Identification
HMDB Protein ID CDBP03206
Secondary Accession Numbers Not Available
Name Calcium-binding mitochondrial carrier protein SCaMC-1
Description Not Available
Synonyms
  1. Mitochondrial ATP-Mg/Pi carrier protein 1
  2. Mitochondrial Ca(2+)-dependent solute carrier protein 1
  3. Small calcium-binding mitochondrial carrier protein 1
  4. Solute carrier family 25 member 24
Gene Name SLC25A24
Protein Type Metal Binding
Biological Properties
General Function Involved in calcium ion binding
Specific Function Calcium-dependent mitochondrial solute carrier. Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. May act as a ATP-Mg/Pi exchanger that mediates the transport of Mg-ATP in exchange for phosphate, catalyzing the net uptake or efflux of adenine nucleotides into or from the mitochondria.
GO Classification
Biological Process
transmembrane transport
Cellular Component
integral to membrane
mitochondrial inner membrane
Component
membrane
cell part
organelle membrane
organelle inner membrane
mitochondrial inner membrane
Function
ion binding
cation binding
metal ion binding
binding
calcium ion binding
Molecular Function
calcium ion binding
Process
establishment of localization
transport
transmembrane transport
Cellular Location
  1. Mitochondrion inner membrane
  2. Multi-pass membrane protein
Pathways
Gene Properties
Chromosome Location 1
Locus 1p13.3
SNPs SLC25A24
Gene Sequence
>1434 bp
ATGTTGCGCTGGCTGCGGGACTTCGTGCTGCCCACCGCGGCCTGCCAGGACGCGGAGCAG
CCGACGCGCTACGAGACCCTCTTCCAGGCACTGGACCGCAATGGGGACGGAGTGGTGGAC
ATCGGCGAGCTGCAGGAGGGGCTCAGGAACCTGGGCATCCCTCTGGGCCAGGACGCCGAG
GAGAAAATTTTTACTACTGGAGATGTCAACAAAGATGGGAAGCTGGATTTTGAAGAATTT
ATGAAGTACCTTAAAGACCATGAGAAGAAAATGAAATTGGCATTTAAGAGTTTAGACAAA
AATAATGATGGAAAAATTGAGGCTTCAGAAATTGTCCAGTCTCTCCAGACACTGGGTCTG
ACTATTTCTGAACAACAAGCAGAGTTGATTCTTCAAAGCATTGATGTTGATGGGACAATG
ACAGTGGACTGGAATGAATGGAGAGACTACTTCTTATTTAATCCTGTTACAGACATTGAG
GAAATTATCCGTTTCTGGAAACATTCTACAGGAATTGACATAGGGGATAGCTTAACTATT
CCAGATGAATTCACGGAAGACGAAAAAAAATCCGGACAATGGTGGAGGCAGCTTTTGGCA
GGAGGCATTGCTGGTGCTGTCTCTCGAACAAGCACTGCCCCTTTGGACCGTCTGAAAATC
ATGATGCAGGTTCACGGTTCAAAATCAGACAAAATGAACATATTTGGTGGCTTTCGACAG
ATGGTAAAAGAAGGAGGTATCCGCTCGCTTTGGAGGGGAAATGGTACAAACGTCATCAAA
ATTGCTCCTGAGACAGCTGTTAAATTCTGGGCATATGAACAGTACAAGAAGTTACTTACT
GAAGAAGGACAAAAAATAGGAACATTTGAGAGATTTATTTCTGGTTCCATGGCTGGAGCA
ACTGCACAGACTTTTATATATCCAATGGAGGTTATGAAAACCAGGCTGGCTGTAGGCAAA
ACTGGGCAGTACTCTGGAATATATGATTGTGCCAAGAAGATTTTGAAACATGAAGGCTTG
GGAGCTTTTTACAAAGGCTATGTTCCCAATTTATTAGGTATCATACCTTATGCAGGCATA
GATCTTGCTGTGTATGAGCTCTTGAAGTCCTATTGGCTGGATAATTTTGCAAAAGATTCT
GTAAACCCTGGAGTCATGGTGTTGCTGGGATGCGGTGCCTTATCCAGCACCTGTGGTCAG
CTGGCCAGCTACCCATTGGCTTTGGTGAGAACTCGCATGCAGGCTCAAGCCATGTTAGAA
GGTTCCCCACAGCTGAATATGGTTGGCCTCTTTCGACGAATTATTTCCAAAGAAGGAATA
CCAGGACTTTACAGAGGCATCACCCCAAACTTCATGAAGGTGCTCCCTGCTGTAGGCATC
AGTTATGTGGTTTATGAAAATATGAAGCAAACTTTAGGAGTAACCCAGAAATGA
Protein Properties
Number of Residues 477
Molecular Weight 53354.08
Theoretical pI 6.33
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence
>Calcium-binding mitochondrial carrier protein SCaMC-1
MLRWLRDFVLPTAACQDAEQPTRYETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAE
EKIFTTGDVNKDGKLDFEEFMKYLKDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGL
TISEQQAELILQSIDVDGTMTVDWNEWRDYFLFNPVTDIEEIIRFWKHSTGIDIGDSLTI
PDEFTEDEKKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQ
MVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGA
TAQTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGI
DLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLE
GSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQTLGVTQK
GenBank ID Protein 148491091
UniProtKB/Swiss-Prot ID Q6NUK1
UniProtKB/Swiss-Prot Entry Name SCMC1_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_013386.3
GeneCard ID SLC25A24
GenAtlas ID SLC25A24
HGNC ID HGNC:20662
References
General References Not Available