Cannabis Compound Database: Showing Protein GTP-binding protein REM 1 (CDBP03182)

Identification Biological properties Gene properties Protein properties External links References XML Show 1 compounds

Identification

HMDB Protein ID

CDBP03182

Secondary Accession Numbers

Not Available

Name

GTP-binding protein REM 1

Description

Not Available

Synonyms

GTPase-regulating endothelial cell sprouting
Rad and Gem-like GTP-binding protein 1

Gene Name

REM1

Protein Type

Enzyme

Biological Properties

General Function

Involved in GTP binding

Specific Function

Promotes endothelial cell sprouting and actin cytoskeletal reorganization. May be involved in angiogenesis. May function in Ca(2+) signaling

GO Classification

Component
membrane
cell part
Function
purine nucleotide binding
binding
nucleotide binding
catalytic activity
hydrolase activity
guanyl nucleotide binding
guanyl ribonucleotide binding
gtp binding
gtpase activity
nucleoside-triphosphatase activity
hydrolase activity, acting on acid anhydrides
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
pyrophosphatase activity
Process
signal transduction
intracellular signal transduction
small gtpase mediated signal transduction
biological regulation
regulation of biological process
regulation of cellular process

Cellular Location

Cytoplasmic

Pathways

Not Available

Gene Properties

Chromosome Location

Chromosome:2

Locus

20q11.21

SNPs

REM1

Gene Sequence

>897 bp
ATGACACTCAACACCGAGCAGGAAGCAAAGACCCCTCTGCACCGGCGAGCCAGCACCCCA
CTGCCCCTGTCCCCACGGGGCCACCAGCCTGGCCGCCTGAGCACAGTGCCTTCCACTCAA
TCCCAGCATCCCCGGCTGGGCCAATCAGCCTCCCTCAACCCTCCCACCCAGAAACCTTCA
CCTGCCCCAGATGATTGGTCTTCTGAATCCAGCGACTCTGAAGGCTCCTGGGAGGCTCTC
TACCGTGTGGTGCTACTTGGAGATCCTGGAGTGGGGAAGACCAGCTTGGCCAGCCTCTTT
GCAGGGAAGCAAGAGAGGGACCTCCATGAACAGCTGGGAGAAGATGTATATGAGAGGACC
CTCACGGTGGATGGAGAAGACACCACACTGGTGGTCGTGGACACCTGGGAGGCCGAGAAA
CTGGATAAAAGCTGGAGCCAGGAGTCATGCCTGCAGGGGGGCAGTGCCTATGTCATCGTA
TACTCCATCGCAGACCGAGGCAGCTTTGAGAGTGCCTCTGAGCTCCGCATCCAGCTGCGG
CGCACACATCAGGCAGACCATGTGCCCATCATCCTCGTGGGCAACAAGGCAGACTTGGCC
CGCTGCCGAGAAGTCTCTGTGGAAGTGGGCCGCGCCTGCGCTGTGGTGTTCGACTGTAAA
TTCATCGAGACATCCGCCACGCTGCAGCACAATGTGGCCGAGCTCTTCGAGGGCGTGGTG
CGCCAACTGCGCTTGCGCCGCCGGGACAGTGCGGCCAAGGAACCCCCAGCACCCCGACGG
CCGGCCAGCCTAGCCCAGCGCGCTCGTCGCTTCCTGGCACGCCTGACAGCCCGCAGCGCA
CGCCGCCGGGCACTCAAGGCCCGCTCCAAGTCCTGCCACAATCTGGCCGTGCTCTGA

Protein Properties

Number of Residues

298

Molecular Weight

32946.7

Theoretical pI

9.01

Pfam Domain Function

Ras (PF00071 )

Signals

["None"]

Transmembrane Regions

["None"]

Protein Sequence

>GTP-binding protein REM 1
MTLNTEQEAKTPLHRRASTPLPLSPRGHQPGRLSTVPSTQSQHPRLGQSASLNPPTQKPS
PAPDDWSSESSDSEGSWEALYRVVLLGDPGVGKTSLASLFAGKQERDLHEQLGEDVYERT
LTVDGEDTTLVVVDTWEAEKLDKSWSQESCLQGGSAYVIVYSIADRGSFESASELRIQLR
RTHQADHVPIILVGNKADLARCREVSVEEGRACAVVFDCKFIETSATLQHNVAELFEGVV
RQLRLRRRDSAAKEPPAPRRPASLAQRARRFLARLTARSARRRALKARSKSCHNLAVL

External Links

GenBank ID Protein

3462896

UniProtKB/Swiss-Prot ID

O75628

UniProtKB/Swiss-Prot Entry Name

REM1_HUMAN

PDB IDs

Not Available

GenBank Gene ID

AF084465

GeneCard ID