| Identification |
|---|
| HMDB Protein ID
| CDBP03127 |
| Secondary Accession Numbers
| Not Available |
| Name
| Protocadherin gamma-A4 |
| Description
| Not Available |
| Synonyms
|
- PCDH-gamma-A4
|
| Gene Name
| PCDHGA4 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain |
| GO Classification
|
| Component |
| membrane |
| cell part |
| plasma membrane |
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| calcium ion binding |
| Process |
| cell adhesion |
| cellular process |
| cell-cell adhesion |
| homophilic cell adhesion |
|
| Cellular Location
|
- Cell membrane
- Single-pass type I membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:5 |
| Locus
| 5q31 |
| SNPs
| PCDHGA4 |
| Gene Sequence
|
>2796 bp
ATGGCGGCGCCTCCTGCTCGCCCAGACCACACCCGGCTGCTCCAGATCTGCCTTCTCCTG
GGGGTTCTGGTGGAAATCAGGGCCGAACAGATTCTCTACTCGGTGTTTGAGGAGCAGGAA
GAAGGCTCAGTGGTGGGCAACATCGCCAAGGACCTGGGGTTGGCGCCCCGGGAGCTGGCG
GAGCGCGGAGTCCGCATCGTCTCCAGAGGTAGGACGCAGCTTTTCGCCCTGAACCCGCGC
AGCGGCACCTTGGTCACCGCGGGTAGGATAGACAGGGAGGAGCTCTGCGACAGATCTCCA
AACTGTGTGACAAACCTGGAGATTCTTCTAGAAGATACAGTGAAGATTTTGCGGGTAGAG
GTGGAAATAATCGATGTTAATGATAACCCACCCAGTTTTGGGACAGAACAGAGGGAAATA
AAAGTTGCTGAAAATGAAAATCCTGGGGCAAGATTTCCTCTTCCTGAAGCTTTTGATCCG
GATGTAGGTGTAAACTCCCTGCAGGGTTACCAGCTCAACTCAAACGGTTACTTTTCCCTG
GACGTGCAAAGTGGGGCCGATGGGATTAAGTACCCAGAGCTGGTGCTGGAACGCGCTCTA
GATCGCGAGGAAGAGGCGGTTCACCACCTCGTTCTCACGGCCTTCGATGGAGGTGACCCG
GTTCGCTCTGGCACTGCCAGGATTCTCATAATACTTGTGGATACCAACGATAATGCTCCC
GTGTTCACTCAGCCCGAGTACCACGTAAGTGTTCGTGAGAACGTTCCTGTAGGCACTCGG
CTACTCACCGTAAAAGCCACTGATCCAGATGAAGGAGCCAATGGAGACGTGACGTATTCT
TTCCGGAAAGTAAGAGACAAAATATCACAGCTATTTCAGTTGAATTCTCTGAGTGGGGAT
ATAACAATATTGGGGGGTCTAGATTATGAGGACTCTGGATTCTATGACATAGATGTAGAA
GCCCATGATGGGCCTGGTCTCCGAGCTAGAAGCAAGGTACTGGTGACAGTTCTGGATGAA
AATGACAACGCACCAGAAGTCACAGTTACATCTCTCACCAGCTCAGTCCAGGAATCTTCT
TCCCCGGGTACAGTAATTGCACTTTTCAACGTGCATGACAGTGACTCAGGAGGAAATGGC
CTAGTCACATGTTCTATTCCAGATAATCTGCCATTCACACTTGAAAAGACCTATGGAAAT
TATTATCGGTTGTTGACACACAGAACACTGGACAGGGAAGAAGTCTCAGAATATAACATC
ACTGTAACTGCCACTGACCAGGGAACTCCTCCACTGTCTACAGAAACTCATATTTCACTG
CAAGTGATGGACATCAATGACAACCCACCCACTTTCCCTCATGCTTCCTACTCTGCTTAC
ATTCCTGAAAACAACCCCAGAGGAGCCTCCATCTTATCTATGACTGCTCAAGACCCTGAC
AGTGGTGACAATGCCCGAATCACTTACTCCCTGGCCGAAGACACCTTCCAGGGTGCACCT
CTGTCCTCCTATGTCTCCATCAACTCCAATACAGGGATCCTATATGCTCTTTGCTCCTTC
GACTATGAGCAGTTTAGAGACCTGCAGCTGCTGATGACAGCCAGTGACAGTGGAGACCCT
CCACTCAGCAGCAATGTGTCACTGAGCCTCTTTGTGCTGGACCAGAACGACAATGTCCCT
GAGATCCTGTACCCCACCTTCCCTACTGATGGCTCCACTGGTGTGGAGCTGGCACCCCGC
TCCGCAGATTCCGGCTACCTGGTGACCAAAGTGGTGGCAGTGGACAGAGACTCAGGTCAG
AATGCCTGGCTGTCCTACAGCCTACTCAAGTCCAGCGAGCCGGGACTATTTGCAGTGGGG
CTGCACACAGGCGAGGTGCGCACCGCACGGGCCCTGCTGGACAGAGACGCGCTCAAGCAG
AGGCTTGTAGTGGTCGTCCAGGACCATGGCCAGCCCCCTCTCTCGGCCACCGTCACACTC
ACTGTGGCTGTGGCCGACAGCATCCCAGATGTCCTGGCTGACTTGGGCAGCCTCAAGCCT
TCAGCAGACCCAGACGACTCGGGCCTCACACTCTATCTCGTGGTGGCAGTGGCCGCTGTC
TCCTGCGTCTTCCTGGCTTTTGTCACGGTGCTGCTAGCACTCAAGCTGAGACGCTGGCAC
AAGTCACGCCTGCTTCACGCTGAAGGCAGCAGGTTGGCAGGTGTGCCTGCCTCGCACTTT
GTGGGCGTGGACGGGGTTCGGGCTTTCCTGCAGACCTATTCCCACGAGGTCTCCCTCACC
GCGGACTCGCGGAAGAGTCACCTGATCTTCTCCCAACCCAGCTATGCAGACACGCTCATC
AGCCGGGAGAGTTGTGAGAAAAGCGAGCCTCTTCTGATAACTCAGGATTTACTTGAAACA
AAAGGAGACCCTAATCTTCAGCAAGCCCCGCCCAACACGGACTGGCGTTTCTCTCAGGCC
CAGAGACCCGGCACCAGCGGCTCCCAAAATGGCGATGACACCGGCACCTGGCCCAACAAC
CAGTTTGACACAGAGATGCTGCAAGCCATGATCTTGGCGTCCGCCAGTGAAGCTGCTGAT
GGGAGCTCCACCCTGGGAGGGGGTGCCGGCACCATGGGATTGAGCGCCCGCTACGGACCC
CAGTTCACCCTGCAGCACGTGCCCGACTACCGCCAGAATGTCTACATCCCAGGCAGCAAT
GCCACACTGACCAACGCAGCTGGCAAGCGGGATGGCAAGGCCCCAGCAGGTGGCAATGGC
AACAAGAAGAAGTCGGGCAAGAAGGAGAAGAAGTAA
|
| Protein Properties |
|---|
| Number of Residues
| 931 |
| Molecular Weight
| 100588.2 |
| Theoretical pI
| 4.48 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Protocadherin gamma-A4
MAAPPARPDHTRLLQICLLLGVLVEIRAEQILYSVFEEQEEGSVVGNIAKDLGLAPRELA
ERGVRIVSRGRTQLFALNPRSGTLVTAGRIDREELCDRSPNCVTNLEILLEDTVKILRVE
VEIIDVNDNPPSFGTEQREIKVAENENPGARFPLPEAFDPDVGVNSLQGYQLNSNGYFSL
DVQSGADGIKYPELVLERALDREEEAVHHLVLTAFDGGDPVRSGTARILIILVDTNDNAP
VFTQPEYHVSVRENVPVGTRLLTVKATDPDEGANGDVTYSFRKVRDKISQLFQLNSLSGD
ITILGGLDYEDSGFYDIDVEAHDGPGLRARSKVLVTVLDENDNAPEVTVTSLTSSVQESS
SPGTVIALFNVHDSDSGGNGLVTCSIPDNLPFTLEKTYGNYYRLLTHRTLDREEVSEYNI
TVTATDQGTPPLSTETHISLQVMDINDNPPTFPHASYSAYIPENNPRGASILSMTAQDPD
SGDNARITYSLAEDTFQGAPLSSYVSINSNTGILYALCSFDYEQFRDLQLLMTASDSGDP
PLSSNVSLSLFVLDQNDNVPEILYPTFPTDGSTGVELAPRSADSGYLVTKVVAVDRDSGQ
NAWLSYSLLKSSEPGLFAVGLHTGEVRTARALLDRDALKQRLVVVVQDHGQPPLSATVTL
TVAVADSIPDVLADLGSLKPSADPDDSGLTLYLVVAVAAVSCVFLAFVTVLLALKLRRWH
KSRLLHAEGSRLAGVPASHFVGVDGVRAFLQTYSHEVSLTADSRKSHLIFSQPSYADTLI
SRESCEKSEPLLITQDLLETKGDPNLQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNN
QFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSN
ATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
|
| External Links |
|---|
| GenBank ID Protein
| 5456940 |
| UniProtKB/Swiss-Prot ID
| Q9Y5G9 |
| UniProtKB/Swiss-Prot Entry Name
| PCDG4_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF152324 |
| GeneCard ID
| PCDHGA4 |
| GenAtlas ID
| PCDHGA4 |
| HGNC ID
| HGNC:8702 |
| References |
|---|
| General References
| Not Available |