Identification
HMDB Protein ID CDBP03180
Secondary Accession Numbers Not Available
Name Lithostathine-1-alpha
Description Not Available
Synonyms
  1. ICRF
  2. Islet cells regeneration factor
  3. Islet of Langerhans regenerating protein
  4. PSP
  5. PTP
  6. Pancreatic stone protein
  7. Pancreatic thread protein
  8. REG
  9. REG-1-alpha
  10. Regenerating islet-derived protein 1-alpha
  11. Regenerating protein I alpha
Gene Name REG1A
Protein Type Enzyme
Biological Properties
General Function Involved in binding
Specific Function Might act as an inhibitor of spontaneous calcium carbonate precipitation. May be associated with neuronal sprouting in brain, and with brain and pancreas regeneration
GO Classification
Function
binding
Cellular Location
  1. Secreted
Pathways
Gene Properties
Chromosome Location Chromosome:2
Locus 2p12
SNPs REG1A
Gene Sequence
>501 bp
ATGGCTCAGACCAGCTCATACTTCATGCTGATCTCCTGCCTGATGTTTCTGTCTCAGAGC
CAAGGCCAAGAGGCCCAGACAGAGTTGCCCCAGGCCCGGATCAGCTGCCCAGAAGGCACC
AATGCCTATCGCTCCTACTGCTACTACTTTAATGAAGACCGCGAGACCTGGGTTGATGCA
GATCTCTATTGCCAGAACATGAATTCGGGCAACCTGGTGTCTGTGCTCACCCAGGCCGAG
GGTGCCTTTGTGGCCTCACTGATTAAGGAGAGTGGCACTGATGACTTCAATGTCTGGATT
GGCCTCCATGACCCCAAAAAGAACCGCCGCTGGCACTGGAGCAGTGGGTCCCTGGTCTCC
TACAAGTCCTGGGGCATTGGAGCCCCAAGCAGTGTTAATCCTGGCTACTGTGTGAGCCTG
ACCTCAAGCACAGGATTCCAGAAATGGAAGGATGTGCCTTGTGAAGACAAGTTCTCCTTT
GTCTGCAAGTTCAAAAACTAG
Protein Properties
Number of Residues 166
Molecular Weight 18730.8
Theoretical pI 5.73
Pfam Domain Function
Signals
  • ["1-22"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>Lithostathine-1-alpha
MAQTSSYFMLISCLMFLSQSQGQEAQTELPQARISCPEGTNAYRSYCYYFNEDRETWVDA
DLYCQNMNSGNLVSVLTQAEGAFVASLIKESGTDDFNVWIGLHDPKKNRRWHWSSGSLVS
YKSWGIGAPSSVNPGYCVSLTSSTGFQKWKDVPCEDKFSFVCKFKN
GenBank ID Protein 5764555
UniProtKB/Swiss-Prot ID P05451
UniProtKB/Swiss-Prot Entry Name REG1A_HUMAN
PDB IDs
GenBank Gene ID AF172331
GeneCard ID REG1A
GenAtlas ID REG1A
HGNC ID HGNC:9951
References
General References Not Available