| Identification |
|---|
| HMDB Protein ID
| CDBP03138 |
| Secondary Accession Numbers
| Not Available |
| Name
| Protocadherin gamma-B3 |
| Description
| Not Available |
| Synonyms
|
- PCDH-gamma-B3
|
| Gene Name
| PCDHGB3 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain |
| GO Classification
|
| Component |
| membrane |
| cell part |
| plasma membrane |
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| calcium ion binding |
| Process |
| cell-cell adhesion |
| homophilic cell adhesion |
| cell adhesion |
| cellular process |
|
| Cellular Location
|
- Cell membrane
- Single-pass type I membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:5 |
| Locus
| 5q31 |
| SNPs
| PCDHGB3 |
| Gene Sequence
|
>2790 bp
ATGGGAAATAGCTCCGGATGGAGGGGCCCAGCAGGGCAGAGGCGAATGCTATTTCTCTTC
CTGCTCTCTTTGTTAGACCAGGTTCTCTCCGAACCGATCCGCTACGCTATTCCCGAGGAG
CTGGACAGGGGCTCGCTGGTAGGGAACCTCGCCAAGGACCTGGGGTTTGGCGTGGGGGAT
TTACCTACTAGGAACCTGCGGGTTATTGCAGAGAAGAAATTCTTTACCGTGAGCCCCGAA
AATGGGAACTTACTTGTGAGCGACCGTATAGACCGAGAGGAGATTTGTGGCAAGAAGTCG
ACGTGTGTTCTGGAATTTGAAATGGTTGCTGAAAAGCCTTTAAACTTTTTTCATGTAACT
GTGCTGATCCAGGATATTAACGACAACCCACCGACCTTTAGCCAAAATATCACTGAGCTG
GAAATCAGCGAACTGGCTCTCACTGGAGCCACATTTGCCCTGGAATCTGCGCAAGATCCT
GATGTAGGTGTCAATTCGCTGCAGCAGTACTACCTCAGCCCTGATCCGCACTTCTCTTTG
ATTCAGAAGGAGAACCTGGATGGCAGTAGGTACCCAGAGCTAGTACTGAAAGCACCCCTG
GACAGGGAAGAGCAGCCACATCACCACCTGGTCCTCACAGCTGTGGATGGGGGCGAGCCC
TCCAGAAGCTGTACCACCCAGATCAGGGTAATTGTCGCAGATGCAAATGATAACCCCCCA
GTATTTACTCAGGACATGTACAGGGTCAATGTTGCAGAGAACCTGCCCGCTGGCTCCTCC
GTATTAAAAGTGATGGCCATTGACATGGATGAGGGCATCAATGCCGAAATCATCTATGCC
TTCATCAATATTGGCAAGGAAGTGAGACAACTGTTCAAGCTGGACAGTAAAACGGGGGAA
CTCACCACTATTGGAGAACTGGACTTTGAAGAGAGAGATAGCTACACAATTGGGGTGGAA
GCAAAGGATGGTGGACATCACACTGCATATTGTAAAGTACAGATAGATATTTCAGATGAA
AATGACAATGCCCCGGAGATAACCCTGGCTTCTGAATCCCAACATATACAAGAAGATGCT
GAGCTGGGGACTGCCGTTGCCCTGATCAAAACACATGATCTAGATTCTGGATTTAATGGA
GAAATCCTATGCCAACTAAAAGGAAACTTCCCCTTTAAAATCGTTCAAGATACCAAAAAC
ACATACAGGTTGGTGACAGATGGAGCCCTGGACCGGGAGCAGATCCCAGAATACAATGTG
ACGATCACAGCTACCGACAAAGGCAATCCACCGCTCTCCTCCAGCAAGACCATCACTCTG
CACATCCTTGATGTCAACGACAACGTTCCCGTTTTCCACCAGGCCTCCTACACCGTGCAT
GTAGCTGAGAACAATCCGCCTGGAGCCTCCATTGCGCATGTCAGAGCCTCGGATCCCGAC
TTGGGACCTAATGGCCTTGTCTCCTACTACATCGTGGCCAGTGACCTGGAGCCGCGGGAG
CTGTCGTCCTACGTGTCCGTGAGCGCGCGGAGCGGGGTGGTGTTCGCGCAGCGAGCCTTC
GACCACGAGCAGCTGCGTGCCTTCGAGCTCACTCTGCAGGCCCGCGACCAGGGCTCGCCT
ACGCTCAGCGCCAACGTGAGCCTGCGCGTGTTGGTGGACGACCGCAACGACAATGCACCG
CTGGTGCTGTACCCAGCTCTGGGGCCCGAAGGCTCTGCGCTCTTCGATATGGTGCCGCGC
TCTGCAGAGCCTGGCTACCTGGTGACCAAGGTGGTGGCGGTGGACGCAGACTCGGGATAC
AACGCCTGGCTGTCCTACCACATTGTGCAGGCCAGCGAGCCCGGGCTGTTCAGCCTGGGC
CTGCGCACGGGTGAGGTGCGCACGGCGCGTACCTTGGGCGACAGGGAGGCCGCCCGCCAG
CGCCTGCTGGTCACTGTGCGTGATGGAGGACAGCAGCCTCTTTCAGCCACCGTCATGCTG
CACCTAATCTTCGCAGATAGCTTGCAAGAGATACAACCTGACCTTAGCGACCGCCCCACT
CCCTCTGACCCTCAGGCGGAGCTACAGTTTCACCTAGTAGTGGCGTTGGCCTTGATCTCA
GTGCTCTTCCTCCTCGCGGTGATTCTGGCAATCTCCCTGCGCCTGCGATGCTCCTCCAGA
CCCGCCACTGAGGGCTACTTTCAGCCTGGTGTCTGCTTCAAGACTGTACCTGGAGTTCTC
CCCACCTACAGCGAAAGGACTTTGCCTTATTCCTACAATCCGTGTGCTGCCTCACATTCC
TCAAACACCGAGTTTAAATTTCTCAATATAAAGGCTGAAAATGCTGCACCACAAGATCTT
CTATGTGATGAAGCCTCTTGGTTTGAAAGTAATGACAATCCAGAAATGCCTTCTAATTCA
GGCAATTTGCAAAAGCAAGCCCCGCCCAACACGGACTGGCGTTTCTCTCAGGCCCAGAGA
CCCGGCACCAGCGGCTCCCAAAATGGCGATGACACCGGCACCTGGCCCAACAACCAGTTT
GACACAGAGATGCTGCAAGCCATGATCTTGGCGTCCGCCAGTGAAGCTGCTGATGGGAGC
TCCACCCTGGGAGGGGGTGCCGGCACCATGGGATTGAGCGCCCGCTACGGACCCCAGTTC
ACCCTGCAGCACGTGCCCGACTACCGCCAGAATGTCTACATCCCAGGCAGCAATGCCACA
CTGACCAACGCAGCTGGCAAGCGGGATGGCAAGGCCCCAGCAGGTGGCAATGGCAACAAG
AAGAAGTCGGGCAAGAAGGAGAAGAAGTAA
|
| Protein Properties |
|---|
| Number of Residues
| 929 |
| Molecular Weight
| 101203.4 |
| Theoretical pI
| 4.62 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Protocadherin gamma-B3
MGNSSGWRGPAGQRRMLFLFLLSLLDQALSEPIRYAIPEELDRGSLVGNLAKDLGFGVGD
LPTRNLRVIAEKKFFTVSPENGNLLVSDRIDREEICGKKSTCVLEFEMVAEKPLNFFHVT
VLIQDINDNPPTFSQNITELEISELALTGATFALESAQDPDVGVNSLQQYYLSPDPHFSL
IQKENLDGSRYPELVLKAPLDREEQPHHHLVLTAVDGGEPSRSCTTQIRVIVADANDNPP
VFTQDMYRVNVAENLPAGSSVLKVMAIDMDEGINAEIIYAFINIGKEVRQLFKLDSKTGE
LTTIGELDFEERDSYTIGVEAKDGGHHTAYCKVQIDISDENDNAPEITLASESQHIQEDA
ELGTAVALIKTHDLDSGFNGEILCQLKGNFPFKIVQDTKNTYRLVTDGALDREQIPEYNV
TITATDKGNPPLSSSKTITLHILDVNDNVPVFHQASYTVHVAENNPPGASIAHVRASDPD
LGPNGLVSYYIVASDLEPRELSSYVSVSARSGVVFAQRAFDHEQLRAFELTLQARDQGSP
TLSANVSLRVLVDDRNDNAPLVLYPALGPEGSALFDMVPRSAEPGYLVTKVVAVDADSGY
NAWLSYHIVQASEPGLFSLGLRTGEVRTARTLGDREAARQRLLVTVRDGGQQPLSATVML
HLIFADSLQEIQPDLSDRPTPSDPQAELQFHLVVALALISVLFLLAVILAISLRLRCSSR
PATEGYFQPGVCFKTVPGVLPTYSERTLPYSYNPCAASHSSNTEFKFLNIKAENAAPQDL
LCDEASWFESNDNPEMPSNSGNLQKQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQF
DTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNAT
LTNAAGKRDGKAPAGGNGNKKKSGKKEKK
|
| External Links |
|---|
| GenBank ID Protein
| 5456961 |
| UniProtKB/Swiss-Prot ID
| Q9Y5G1 |
| UniProtKB/Swiss-Prot Entry Name
| PCDGF_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF152332 |
| GeneCard ID
| PCDHGB3 |
| GenAtlas ID
| PCDHGB3 |
| HGNC ID
| HGNC:8710 |
| References |
|---|
| General References
| Not Available |