Identification |
HMDB Protein ID
| CDBP03206 |
Secondary Accession Numbers
| Not Available |
Name
| Calcium-binding mitochondrial carrier protein SCaMC-1 |
Description
| Not Available |
Synonyms
|
- Mitochondrial ATP-Mg/Pi carrier protein 1
- Mitochondrial Ca(2+)-dependent solute carrier protein 1
- Small calcium-binding mitochondrial carrier protein 1
- Solute carrier family 25 member 24
|
Gene Name
| SLC25A24 |
Protein Type
| Metal Binding |
Biological Properties |
General Function
| Involved in calcium ion binding |
Specific Function
| Calcium-dependent mitochondrial solute carrier. Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. May act as a ATP-Mg/Pi exchanger that mediates the transport of Mg-ATP in exchange for phosphate, catalyzing the net uptake or efflux of adenine nucleotides into or from the mitochondria.
|
GO Classification
|
Biological Process |
transmembrane transport |
Cellular Component |
integral to membrane |
mitochondrial inner membrane |
Component |
membrane |
cell part |
organelle membrane |
organelle inner membrane |
mitochondrial inner membrane |
Function |
ion binding |
cation binding |
metal ion binding |
binding |
calcium ion binding |
Molecular Function |
calcium ion binding |
Process |
establishment of localization |
transport |
transmembrane transport |
|
Cellular Location
|
- Mitochondrion inner membrane
- Multi-pass membrane protein
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| 1 |
Locus
| 1p13.3 |
SNPs
| SLC25A24 |
Gene Sequence
|
>1434 bp
ATGTTGCGCTGGCTGCGGGACTTCGTGCTGCCCACCGCGGCCTGCCAGGACGCGGAGCAG
CCGACGCGCTACGAGACCCTCTTCCAGGCACTGGACCGCAATGGGGACGGAGTGGTGGAC
ATCGGCGAGCTGCAGGAGGGGCTCAGGAACCTGGGCATCCCTCTGGGCCAGGACGCCGAG
GAGAAAATTTTTACTACTGGAGATGTCAACAAAGATGGGAAGCTGGATTTTGAAGAATTT
ATGAAGTACCTTAAAGACCATGAGAAGAAAATGAAATTGGCATTTAAGAGTTTAGACAAA
AATAATGATGGAAAAATTGAGGCTTCAGAAATTGTCCAGTCTCTCCAGACACTGGGTCTG
ACTATTTCTGAACAACAAGCAGAGTTGATTCTTCAAAGCATTGATGTTGATGGGACAATG
ACAGTGGACTGGAATGAATGGAGAGACTACTTCTTATTTAATCCTGTTACAGACATTGAG
GAAATTATCCGTTTCTGGAAACATTCTACAGGAATTGACATAGGGGATAGCTTAACTATT
CCAGATGAATTCACGGAAGACGAAAAAAAATCCGGACAATGGTGGAGGCAGCTTTTGGCA
GGAGGCATTGCTGGTGCTGTCTCTCGAACAAGCACTGCCCCTTTGGACCGTCTGAAAATC
ATGATGCAGGTTCACGGTTCAAAATCAGACAAAATGAACATATTTGGTGGCTTTCGACAG
ATGGTAAAAGAAGGAGGTATCCGCTCGCTTTGGAGGGGAAATGGTACAAACGTCATCAAA
ATTGCTCCTGAGACAGCTGTTAAATTCTGGGCATATGAACAGTACAAGAAGTTACTTACT
GAAGAAGGACAAAAAATAGGAACATTTGAGAGATTTATTTCTGGTTCCATGGCTGGAGCA
ACTGCACAGACTTTTATATATCCAATGGAGGTTATGAAAACCAGGCTGGCTGTAGGCAAA
ACTGGGCAGTACTCTGGAATATATGATTGTGCCAAGAAGATTTTGAAACATGAAGGCTTG
GGAGCTTTTTACAAAGGCTATGTTCCCAATTTATTAGGTATCATACCTTATGCAGGCATA
GATCTTGCTGTGTATGAGCTCTTGAAGTCCTATTGGCTGGATAATTTTGCAAAAGATTCT
GTAAACCCTGGAGTCATGGTGTTGCTGGGATGCGGTGCCTTATCCAGCACCTGTGGTCAG
CTGGCCAGCTACCCATTGGCTTTGGTGAGAACTCGCATGCAGGCTCAAGCCATGTTAGAA
GGTTCCCCACAGCTGAATATGGTTGGCCTCTTTCGACGAATTATTTCCAAAGAAGGAATA
CCAGGACTTTACAGAGGCATCACCCCAAACTTCATGAAGGTGCTCCCTGCTGTAGGCATC
AGTTATGTGGTTTATGAAAATATGAAGCAAACTTTAGGAGTAACCCAGAAATGA
|
Protein Properties |
Number of Residues
| 477 |
Molecular Weight
| 53354.08 |
Theoretical pI
| 6.33 |
Pfam Domain Function
|
|
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
>Calcium-binding mitochondrial carrier protein SCaMC-1
MLRWLRDFVLPTAACQDAEQPTRYETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAE
EKIFTTGDVNKDGKLDFEEFMKYLKDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGL
TISEQQAELILQSIDVDGTMTVDWNEWRDYFLFNPVTDIEEIIRFWKHSTGIDIGDSLTI
PDEFTEDEKKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQ
MVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGA
TAQTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGI
DLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLE
GSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQTLGVTQK
|
External Links |
GenBank ID Protein
| 148491091 |
UniProtKB/Swiss-Prot ID
| Q6NUK1 |
UniProtKB/Swiss-Prot Entry Name
| SCMC1_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| NM_013386.3 |
GeneCard ID
| SLC25A24 |
GenAtlas ID
| SLC25A24 |
HGNC ID
| HGNC:20662 |
References |
General References
| Not Available |