Identification
HMDB Protein ID CDBP03204
Secondary Accession Numbers Not Available
Name Protein transport protein Sec31A
Description Not Available
Synonyms
  1. ABP125
  2. ABP130
  3. SEC31-like protein 1
  4. SEC31-related protein A
  5. Web1-like protein
Gene Name SEC31A
Protein Type Enzyme
Biological Properties
General Function Transcription
Specific Function Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules
GO Classification Not Available
Cellular Location
  1. Cytoplasm
  2. Peripheral membrane protein
  3. Peripheral membrane protein
  4. Cytoplasmic vesicle
  5. Endoplasmic reticulum membrane
  6. Cytoplasmic side
  7. COPII-coated vesicle membrane
Pathways
Gene Properties
Chromosome Location Chromosome:4
Locus 4q21.22
SNPs SEC31A
Gene Sequence
>3663 bp
ATGAAGTTAAAGGAAGTAGATCGTACAGCCATGCAGGCATGGAGCCCTGCCCAGAATCAC
CCCATTTACCTAGCAACAGGAACATCTGCTCAGCAATTGGATGCAACATTTAGTACGAAT
GCTTCCCTTGAGATATTTGAATTAGACCTCTCTGATCCATCCTTGGATATGAAATCTTGT
GCCACATTCTCCTCTTCTCACAGGTACCACAAGTTGATTTGGGGGCCTTATAAAATGGAT
TCCAAAGGAGATGTCTCTGGAGTTCTGATTGCAGGTGGTGAAAATGGAAATATTATTCTC
TATGATCCTTCTAAAATTATAGCTGGAGACAAGGAAGTTGTGATTGCCCAGAATGACAAG
CATACTGGCCCAGTGAGAGCCTTGGATGTGAACATTTTCCAGACTAATCTGGTAGCTTCT
GGTGCTAATGAATCTGAAATCTACATATGGGATCTAAATAATTTTGCAACCCCAATGACA
CCAGGAGCCAAAACACAGCCGCCAGAAGATATCAGCTGCATTGCATGGAACAGACAAGTT
CAGCATATTTTAGCATCAGCCAGTCCCAGTGGCCGGGCCACTGTATGGGATCTTAGAAAA
AATGAGCCAATCATCAAAGTCAGTGACCATAGTAACAGAATGCATTGTTCTGGGTTGGCA
TGGCATCCTGATGTTGCTACTCAGATGGTCCTTGCCTCCGAGGATGACCGGTTACCAGTG
ATCCAGATGTGGGATCTTCGATTTGCTTCCTCTCCACTTCGTGTCCTGGAAAACCATGCC
AGGGGGATTTTGGCAATTGCTTGGAGCATGGCAGATCCTGAATTGTTACTGAGCTGTGGA
AAAGATGCTAAGATTCTCTGCTCCAATCCAAACACAGGAGAGGTGTTATATGAACTTCCC
ACCAACACACAGTGGTGCTTCGATATTCAGTGGTGTCCCCGAAATCCTGCTGTCTTATCA
GCTGCTTCGTTTGATGGGCGTATCAGTGTTTATTCTATCATGGGAGGAAGCACAGATGGT
TTAAGACAGAAACAAGTTGACAAGCTTTCATCATCTTTTGGGAATCTTGATCCCTTTGGC
ACAGGACAGCCCCTTCCTCCGTTACAAATTCCACAGCAGACTGCTCAGCATAGTATAGTG
CTGCCTCTGAAGAAGCCGCCCAAGTGGATTCGAAGGCCTGTTGGTGCTTCTTTTTCATTT
GGAGGCAAACTGGTTACGTTTGAGAATGTCAGAATGCCTTCTCATCAGGGAGCTGAGCAG
CAGCAGCAGCAGCACCATGTGTTCATTAGTCAGGTTGTAACAGAAAAGGAGTTCCTCAGC
CGATCAGACCAACTTCAGCAGGCTGTGCAGTCACAAGGATTTATCAATTATTGCCAAAAA
AAAATTGATGCTTCTCAGACTGAATTTGAGAAAAATGTGTGGTCCTTTTTGAAGGTAAAC
TTTGAGGATGATTCTCGTGGAAAATACCTTGAACTTCTAGGATACAGAAAAGAAGATCTA
GGAAAGAAGATTGCTTTGGCCTTGAACAAAGTGGATGGAGCCAATGTGGCTCTTAAAGAC
TCTGACCAAGTAGCACAGAGTGATGGGGAGGAGAGCCCTGCTGCTGAAGAGCAGCTCTTG
GGAGAGCACATTAAAGAGGAAAAAGAAGAATCTGAATTTCTACCCTCATCTGGAGGAACA
TTTAATATCTCTGTCAGTGGGGACATTGATGGTTTAATTACTCAGGCTTTGCTGACGGGC
AATTTTGAGAGTGCTGTTGACCTTTGTTTACATGATAACCGCATGGCCGATGCCATTATA
TTGGCCATAGCAGGTGGACAAGAACTCTTGGCTCGAACCCAGAAAAAATACTTCGCAAAA
TCCCAAAGCAAAATTACCAGGCTCATCACTGCAGTGGTGATGAAGAACTGGAAAGAGATT
GTTGAGTCTTGTGATCTTAAAAATTGGAGAGAGGCTTTAGCTGCAGTATTGACTTATGCA
AAGCCGGATGAATTTTCAGCCCTTTGTGATCTTTTGGGAACCAGGCTTGAAAATGAAGGA
GATAGCCTCCTGCAGACTCAAGCATGTCTCTGCTATATTTGTGCAGGGAATGTAGAGAAA
TTAGTTGCATGTTGGACTAAAGCTCAAGATGGAAGCCACCCTTTGTCACTTCAGGATCTG
ATTGAGAAAGTTGTCATCCTGCGAAAAGCTGTGCAACTCACTCAAGCCATGGACACTAGT
ACTGTAGGAGTTCTCTTGGCTGCGAAGATGAGTCAGTATGCCAATTTGTTGGCAGCTCAG
GGCAGTATTGCTGCAGCCTTGGCTTTTCTTCCTGACAACACCAACCAGCCAAATATCATG
CAGCTTCGTGACAGACTTTGTAGAGCACAAGGAGAGCCTGTAGCAGGACATGAATCACCT
AAAATTCCGTACGAGAAACAGCAGCTCCCCAAGGGCAGGCCTGGACCAGTTGCTGGCCAC
CACCAGATGCCAAGAGTTCAAACTCAACAATATTATCCCCATGGAGAAAATCCTCCACCT
CCGGGTTTCATAATGCATGGAAATGTTAATCCAAATGCTGCTGGTCAGCTTCCCACATCT
CCAGGTCATATGCACACCCAGGTACCACCTTATCCACAGCCACAGCCTTATCAACCAGCC
CAGCCGTATCCCTTCGGAACAGGGGGGTCAGCAATGTATCGACCTCAGCAGCCTGTTGCT
CCTCCTACTTCAAACGCTTACCCTAACACCCCTTACATATCTTCTGCTTCTTCCTATACT
GGGCAGTCTCAGCTGTACGCAGCACAGCACCAGGCCTCTTCACCTACCTCCAGCCCTGCT
ACTTCTTTCCCTCCTCCCCCTTCCTCTGGAGCATCCTTCCAGCATGGCGGACCAGGAGCT
CCACCATCATCTTCAGCTTATGCACTGCCTCCTGGAACAACAGGTACACTGCCTGCTGCC
AGTGAGCTGCCTGCGTCCCAAAGAACAGGTCCTCAGAATGGTTGGAATGACCCTCCAGCT
TTGAACAGAGTACCCAAAAAGAAGAAGATGCCTGAAAACTTCATGCCTCCTGTTCCCATC
ACATCACCAATCATGAACCCGTTGGGTGACCCCCAGTCACAAATGCTGCAGCAACAGCCT
TCAGCTCCAGTACCACTGTCAAGCCAGTCTTCATTCCCACAGCCACATCTTCCAGGTGGC
CAGCCCTTCCATGGCGTACAGCAACCTCTTGGTCAAACAGGCATGCCACCATCTTTTTCA
AAGCCCAATATTGAAGGTGCCCCAGGGGCTCCTATTGGAAATACCTTCCAGCATGTGCAG
TCTTTGCCAACAAAAAAAATTACCAAGAAACCTATTCCAGATGAGCACCTCATTCTAAAG
ACCACATTTGAGGATCTTATTCAGCGCTGCCTTTCTTCAGCAACAGACCCTCAAACCAAG
AGGAAGCTAGATGATGCCAGCAAACGTTTGGAGTTTCTGTATGATAAACTTAGGGAACAG
ACACTTTCACCAACAATCACCAGTGGTTTACACAACATTGCAAGGAGCATTGAAACTCGA
AACTACTCAGAAGGATTGACCATGCATACCCACATAGTTAGCACCAGCAACTTCAGTGAG
ACCTCTGCTTTCATGCCAGTTCTCAAAGTTGTTCTCACCCAGGCCAATAAGCTGGGTGTC
TAA
Protein Properties
Number of Residues 1220
Molecular Weight 133013.6
Theoretical pI 6.89
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>Protein transport protein Sec31A
MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC
ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK
HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV
QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPV
IQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELP
TNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG
TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQ
QQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVN
FEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQLL
GEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAII
LAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYA
KPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL
IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIM
QLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPP
PGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQPVA
PPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGA
PPSSSAYALPPGTTGTLPAASELPASQRTGPQNGWNDPPALNRVPKKKKMPENFMPPVPI
TSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFS
KPNIEGAPGAPIGNTFQHVQSLPTKKITKKPIPDEHLILKTTFEDLIQRCLSSATDPQTK
RKLDDASKRLEFLYDKLREQTLSPTITSGLHNIARSIETRNYSEGLTMHTHIVSTSNFSE
TSAFMPVLKVVLTQANKLGV
GenBank ID Protein 116256338
UniProtKB/Swiss-Prot ID O94979
UniProtKB/Swiss-Prot Entry Name SC31A_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_001077207.2
GeneCard ID SEC31A
GenAtlas ID SEC31A
HGNC ID HGNC:17052
References
General References Not Available