| Identification |
|---|
| HMDB Protein ID
| CDBP03122 |
| Secondary Accession Numbers
| Not Available |
| Name
| Protocadherin alpha-C1 |
| Description
| Not Available |
| Synonyms
|
- PCDH-alpha-C1
|
| Gene Name
| PCDHAC1 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain |
| GO Classification
|
| Component |
| membrane |
| cell part |
| plasma membrane |
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| calcium ion binding |
| Process |
| homophilic cell adhesion |
| cell adhesion |
| cellular process |
| cell-cell adhesion |
|
| Cellular Location
|
- Cell membrane
- Single-pass type I membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:5 |
| Locus
| 5q31 |
| SNPs
| PCDHAC1 |
| Gene Sequence
|
>2892 bp
ATGGTGGGCTGTGGGGTGGCAGTTTTATGTTTGTGGGTTTCCTGCGGCGCTGCAGCGGGA
CAGCTCGAGTACTCAGTGCCGGAGGAGACGGAGCGGGGCGTAGCCGTAGGCAATCTCTCC
GCGGACTTGAGGCTGCCAGCGGCCGCTATGTCCTCGCGGAACTTTCGCTTCCTTTCCAGC
CACCGCGAGCTCTACTTCGGGGTGGATCTACCCAGCGGCAATTTGGTGGTCAGAGAGCCG
GCGGACCGCGAACAGCTGTGCAGGGCCAAAGCTGCCTGCGTCTTGACCTACGACCTGGTG
CTCGAGGACCCGCTGGAGCTGCACAAGATTCGGATTCACGTCCTGGACACCAATGACAAC
TCACCTCTCTTTCCTGCCGGCGACGTGCAGCTGCACATCCCCGAGTTCCTGACGCCCGGA
GCCCGCTTTACTCTCCCGAATGCCCAAGATGACGACGAGGGAAGCAATGGGATACTAAGC
TACAGCCTAAGCCCCAGTCAGCACTTTCGCCTGGACATGGGATCGCGGGTTGACGGCAGC
GAATACCCGGAGTTGGTGTTGGAGAAAGCACTGGATCGCGAACAGCGCGCCACCCACCTG
CTGGTGCTTACAGCTCGGGACGGCGGGCTACCTGCCCGCTCAGGAGACGCACAAGTCACC
ATCATTGTGGTGGACACAAATGACAACGCGCCTGTATTTGAGCGCTCCGTATACCGCACC
AAGGTTCCAGAGACTGCACCCAATGGGACTGTGTTATTCCGAGTTCAAGCCTTGGATCCA
GATGAAGGGTCCAATGGGGAAGTCCAATACTCCCTAAGCAACAGCACGCAAGCAGAGCTG
CGACACCGCTTTCACGTGCACCCTAAAAGTGGGGAGGTGCAAGTAGCTGCTTCACTAGGT
CCGCCTGAAACGCTCTTGGAGGCATACATTGAGGCGAGGGACGAAGGTGTCTTTGGTTTA
GCTAGCACCGCTAAACTGCTGGTGGAGGTGACTGACGTGAACGATCATGCCCCCGAACTG
GACTTCCTGACTCTTTCGAACCCAGTACCTGAGGACGCTGCCCCTGGCACAGTGATTGCT
CTCTTTAGTGTAAAGGATGAAGACCTCGATTCTAATGGTAGGGTCATTTGTGGCATGTCT
AGTGCAGGCCCTTTTCAGCTGACGGCTTCCTTTGACAACTACTACAGCCTGCTGATTGAT
GGGCCCCTGGACCGGGAGCAGATCAGTGAATACCAAGTCCTGATCACGGCCTCAGATAGT
GGCTCACCGCCACTTAGCACCCGAAGGACAATCACTGTGTCAGTTGCTGATGTGAATGAC
AATACACCAAACTTTCCTCAACCCCAGCAGGAACTTTTCGTTGCTGAAAACAATGGCCCT
GGGGCCTCTCTAGGCCGAGTGTTTGCCCAGGACCCCGACCTGGGGAAGAATGGCCTTGTC
TCTTATGAGCTGTTGGATGTTATCTCTGAAGGGCCATCAGCCTCTAGCTTGGTGGCAGTG
GAATCATCCAGTGGGGCCATCACTGCCAAAACTTCCTTTGACTTTGAGCAGCTCAGGGGG
TTTCATTTCCAAGTAGAAGGCCGGGATGGTGGCATTCCTCCCAGAAGTGCAACAGTGACT
ATAAACTTGTTTGTGGTAGATAGGAATGACAATTATCCGGTTATCTTGTTTCCCTTGCCC
AGAAATGGTTCTGTCCCAGTGGAAATTGTGCCCCGCTCTGCCAGGACTGGACACTTGGTC
ACAAAAGTGGTAGCAGAGGATGCTGACAGTGGTTCTAATGCCTGGCTTTCCTACCACATC
TCCCGGGCGTCTGACTCTAGTCTCTTTAGAATTTCAGCCAATATAGGTGAGCTCCGTACT
GCTCGCTTAGTTCTTCCCACTGATGCAGTTAAGCAGAGGGTGGTGGTAGTGGTTCGGGAC
CATGGAGACCCACCACTTTCCTCCTCTGTCACTCTGGGTGTGCTGTTGAGCAACTCTGTC
CCTCAGTTACTTCCAGACTTTGAAGATGTCTGGGAACCAGGAGGGCAGCTTTCTGCCCAG
AACTTGTATTTAGTAATTGCCTTGGCTTGTATTTCCTTTTTATTTCTGGGGTGCTTACTT
TTCTTCGTGTGTACCAAGTTGCACCAGAGCCCAGGCTGTTGCGCTCAGAGCTGCTGTCGC
TCTACAGAGGATCTGAGGTATGGAAGTAAGATGGTTTCAAATCCTTGCATGACATCAGCC
ACCATAGATGTCACTACAGTTGAGAGACTTTCTCAGACTTATCTCTATCGGGCCTCTCTG
GGACTTGGTTCTGATAATAACAGTTTGCTGTTGCGTGGGGAGTACAATGCTGCCGACCTG
CGAAATCTTGCCACTGGGGTAGGACTGAATTTGCCAATATCCTGTATTCAGATTCGGAAT
AGGAAAGGGGATCACGCTAATGTCAATGCCATGCCACGACAGCCCAACCCTGACTGGCGT
TACTCTGCCTCCCTGAGAGCAGGCATGCACAGCTCTGTGCACCTAGAGGAGGCTGGCATT
CTACGGGCTGGTCCAGGAGGGCCTGATCAGCAGTGGCCAACAGTATCCAGTGCAACACCA
GAACCAGAGGCAGGAGAAGTGTCCCCTCCAGTCGGTGCGGGTGTCAACAGCAACAGCTGG
ACCTTTAAATACGGACCAGGCAACCCCAAACAATCCGGTCCCGGTGAGTTGCCCGACAAA
TTCATTATCCCAGGATCTCCTGCAATCATCTCCATCCGGCAGGAGCCTACTAACAGCCAA
ATTGACAAAAGTGACTTCATAACCTTCGGCAAAAAGGAGGAGACCAAGAAAAAGAAGAAA
AAGAAGAAGGGTAACAAGACCCAGGAGAAAAAAGAGAAAGGGAACAGCACGACTGACAAC
AGTGACCAGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 963 |
| Molecular Weight
| 103940.7 |
| Theoretical pI
| 4.83 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Protocadherin alpha-C1
MVGCGVAVLCLWVSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSS
HRELYFGVDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDN
SPLFPAGDVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGS
EYPELVLEKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRT
KVPETAPNGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLG
PPETLLEAYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIA
LFSVKDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDS
GSPPLSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLV
SYELLDVISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVT
INLFVVDRNDNYPVILFPLPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHI
SRASDSSLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSV
PQLLPDFEDVWEPGGQLSAQNLYLVIALACISFLFLGCLLFFVCTKLHQSPGCCAQSCCR
STEDLRYGSKMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLLLRGEYNAADL
RNLATGVGLNLPISCIQIRNRKGDHANVNAMPRQPNPDWRYSASLRAGMHSSVHLEEAGI
LRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDK
FIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDN
SDQ
|
| External Links |
|---|
| GenBank ID Protein
| 5456892 |
| UniProtKB/Swiss-Prot ID
| Q9H158 |
| UniProtKB/Swiss-Prot Entry Name
| PCDC1_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF152303 |
| GeneCard ID
| PCDHAC1 |
| GenAtlas ID
| PCDHAC1 |
| HGNC ID
| HGNC:8676 |
| References |
|---|
| General References
| Not Available |