| Identification |
|---|
| HMDB Protein ID
| CDBP03204 |
| Secondary Accession Numbers
| Not Available |
| Name
| Protein transport protein Sec31A |
| Description
| Not Available |
| Synonyms
|
- ABP125
- ABP130
- SEC31-like protein 1
- SEC31-related protein A
- Web1-like protein
|
| Gene Name
| SEC31A |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Transcription |
| Specific Function
| Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Cytoplasm
- Peripheral membrane protein
- Peripheral membrane protein
- Cytoplasmic vesicle
- Endoplasmic reticulum membrane
- Cytoplasmic side
- COPII-coated vesicle membrane
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:4 |
| Locus
| 4q21.22 |
| SNPs
| SEC31A |
| Gene Sequence
|
>3663 bp
ATGAAGTTAAAGGAAGTAGATCGTACAGCCATGCAGGCATGGAGCCCTGCCCAGAATCAC
CCCATTTACCTAGCAACAGGAACATCTGCTCAGCAATTGGATGCAACATTTAGTACGAAT
GCTTCCCTTGAGATATTTGAATTAGACCTCTCTGATCCATCCTTGGATATGAAATCTTGT
GCCACATTCTCCTCTTCTCACAGGTACCACAAGTTGATTTGGGGGCCTTATAAAATGGAT
TCCAAAGGAGATGTCTCTGGAGTTCTGATTGCAGGTGGTGAAAATGGAAATATTATTCTC
TATGATCCTTCTAAAATTATAGCTGGAGACAAGGAAGTTGTGATTGCCCAGAATGACAAG
CATACTGGCCCAGTGAGAGCCTTGGATGTGAACATTTTCCAGACTAATCTGGTAGCTTCT
GGTGCTAATGAATCTGAAATCTACATATGGGATCTAAATAATTTTGCAACCCCAATGACA
CCAGGAGCCAAAACACAGCCGCCAGAAGATATCAGCTGCATTGCATGGAACAGACAAGTT
CAGCATATTTTAGCATCAGCCAGTCCCAGTGGCCGGGCCACTGTATGGGATCTTAGAAAA
AATGAGCCAATCATCAAAGTCAGTGACCATAGTAACAGAATGCATTGTTCTGGGTTGGCA
TGGCATCCTGATGTTGCTACTCAGATGGTCCTTGCCTCCGAGGATGACCGGTTACCAGTG
ATCCAGATGTGGGATCTTCGATTTGCTTCCTCTCCACTTCGTGTCCTGGAAAACCATGCC
AGGGGGATTTTGGCAATTGCTTGGAGCATGGCAGATCCTGAATTGTTACTGAGCTGTGGA
AAAGATGCTAAGATTCTCTGCTCCAATCCAAACACAGGAGAGGTGTTATATGAACTTCCC
ACCAACACACAGTGGTGCTTCGATATTCAGTGGTGTCCCCGAAATCCTGCTGTCTTATCA
GCTGCTTCGTTTGATGGGCGTATCAGTGTTTATTCTATCATGGGAGGAAGCACAGATGGT
TTAAGACAGAAACAAGTTGACAAGCTTTCATCATCTTTTGGGAATCTTGATCCCTTTGGC
ACAGGACAGCCCCTTCCTCCGTTACAAATTCCACAGCAGACTGCTCAGCATAGTATAGTG
CTGCCTCTGAAGAAGCCGCCCAAGTGGATTCGAAGGCCTGTTGGTGCTTCTTTTTCATTT
GGAGGCAAACTGGTTACGTTTGAGAATGTCAGAATGCCTTCTCATCAGGGAGCTGAGCAG
CAGCAGCAGCAGCACCATGTGTTCATTAGTCAGGTTGTAACAGAAAAGGAGTTCCTCAGC
CGATCAGACCAACTTCAGCAGGCTGTGCAGTCACAAGGATTTATCAATTATTGCCAAAAA
AAAATTGATGCTTCTCAGACTGAATTTGAGAAAAATGTGTGGTCCTTTTTGAAGGTAAAC
TTTGAGGATGATTCTCGTGGAAAATACCTTGAACTTCTAGGATACAGAAAAGAAGATCTA
GGAAAGAAGATTGCTTTGGCCTTGAACAAAGTGGATGGAGCCAATGTGGCTCTTAAAGAC
TCTGACCAAGTAGCACAGAGTGATGGGGAGGAGAGCCCTGCTGCTGAAGAGCAGCTCTTG
GGAGAGCACATTAAAGAGGAAAAAGAAGAATCTGAATTTCTACCCTCATCTGGAGGAACA
TTTAATATCTCTGTCAGTGGGGACATTGATGGTTTAATTACTCAGGCTTTGCTGACGGGC
AATTTTGAGAGTGCTGTTGACCTTTGTTTACATGATAACCGCATGGCCGATGCCATTATA
TTGGCCATAGCAGGTGGACAAGAACTCTTGGCTCGAACCCAGAAAAAATACTTCGCAAAA
TCCCAAAGCAAAATTACCAGGCTCATCACTGCAGTGGTGATGAAGAACTGGAAAGAGATT
GTTGAGTCTTGTGATCTTAAAAATTGGAGAGAGGCTTTAGCTGCAGTATTGACTTATGCA
AAGCCGGATGAATTTTCAGCCCTTTGTGATCTTTTGGGAACCAGGCTTGAAAATGAAGGA
GATAGCCTCCTGCAGACTCAAGCATGTCTCTGCTATATTTGTGCAGGGAATGTAGAGAAA
TTAGTTGCATGTTGGACTAAAGCTCAAGATGGAAGCCACCCTTTGTCACTTCAGGATCTG
ATTGAGAAAGTTGTCATCCTGCGAAAAGCTGTGCAACTCACTCAAGCCATGGACACTAGT
ACTGTAGGAGTTCTCTTGGCTGCGAAGATGAGTCAGTATGCCAATTTGTTGGCAGCTCAG
GGCAGTATTGCTGCAGCCTTGGCTTTTCTTCCTGACAACACCAACCAGCCAAATATCATG
CAGCTTCGTGACAGACTTTGTAGAGCACAAGGAGAGCCTGTAGCAGGACATGAATCACCT
AAAATTCCGTACGAGAAACAGCAGCTCCCCAAGGGCAGGCCTGGACCAGTTGCTGGCCAC
CACCAGATGCCAAGAGTTCAAACTCAACAATATTATCCCCATGGAGAAAATCCTCCACCT
CCGGGTTTCATAATGCATGGAAATGTTAATCCAAATGCTGCTGGTCAGCTTCCCACATCT
CCAGGTCATATGCACACCCAGGTACCACCTTATCCACAGCCACAGCCTTATCAACCAGCC
CAGCCGTATCCCTTCGGAACAGGGGGGTCAGCAATGTATCGACCTCAGCAGCCTGTTGCT
CCTCCTACTTCAAACGCTTACCCTAACACCCCTTACATATCTTCTGCTTCTTCCTATACT
GGGCAGTCTCAGCTGTACGCAGCACAGCACCAGGCCTCTTCACCTACCTCCAGCCCTGCT
ACTTCTTTCCCTCCTCCCCCTTCCTCTGGAGCATCCTTCCAGCATGGCGGACCAGGAGCT
CCACCATCATCTTCAGCTTATGCACTGCCTCCTGGAACAACAGGTACACTGCCTGCTGCC
AGTGAGCTGCCTGCGTCCCAAAGAACAGGTCCTCAGAATGGTTGGAATGACCCTCCAGCT
TTGAACAGAGTACCCAAAAAGAAGAAGATGCCTGAAAACTTCATGCCTCCTGTTCCCATC
ACATCACCAATCATGAACCCGTTGGGTGACCCCCAGTCACAAATGCTGCAGCAACAGCCT
TCAGCTCCAGTACCACTGTCAAGCCAGTCTTCATTCCCACAGCCACATCTTCCAGGTGGC
CAGCCCTTCCATGGCGTACAGCAACCTCTTGGTCAAACAGGCATGCCACCATCTTTTTCA
AAGCCCAATATTGAAGGTGCCCCAGGGGCTCCTATTGGAAATACCTTCCAGCATGTGCAG
TCTTTGCCAACAAAAAAAATTACCAAGAAACCTATTCCAGATGAGCACCTCATTCTAAAG
ACCACATTTGAGGATCTTATTCAGCGCTGCCTTTCTTCAGCAACAGACCCTCAAACCAAG
AGGAAGCTAGATGATGCCAGCAAACGTTTGGAGTTTCTGTATGATAAACTTAGGGAACAG
ACACTTTCACCAACAATCACCAGTGGTTTACACAACATTGCAAGGAGCATTGAAACTCGA
AACTACTCAGAAGGATTGACCATGCATACCCACATAGTTAGCACCAGCAACTTCAGTGAG
ACCTCTGCTTTCATGCCAGTTCTCAAAGTTGTTCTCACCCAGGCCAATAAGCTGGGTGTC
TAA
|
| Protein Properties |
|---|
| Number of Residues
| 1220 |
| Molecular Weight
| 133013.6 |
| Theoretical pI
| 6.89 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Protein transport protein Sec31A
MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC
ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK
HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV
QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPV
IQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELP
TNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG
TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQ
QQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVN
FEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQLL
GEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAII
LAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYA
KPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL
IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIM
QLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPP
PGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQPVA
PPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGA
PPSSSAYALPPGTTGTLPAASELPASQRTGPQNGWNDPPALNRVPKKKKMPENFMPPVPI
TSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFS
KPNIEGAPGAPIGNTFQHVQSLPTKKITKKPIPDEHLILKTTFEDLIQRCLSSATDPQTK
RKLDDASKRLEFLYDKLREQTLSPTITSGLHNIARSIETRNYSEGLTMHTHIVSTSNFSE
TSAFMPVLKVVLTQANKLGV
|
| External Links |
|---|
| GenBank ID Protein
| 116256338 |
| UniProtKB/Swiss-Prot ID
| O94979 |
| UniProtKB/Swiss-Prot Entry Name
| SC31A_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_001077207.2 |
| GeneCard ID
| SEC31A |
| GenAtlas ID
| SEC31A |
| HGNC ID
| HGNC:17052 |
| References |
|---|
| General References
| Not Available |