Identification
HMDB Protein ID CDBP03170
Secondary Accession Numbers Not Available
Name Salivary acidic proline-rich phosphoprotein 1/2
Description Not Available
Synonyms
  1. Db-F
  2. Db-s
  3. PIF-F
  4. PIF-S
  5. PRP-1/PRP-2
  6. PRP-3/PRP-4
  7. Pa
  8. Parotid acidic protein
  9. Parotid double-band protein
  10. Parotid isoelectric focusing variant protein
  11. Parotid proline-rich protein 1/2
  12. Peptide P-C
  13. Pr1/Pr2
  14. Protein A
  15. Protein C
  16. Salivary acidic proline-rich phosphoprotein 1/2
  17. Salivary acidic proline-rich phosphoprotein 3/4
Gene Name PRH1
Protein Type Enzyme
Biological Properties
General Function Involved in protein binding
Specific Function PRP's act as highly potent inhibitors of crystal growth of calcium phosphates. They provide a protective and reparative environment for dental enamel which is important for the integrity of the teeth
GO Classification Not Available
Cellular Location
  1. Secreted
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 12p13.2
SNPs PRH1
Gene Sequence
>501 bp
ATGCTTCTGATTCTGCTGTCAGTGGCCCTGCTGGCCTTCAGCTCAGCTCAGGACTTAGAT
GAAGATGTCAGCCAAGAAGACGTTCCCTTGGTAATATCAGATGGAGGAGACTCTGAGCAG
TTCATAGATGAGGAGCGTCAGGGACCACCTTTGGGAGGACAGCAATCTCAACCCTCTGCT
GGTGATGGGAACCAGGATGATGGCCCTCAGCAGGGACCACCCCAACAAGGAGGCCAGCAG
CAACAAGGTCCACCACCTCCTCAGGGAAAGCCACAAGGACCACCCCAACAGGGAGGCCAT
CCCCCTCCTCCTCAAGGAAGGCCACAAGGACCACCCCAACAGGGAGGCCATCCCCGTCCT
CCTCGAGGAAGGCCACAAGGACCACCCCAACAGGGAGGCCATCAGCAAGGTCCTCCCCCA
CCTCCTCCTGGAAAGCCCCAGGGACCACCTCCCCAAGGGGGCCGCCCACAAGGACCTCCA
CAGGGGCAGTCTCCTCAGTAA
Protein Properties
Number of Residues 166
Molecular Weight 17016.5
Theoretical pI 4.43
Pfam Domain Function Not Available
Signals
  • ["1-16"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>Salivary acidic proline-rich phosphoprotein 1/2
MLLILLSVALLAFSSAQDLDEDVSQEDVPLVISDGGDSEQFIDEERQGPPLGGQQSQPSA
GDGNQDDGPQQGPPQQGGQQQQGPPPPQGKPQGPPQQGGHPPPPQGRPQGPPQQGGHPRP
PRGRPQGPPQQGGHQQGPPPPPPGKPQGPPPQGGRPQGPPQGQSPQ
GenBank ID Protein 66267613
UniProtKB/Swiss-Prot ID P02810
UniProtKB/Swiss-Prot Entry Name PRPC_HUMAN
PDB IDs Not Available
GenBank Gene ID BC095488
GeneCard ID PRH1
GenAtlas ID PRH1
HGNC ID HGNC:9366
References
General References Not Available