Identification
HMDB Protein ID CDBP03134
Secondary Accession Numbers Not Available
Name Protocadherin gamma-A11
Description Not Available
Synonyms
  1. PCDH-gamma-A11
Gene Name PCDHGA11
Protein Type Metal Binding
Biological Properties
General Function Involved in calcium ion binding
Specific Function Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain
GO Classification
Component
membrane
cell part
plasma membrane
Function
ion binding
cation binding
metal ion binding
binding
calcium ion binding
Process
cell-cell adhesion
homophilic cell adhesion
cell adhesion
cellular process
Cellular Location
  1. Cell membrane
  2. Single-pass type I membrane protein
Pathways
Gene Properties
Chromosome Location Chromosome:5
Locus 5q31
SNPs PCDHGA11
Gene Sequence
>2808 bp
ATGGCGAATCGGCTACAGCGCGGGGACCGCAGTCGGCTGCTGCTGCTGCTGTGCATTTTC
CTGGGGACGCTGCGGGGGTTCCGGGCCAGGCAGATCCGATATTCGGTGCCAGAAGAGACC
GAAAAGGGCTCCTTCGTGGGCAATATCTCCAAGGACCTGGGGCTGGAGCCCCGGGAGCTG
GCGAAGCGCGGAGTCCGCATCGTCTCCAGAGGGAAGACACAGCTTTTCGCTGTGAATCCG
CGAAGCGGCAGCTTGATCACGGCAGGCAGGATAGACCGGGAGGAGCTCTGTGAGACGGTG
TCCTCCTGTTTTTTAAATATGGAACTTCTCGTGGAAGACACCTTGAAGATTTACGGAGTG
GAGGTGGAAATAATAGATATTAATGATAACGCCCCCAGCTTCCAGGAGGACGAAGTGGAG
ATAAAAGTCAGTGAGCACGCAATTCCTGGGGCGCGATTTGCTCTTCCTAATGCTAGGGAT
CCAGATGTGGGCGTGAACTCCCTCCAGAGCTACCAGCTCAGCCCTAATAATTACTTTTCC
TTGCAACTGCGGGGCAGAACGGATGGGGCCAAGAATCCAGAGCTAGTACTGGAGGGAAGC
CTGGACCGAGAGAAAGAGGCTGCTCACCTGCTCCTCCTCACAGCTTTAGATGGAGGCGAT
CCCATCCGAAAGGGCGCAGTTCCCATTCGTGTGGTGGTCCTCGATGTAAATGATCACATC
CCAATGTTTACACAGTCCGTATATCGCGTGAGTGTTCCAGAAAACATCAGCTCCGGAACT
CGGGTGCTGATGGTTAATGCAACGGATCCAGACGAGGGAATCAACGGGGAAGTAATGTAT
TCATTTCGGAACATGGAAAGCAAGGCTTCTGAAATATTCCAATTGGATTCACAAACTGGA
GAAGTTCAAGTACGGGGGTCTCTGGATTTTGAAAAATATAGATTCTATGAGATGGAAATT
CAAGGCCAAGATGGTGGAGGTCTCTTTACCACCACGACGATGTTGATCACTGTTGTGGAT
GTGAATGATAACGCTCCAGAAATAACTATCACCTCTTCTATTAATTCAATTCTGGAAAAC
TCTCCTCCAGGTACAGTGATTGCTCTTCTAAATGTGCAAGATCAAGATTCTGGAGAAAAT
GGTCAAGTCTCCTGTTTTATTCCTAACCACCTGCCTTTTAAATTAGAAAAGACTTATGGA
AATTATTACAAATTGATAACAAGCAGAGTGCTGGACAGGGAGTTGGTCCAGAGCTACAAT
ATAACGTTGACAGCCACAGACCAGGGAAGCCCGCCTTTGTCTGCAGAAACTCATGTCTGG
CTGAATGTGGCAGATGACAACGATAACCCTCCCGTTTTTCCTCACTCCTCTTACTCTGCC
TACATTCCCGAAAACAACCCCAGGGGTGCCTCCATCTTCTCAGTGACCGCCCTCGACCCG
GACAGCAAACAGAATGCCCTGGTCACTTACTCTCTGACGGATGACACTGTCCAGGGGGTG
CCTCTGTCCTCCTATGTCTCTATTAACTCCAACACTGGTGTTCTCTATGCCCTACAATCC
TTCGACTATGAGCAGTTTCGAGACTTAGAACTGAGAGTGATAGCACGTGACAGCGGGGAC
CCGCCCCTCAGCAGCAACGTGTCGCTGAGCCTGTTCGTGCTGGACCAGAACGACAATGCG
CCCGAGATCCTGTACCCTGCCCTCCCCACAGACGGCTCCACTGGCGTGGAGCTGGCGCCC
CGCTCTGCGGAACCTGGCTACCTGGTGACCAAGGTGGTTGCGGTGGACAAAGATTCAGGC
CAGAACGCCTGGCTGTCCTATCGCCTGCTTAAGGCCAGCGAGCCGGGACTCTTCGCGGTG
GGGGAGCACACGGGCGAGGTGCGTACAGCGCGGGCACTGCTGGACAGAGACGCGCTCAAG
CAGAGCCTCGTGGTGGCCGTCCAGGACCACGGCCAGCCCCCTCTCTCGGCCACCGTCACG
CTCACCGTGGCTGTGGCCGACAGCATCCCCGAAGTCCTGGCGGACCTCGGCAGCCTCGAG
TCTCTGGCTAACTCTGAAACCTCAGACCTCTCGCTGTACTTGGTGGTGGCGGTGGCCGCA
GTCTCCTGCATCTTCCTGGTCTTTGTCATCGTGCTGCTGGCACTCAGGCTGTGGCGCTGG
CATAAGTCACGCCTGCTGCAGGCTTCTGAAGGCGGGTTGGCAGGTATGCCCACGTCACAT
TTTGTAGGCGTGGACGGGGTACAGGCTTTCCTGCAAACCTATTCCCACGAGGTCTCTCTC
ATTGCGGACTCGCAGAAGAGTCACCTGATTTTCCCCCAGCCCAACTATGGGGACACGCTC
ATCAGCCAGGAGAGCTGTGAGAAAAGCGAGCCACTCTTGATAGCTGAAGACTCAGCTATC
ATTTTAGGCAAATGTGACCCGACAAGTAATCAGCAAGCCCCGCCCAACACGGACTGGCGT
TTCTCTCAGGCCCAGAGACCCGGCACCAGCGGCTCCCAAAATGGCGATGACACCGGCACC
TGGCCCAACAACCAGTTTGACACAGAGATGCTGCAAGCCATGATCTTGGCGTCCGCCAGT
GAAGCTGCTGATGGGAGCTCCACCCTGGGAGGGGGTGCCGGCACCATGGGATTGAGCGCC
CGCTACGGACCCCAGTTCACCCTGCAGCACGTGCCCGACTACCGCCAGAATGTCTACATC
CCAGGCAGCAATGCCACACTGACCAACGCAGCTGGCAAGCGGGATGGCAAGGCCCCAGCA
GGTGGCAATGGCAACAAGAAGAAGTCGGGCAAGAAGGAGAAGAAGTAA
Protein Properties
Number of Residues 935
Molecular Weight 101542.0
Theoretical pI 4.56
Pfam Domain Function
Signals
  • ["1-29"]
Transmembrane Regions
  • ["694-714"]
Protein Sequence
>Protocadherin gamma-A11
MANRLQRGDRSRLLLLLCIFLGTLRGFRARQIRYSVPEETEKGSFVGNISKDLGLEPREL
AKRGVRIVSRGKTQLFAVNPRSGSLITAGRIDREELCETVSSCFLNMELLVEDTLKIYGV
EVEIIDINDNAPSFQEDEVEIKVSEHAIPGARFALPNARDPDVGVNSLQSYQLSPNNYFS
LQLRGRTDGAKNPELVLEGSLDREKEAAHLLLLTALDGGDPIRKGAVPIRVVVLDVNDHI
PMFTQSVYRVSVPENISSGTRVLMVNATDPDEGINGEVMYSFRNMESKASEIFQLDSQTG
EVQVRGSLDFEKYRFYEMEIQGQDGGGLFTTTTMLITVVDVNDNAPEITITSSINSILEN
SPPGTVIALLNVQDQDSGENGQVSCFIPNHLPFKLEKTYGNYYKLITSRVLDRELVQSYN
ITLTATDQGSPPLSAETHVWLNVADDNDNPPVFPHSSYSAYIPENNPRGASIFSVTALDP
DSKQNALVTYSLTDDTVQGVPLSSYVSINSNTGVLYALQSFDYEQFRDLELRVIARDSGD
PPLSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDKDSG
QNAWLSYRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVT
LTVAVADSIPEVLADLGSLESLANSETSDLSLYLVVAVAAVSCIFLVFVIVLLALRLWRW
HKSRLLQASEGGLAGMPTSHFVGVDGVQAFLQTYSHEVSLIADSQKSHLIFPQPNYGDTL
ISQESCEKSEPLLIAEDSAIILGKCDPTSNQQAPPNTDWRFSQAQRPGTSGSQNGDDTGT
WPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYI
PGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
GenBank ID Protein 5456928
UniProtKB/Swiss-Prot ID Q9Y5H2
UniProtKB/Swiss-Prot Entry Name PCDGB_HUMAN
PDB IDs Not Available
GenBank Gene ID AF152320
GeneCard ID PCDHGA11
GenAtlas ID PCDHGA11
HGNC ID HGNC:8698
References
General References Not Available