
| GeneCard ID
| SSR1 |
| GenAtlas ID
| SSR1 |
| HGNC ID
| HGNC:11323 |
| References |
|---|
| General References
| Not Available |