Identification
HMDB Protein ID CDBP03145
Secondary Accession Numbers Not Available
Name Protocadherin gamma-C5
Description Not Available
Synonyms
  1. PCDH-gamma-C5
Gene Name PCDHGC5
Protein Type Metal Binding
Biological Properties
General Function Involved in calcium ion binding
Specific Function Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain
GO Classification
Component
membrane
cell part
plasma membrane
Function
ion binding
cation binding
metal ion binding
binding
calcium ion binding
Process
cell adhesion
cellular process
cell-cell adhesion
homophilic cell adhesion
Cellular Location
  1. Cell membrane
  2. Single-pass type I membrane protein
Pathways
Gene Properties
Chromosome Location Chromosome:5
Locus 5q31
SNPs PCDHGC5
Gene Sequence
>2835 bp
ATGGGGCCCAAGACACTCCCACAGCTCGCTGGGAAATGGCAAGTGCTGTGCATGTTGTCC
TTGTGCTGCTGGGGCTGGGTGTCTGGGCAGCTTCGTTACTCAGTGGTGGAGGAGTCTGAG
CCGGGGACGCTGGTGGGGAATGTTGCTCAGGATCTGGGCTTAAAGATGACAGATCTGTTG
AGCCGGCGGCTGCAATTGGGCTCTGAGGAGAATGGGCGCTATTTTTCCCTGAGCTTGATG
AGTGGTGCCCTGGCAGTGAATCAAAAGATTGACCGAGAAAGCCTATGTGGAGCCAGCACC
AGCTGCCTGCTGCCAGTGCAGGTGGTGACTGAACACCCCCTGGAGCTAATCCGTGTAGAG
GTAGAGATCCTGGATCTCAATGACAACTCTCCTAGCTTTGCCACCCCTGAGCGAGAGATG
CGCATCTCAGAATCAGCAGCATCTGGGGCACGATTCCCACTGGACAGTGCCCAGGATCCG
GATGTGGGCACCAATACTGTGAGCTTTTACACTCTAAGCCCCAACAGCCACTTCTCTCTG
AATGTGAAGACCCTAAAAGATGGGAAGCCATTCCCAGAGCTGGTGCTAGAGCAGCAGCTG
GATCGTGAAGCCCAGGCAAGACATCAGCTGGTGCTTACTGCTGTGGATGGGGGGACCCCA
GCCCGCTCAGGGACCACCCTTATCTCTGTCATCGTGCTGGACATCAATGATAATGCTCCA
ACCTTCCAATCCTCAGTTCTACGTGTGGGAATCCCAGAGAATGCACCCATTGGTACTCTG
CTGCTCCGCCTCAATGCCACTGATCCAGACGAGGGCACCAACGGCCAACTAGACTATTCT
TTTGGAGACCACACATCTGAGGCAGTGCGGAACCTCTTTGGCCTAGACCCTAGCAGTGGG
GCAATCCATGTGTTGGGTCCCATAGACTTTGAGGAGTCACGTTTCTATGAAATTCATGCA
AGAGCCCGTGACCAGGGACAGCCTGCCATGGAGGGCCACTGTGTGATTCAAGTGGATGTG
GGGGATGTCAATGACAATGCCCCAGAGGTGCTATTGGCCTCTTTGGCCAACCCTGTCCTA
GAGAGCACACCAGTGGGCACAGTAGTGGGGTTGTTTAATGTGCGAGACCGGGACTCAGGT
AGAAATGGTGAAGTGAGCCTTGATATCTCTCCGGACCTGCCATTTCAGATTAAGCCTTCT
GAGAACCACTACTCGCTGCTAACCAGCCAGCCTTTGGACCGGGAGGCCACATCCCACTAT
ATCATCGAGCTGCTGGCCAGCGATGCTGGTTCACCTTCCCTACACAAACATCTCACCATC
AGGCTCAACATTTCAGATGTCAATGACAATGCACCCCGCTTCAACCAGCAGCTTTACACT
GCTTACATCCTAGAAAACCGGCCTCCGGGCTCCCTTCTTTGCACTGTGGCTGCCTCAGAT
CCAGACACTGGGGATAATGCCCGCCTCACCTACTCCATTGTAGGAAATCAGGTTCAGGGA
GCCCCAGCCTCCTCCTTTGTGTATGTCAACCCAGAGGATGGACGGATCTTTGCCCAGCGT
ACCTTTGACTATGAATTGCTGCAGATGCTGCAGATTGTGGTGGGGGTTCGAGACTCCGGC
TCTCCCCCATTGCATGCCAACACATCTCTGCATGTGTTTGTCCTAGACGAGAATGATAAT
GCCCCAGCTGTGCTGCACCCACGGCCAGACTGGGAACACTCAGCCCCCCAGCGTCTCCCT
CGCTCTGCTCCTCCTGGCTCCTTGGTCACCAAGGTGACAGCCGTGGATGCTGATGCAGGC
CACAATGCGTGGCTCTCCTACTCACTGTTGCCACAGTCCACAGCCCCAGGACTGTTCCTC
GTGTCTACACACACTGGTGAGGTGCGCACAGCCCGGGCCTTACTGGAGGATGACTCTGAC
ACCCAGCAGGTGGTGGTCCTGGTGAGGGACAATGGTGACCCTTCACTCTCCTCCACAGCC
ACAGTGCTGCTGGTTCTGGAGGATGAGGACCCTGAGGAAATGCCCAAATCCAGTGACTTC
CTCATACACCCTCCTGAGCGTTCAGACCTTACCCTTTACCTCATTGTGGCTCTAGCGACC
GTCAGTCTCTTATCCCTAGTCACCTTCACCTTTCTGTCAGCGAAGTGCCTTCAGGGAAAC
GCAGACGGGGACGGGGGTGGAGGGCAGTGCTGCAGGCGCCAGGACTCACCCTCCCCGGAC
TTCTATAAGCAGTCCAGCCCCAACCTGCAGGTGAGCTCGGACGGCACGCTCAAGTACATG
GAGGTGACGCTGCGGCCCACAGACTCGCAGAGCCACTGCTACAGGACGTGCTTTTCACCG
GCCTCGGACGGCAGTGACTTCACTTTTCTAAGACCCCTCAGCGTTCAGCAGCCCACAGCT
CTGGCGCTGGAGCCTGACGCCATCCGGTCCCGCTCTAATACGCTGCGGGAGCGGAGCCAG
CAAGCCCCGCCCAACACGGACTGGCGTTTCTCTCAGGCCCAGAGACCCGGCACCAGCGGC
TCCCAAAATGGCGATGACACCGGCACCTGGCCCAACAACCAGTTTGACACAGAGATGCTG
CAAGCCATGATCTTGGCGTCCGCCAGTGAAGCTGCTGATGGGAGCTCCACCCTGGGAGGG
GGTGCCGGCACCATGGGATTGAGCGCCCGCTACGGACCCCAGTTCACCCTGCAGCACGTG
CCCGACTACCGCCAGAATGTCTACATCCCAGGCAGCAATGCCACACTGACCAACGCAGCT
GGCAAGCGGGATGGCAAGGCCCCAGCAGGTGGCAATGGCAACAAGAAGAAGTCGGGCAAG
AAGGAGAAGAAGTAA
Protein Properties
Number of Residues 944
Molecular Weight 101919.7
Theoretical pI 4.63
Pfam Domain Function
Signals
  • ["1-29"]
Transmembrane Regions
  • ["694-714"]
Protein Sequence
>Protocadherin gamma-C5
MGPKTLPQLAGKWQVLCMLSLCCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLL
SRRLQLGSEENGRYFSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVE
VEILDLNDNSPSFATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSL
NVKTLKDGKPFPELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAP
TFQSSVLRVGIPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSG
AIHVLGPIDFEESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVL
ESTPVGTVVGLFNVRDRDSGRNGEVSLDISPDLPFQIKPSENHYSLLTSQPLDREATSHY
IIELLASDAGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASD
PDTGDNARLTYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSG
SPPLHANTSLHVFVLDENDNAPAVLHPRPDWEHSAPQRLPRSAPPGSLVTKVTAVDADAG
HNAWLSYSLLPQSTAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTA
TVLLVLEDEDPEEMPKSSDFLIHPPERSDLTLYLIVALATVSLLSLVTFTFLSAKCLQGN
ADGDGGGGQCCRRQDSPSPDFYKQSSPNLQVSSDGTLKYMEVTLRPTDSQSHCYRTCFSP
ASDGSDFTFLRPLSVQQPTALALEPDAIRSRSNTLRERSQQAPPNTDWRFSQAQRPGTSG
SQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHV
PDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
GenBank ID Protein 5456984
UniProtKB/Swiss-Prot ID Q9Y5F6
UniProtKB/Swiss-Prot Entry Name PCDGM_HUMAN
PDB IDs Not Available
GenBank Gene ID AF152339
GeneCard ID PCDHGC5
GenAtlas ID PCDHGC5
HGNC ID HGNC:8718
References
General References Not Available