| Identification |
|---|
| HMDB Protein ID
| CDBP03140 |
| Secondary Accession Numbers
| Not Available |
| Name
| Protocadherin gamma-B5 |
| Description
| Not Available |
| Synonyms
|
- PCDH-gamma-B5
|
| Gene Name
| PCDHGB5 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain |
| GO Classification
|
| Component |
| membrane |
| cell part |
| plasma membrane |
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| calcium ion binding |
| Process |
| cell-cell adhesion |
| homophilic cell adhesion |
| cell adhesion |
| cellular process |
|
| Cellular Location
|
- Cell membrane
- Single-pass type I membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:5 |
| Locus
| 5q31 |
| SNPs
| PCDHGB5 |
| Gene Sequence
|
>2772 bp
ATGGGGAGCGGCGCCGGGGAGCTGGGCCGGGCTGAGAGGCTGCCAGTGCTCTTTCTCTTC
CTGCTGTCTTTGTTCTGCCCGGCGCTCTGTGAGCAGATCCGCTACAGGATTCCCGAGGAA
ATGCCCAAGGGCTCCGTAGTGGGGAACCTCGCCACGGACCTGGGGTTCAGCGTCCAGGAG
TTACCGACTCGAAAACTGCGCGTCAGTTCGGAGAAGCCTTACTTCACCGTGAGCGCAGAG
AGCGGGGAGTTGCTTGTGAGCAGCAGGCTAGACAGGGAGGAGATATGCGGGAAGAAGCCA
GCTTGTGCTCTGGAATTTGAGGCTGTTGCTGAAAATCCACTGAACTTTTATCACGTGAAT
GTGGAGATCGAGGACATTAATGACCACACGCCAAAATTCACGCAAAATTCCTTTGAGCTG
CAAATAAGTGAGTCTGCACAGCCTGGCACAAGATTTATACTAGAAGTAGCAGAAGATGCA
GATATTGGCTTAAACTCTCTGCAGAAGTATAAACTCTCTCTTAACCCAAGTTTCTCATTA
ATAATTAAGGAGAAACAGGATGGTAGTAAATACCCGGAACTGGCACTGGAGAAAACCTTA
GACCGGGAACAACAGAGTTACCATCGTTTAGTCCTGACTGCCTTGGACGGTGGACATCCA
CCCCTAAGCGGCACCACTGAGCTCCGGATCCAGGTAACCGACGCCAATGATAATCCCCCG
GTATTCAACCGAGACGTGTACAGAGTCAGCCTTCGGGAAAACGTGCCACCAGGCACCACT
GTGTTGCAAGTGTCAGCCACTGACCAAGACGAGGGCATCAACTCAGAAATTACTTATTCC
TTCTACAGAACCGGGCAAATCTTTAGTCTGAATTCAAAGAGCGGAGAAATTACCACTCAA
AAGAAACTGGATTTTGAAGAGACCAAGGAATATTCAATGGTTGTAGAAGGGAGGGATGGT
GGTGGACTGGTTGCACAATGTACAGTTGAAATTAATATTCAAGATGAAAATGACAATAGC
CCAGAAGTTACATTCCATTCTCTACTTGAAATGATTCTGGAAAACGCGGTGCCTGGAACA
CTAATTGCTTTGATCAAAATACATGACCAAGATTCTGGGGAAAATGGGGAGGTTAATTGT
CAATTACAAGGCGAAGTCCCTTTTAAGATTATCTCTTCATCCAAAAATTCGTATAAGTTG
GTAACAGATGGAACCCTAGACCGAGAGCAAACCCCGGAGTACAATGTCACCATCACAGCC
ACAGACAGGGGCAAGCCGCCCCTCTCCTCCAGCATAAGCGTCATCCTACATATCAGAGAC
GTCAACGATAACGCTCCGGTTTTCCACCAGGCGTCCTACTTAGTCAGTGTACCCGAAAAC
AACCCTCCTGGGGCCTCCATCGCGCAAGTCTGCGCCTCGGACCTGGACTTGGGGTTGAAC
GGCCAAGTCTCCTACTCTATCATGGCCAGCGACCTAGAGCCTCTGGCACTGGCCTCTTAC
GTGTCCATGAGCGCGCAAAGTGGGGTGGTGTTCGCGCAGCGCGCCTTTGACTACGAGCAG
CTGCGCACCTTCGAACTCACACTACAGGCCCGCGACCAGGGCTCGCCTGCGCTCAGCGCA
AACGTGAGCCTGCGCGTGTTGGTGGGCGACCGAAACGACAACGCACCGCGGGTGCTGTAC
CCCGCGCTGGGTCCCGACGGCTCTGCGCTCTTCGATATGGTGCCGCGCGCTGCAGAGCCC
GGCTACCTGGTGACCAAGGTAGTGGCCGTGGACGCAGACTCAGGACACAACGCCTGGCTG
TCCTACCACGTGCTGCAGGCTAGCGAGCCCGGGCTCTTCAGCCTGGGGCTGCGCACAGGA
GAGGTGCGCACAGCGCGTGCCTTGGGCGACAGGGACGCGGCCCGCCAGCGCCTGCTGGTT
GCTGTGCGTGATGGTGGACAGCCGCCACTCTCCGCCACCGCCACGCTGCACTTGGTCTTT
GCTGACAGCTTGCAGGAGGTGCTGCCGGATATCACTGACCGCCCTGTACCCTCTGACCCC
CAGGCTGAGCTGCAGTTTTACCTAGTGGTGGCCTTGGCCTTGATCTCAGTGCTCTTCCTC
CTGGCCGTGATTCTGGCCGTTGCCTTGCGCCTGCGACGCTCCTCCAGCCCTGCCGCCTGG
AGCTGCTTCCAACCTGGTCTCTGTGTCAAGTCTGGACCTGTGGTTCCCCCCAACTACAGT
CAGGGGACTTTGCCTTATTCCTACAACCTATGTGTTGCACATACAGGAAAGACGGAGTTT
AATTTCCTAAAATGTAGTGAGCAATTGAGTTCAGGACAAGACATACTTTGTGGTGATTCA
TCTGGGGCCTTATTTCCACTTTGTAATTCCAGCGAGTCGACTTCCCATCCTGAGTTGCAA
GCCCCGCCCAACACGGACTGGCGTTTCTCTCAGGCCCAGAGACCCGGCACCAGCGGCTCC
CAAAATGGCGATGACACCGGCACCTGGCCCAACAACCAGTTTGACACAGAGATGCTGCAA
GCCATGATCTTGGCGTCCGCCAGTGAAGCTGCTGATGGGAGCTCCACCCTGGGAGGGGGT
GCCGGCACCATGGGATTGAGCGCCCGCTACGGACCCCAGTTCACCCTGCAGCACGTGCCC
GACTACCGCCAGAATGTCTACATCCCAGGCAGCAATGCCACACTGACCAACGCAGCTGGC
AAGCGGGATGGCAAGGCCCCAGCAGGTGGCAATGGCAACAAGAAGAAGTCGGGCAAGAAG
GAGAAGAAGTAA
|
| Protein Properties |
|---|
| Number of Residues
| 923 |
| Molecular Weight
| 99874.1 |
| Theoretical pI
| 4.67 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Protocadherin gamma-B5
MGSGAGELGRAERLPVLFLFLLSLFCPALCEQIRYRIPEEMPKGSVVGNLATDLGFSVQE
LPTRKLRVSSEKPYFTVSAESGELLVSSRLDREEICGKKPACALEFEAVAENPLNFYHVN
VEIEDINDHTPKFTQNSFELQISESAQPGTRFILEVAEDADIGLNSLQKYKLSLNPSFSL
IIKEKQDGSKYPELALEKTLDREQQSYHRLVLTALDGGHPPLSGTTELRIQVTDANDNPP
VFNRDVYRVSLRENVPPGTTVLQVSATDQDEGINSEITYSFYRTGQIFSLNSKSGEITTQ
KKLDFEETKEYSMVVEGRDGGGLVAQCTVEINIQDENDNSPEVTFHSLLEMILENAVPGT
LIALIKIHDQDSGENGEVNCQLQGEVPFKIISSSKNSYKLVTDGTLDREQTPEYNVTITA
TDRGKPPLSSSISVILHIRDVNDNAPVFHQASYLVSVPENNPPGASIAQVCASDLDLGLN
GQVSYSIMASDLEPLALASYVSMSAQSGVVFAQRAFDYEQLRTFELTLQARDQGSPALSA
NVSLRVLVGDRNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWL
SYHVLQASEPGLFSLGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLVF
ADSLQEVLPDITDRPVPSDPQAELQFYLVVALALISVLFLLAVILAVALRLRRSSSPAAW
SCFQPGLCVKSGPVVPPNYSQGTLPYSYNLCVAHTGKTEFNFLKCSEQLSSGQDILCGDS
SGALFPLCNSSESTSHPELQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQ
AMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAG
KRDGKAPAGGNGNKKKSGKKEKK
|
| External Links |
|---|
| GenBank ID Protein
| 5456968 |
| UniProtKB/Swiss-Prot ID
| Q9Y5G0 |
| UniProtKB/Swiss-Prot Entry Name
| PCDGH_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF152334 |
| GeneCard ID
| PCDHGB5 |
| GenAtlas ID
| PCDHGB5 |
| HGNC ID
| HGNC:8712 |
| References |
|---|
| General References
| Not Available |