| Identification |
|---|
| HMDB Protein ID
| CDBP03177 |
| Secondary Accession Numbers
| Not Available |
| Name
| Calcipressin-1 |
| Description
| Not Available |
| Synonyms
|
- Adapt78
- Down syndrome critical region protein 1
- MCIP1
- Myocyte-enriched calcineurin-interacting protein 1
- Regulator of calcineurin 1
|
| Gene Name
| RCAN1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in calcium-mediated signaling |
| Specific Function
| Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development |
| GO Classification
|
| Process |
| intracellular signal transduction |
| second-messenger-mediated signaling |
| calcium-mediated signaling |
| biological regulation |
| regulation of biological process |
| regulation of cellular process |
| signal transduction |
|
| Cellular Location
|
Not Available
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:2 |
| Locus
| 21q22.1-q22.2|21q22.12 |
| SNPs
| RCAN1 |
| Gene Sequence
|
>759 bp
ATGGAGGACGGCGTGGCCGGTCCCCAGCTCGGGGCCGCGGCGGAGGCGGCGGAGGCGGCC
GAGGCGCGAGCGCGGCCCGGGGTGACGCTGCGGCCCTTCGCGCCCCTCTCGGGGGCGGCC
GAGGCGGACGAGGGCGGCGGCGACTGGAGCTTCATTGACTGCGAGATGGAGGAGGTGGAC
CTGCAGGACCTGCCCAGCGCCACCATCGCCTGTCACCTGGACCCGCGCGTGTTCGTGGAC
GGCCTGTGCCGGGCCAAATTTGAGTCCCTCTTTAGGACGTATGACAAGGACATCACCTTT
CAGTATTTTAAGAGCTTCAAACGAGTCAGAATAAACTTCAGCAACCCCTTCTCCGCAGCA
GATGCCAGGCTCCAGCTGCATAAGACTGAGTTTCTGGGAAAGGAAATGAAGTTATATTTT
GCTCAGACCTTACACATAGGAAGCTCACACCTGGCTCCGCCAAATCCAGACAAGCAGTTT
CTGATCTCCCCTCCCGCCTCTCCGCCAGTGGGATGGAAACAAGTGGAAGATGCGACCCCA
GTCATAAACTATGATCTCTTATATGCCATCTCCAAGCTGGGGCCAGGGGAAAAGTATGAA
TTGCACGCAGCGACTGACACCACTCCCAGCGTGGTGGTCCATGTATGTGAGAGTGATCAA
GAGAAGGAGGAAGAAGAGGAAATGGAAAGAATGAGGAGACCTAAGCCAAAAATTATCCAG
ACCAGGAGGCCGGAGTACACGCCGATCCACCTCAGCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 252 |
| Molecular Weight
| 28078.4 |
| Theoretical pI
| 4.86 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Calcipressin-1
MEDGVAGPQLGAAAEAAEAAEARARPGVTLRPFAPLSGAAEADEGGGDWSFIDCEMEEVD
LQDLPSATIACHLDPRVFVDGLCRAKFESLFRTYDKDITFQYFKSFKRVRINFSNPFSAA
DARLQLHKTEFLGKEMKLYFAQTLHIGSSHLAPPNPDKQFLISPPASPPVGWKQVEDATP
VINYDLLYAISKLGPGEKYELHAATDTTPSVVVHVCESDQEKEEEEEMERMRRPKPKIIQ
TRRPEYTPIHLS
|
| External Links |
|---|
| GenBank ID Protein
| 33620725 |
| UniProtKB/Swiss-Prot ID
| P53805 |
| UniProtKB/Swiss-Prot Entry Name
| RCAN1_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_004414.5 |
| GeneCard ID
| RCAN1 |
| GenAtlas ID
| RCAN1 |
| HGNC ID
| HGNC:3040 |
| References |
|---|
| General References
| Not Available |