Identification
HMDB Protein ID CDBP03122
Secondary Accession Numbers Not Available
Name Protocadherin alpha-C1
Description Not Available
Synonyms
  1. PCDH-alpha-C1
Gene Name PCDHAC1
Protein Type Metal Binding
Biological Properties
General Function Involved in calcium ion binding
Specific Function Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain
GO Classification
Component
membrane
cell part
plasma membrane
Function
ion binding
cation binding
metal ion binding
binding
calcium ion binding
Process
homophilic cell adhesion
cell adhesion
cellular process
cell-cell adhesion
Cellular Location
  1. Cell membrane
  2. Single-pass type I membrane protein
Pathways
Gene Properties
Chromosome Location Chromosome:5
Locus 5q31
SNPs PCDHAC1
Gene Sequence
>2892 bp
ATGGTGGGCTGTGGGGTGGCAGTTTTATGTTTGTGGGTTTCCTGCGGCGCTGCAGCGGGA
CAGCTCGAGTACTCAGTGCCGGAGGAGACGGAGCGGGGCGTAGCCGTAGGCAATCTCTCC
GCGGACTTGAGGCTGCCAGCGGCCGCTATGTCCTCGCGGAACTTTCGCTTCCTTTCCAGC
CACCGCGAGCTCTACTTCGGGGTGGATCTACCCAGCGGCAATTTGGTGGTCAGAGAGCCG
GCGGACCGCGAACAGCTGTGCAGGGCCAAAGCTGCCTGCGTCTTGACCTACGACCTGGTG
CTCGAGGACCCGCTGGAGCTGCACAAGATTCGGATTCACGTCCTGGACACCAATGACAAC
TCACCTCTCTTTCCTGCCGGCGACGTGCAGCTGCACATCCCCGAGTTCCTGACGCCCGGA
GCCCGCTTTACTCTCCCGAATGCCCAAGATGACGACGAGGGAAGCAATGGGATACTAAGC
TACAGCCTAAGCCCCAGTCAGCACTTTCGCCTGGACATGGGATCGCGGGTTGACGGCAGC
GAATACCCGGAGTTGGTGTTGGAGAAAGCACTGGATCGCGAACAGCGCGCCACCCACCTG
CTGGTGCTTACAGCTCGGGACGGCGGGCTACCTGCCCGCTCAGGAGACGCACAAGTCACC
ATCATTGTGGTGGACACAAATGACAACGCGCCTGTATTTGAGCGCTCCGTATACCGCACC
AAGGTTCCAGAGACTGCACCCAATGGGACTGTGTTATTCCGAGTTCAAGCCTTGGATCCA
GATGAAGGGTCCAATGGGGAAGTCCAATACTCCCTAAGCAACAGCACGCAAGCAGAGCTG
CGACACCGCTTTCACGTGCACCCTAAAAGTGGGGAGGTGCAAGTAGCTGCTTCACTAGGT
CCGCCTGAAACGCTCTTGGAGGCATACATTGAGGCGAGGGACGAAGGTGTCTTTGGTTTA
GCTAGCACCGCTAAACTGCTGGTGGAGGTGACTGACGTGAACGATCATGCCCCCGAACTG
GACTTCCTGACTCTTTCGAACCCAGTACCTGAGGACGCTGCCCCTGGCACAGTGATTGCT
CTCTTTAGTGTAAAGGATGAAGACCTCGATTCTAATGGTAGGGTCATTTGTGGCATGTCT
AGTGCAGGCCCTTTTCAGCTGACGGCTTCCTTTGACAACTACTACAGCCTGCTGATTGAT
GGGCCCCTGGACCGGGAGCAGATCAGTGAATACCAAGTCCTGATCACGGCCTCAGATAGT
GGCTCACCGCCACTTAGCACCCGAAGGACAATCACTGTGTCAGTTGCTGATGTGAATGAC
AATACACCAAACTTTCCTCAACCCCAGCAGGAACTTTTCGTTGCTGAAAACAATGGCCCT
GGGGCCTCTCTAGGCCGAGTGTTTGCCCAGGACCCCGACCTGGGGAAGAATGGCCTTGTC
TCTTATGAGCTGTTGGATGTTATCTCTGAAGGGCCATCAGCCTCTAGCTTGGTGGCAGTG
GAATCATCCAGTGGGGCCATCACTGCCAAAACTTCCTTTGACTTTGAGCAGCTCAGGGGG
TTTCATTTCCAAGTAGAAGGCCGGGATGGTGGCATTCCTCCCAGAAGTGCAACAGTGACT
ATAAACTTGTTTGTGGTAGATAGGAATGACAATTATCCGGTTATCTTGTTTCCCTTGCCC
AGAAATGGTTCTGTCCCAGTGGAAATTGTGCCCCGCTCTGCCAGGACTGGACACTTGGTC
ACAAAAGTGGTAGCAGAGGATGCTGACAGTGGTTCTAATGCCTGGCTTTCCTACCACATC
TCCCGGGCGTCTGACTCTAGTCTCTTTAGAATTTCAGCCAATATAGGTGAGCTCCGTACT
GCTCGCTTAGTTCTTCCCACTGATGCAGTTAAGCAGAGGGTGGTGGTAGTGGTTCGGGAC
CATGGAGACCCACCACTTTCCTCCTCTGTCACTCTGGGTGTGCTGTTGAGCAACTCTGTC
CCTCAGTTACTTCCAGACTTTGAAGATGTCTGGGAACCAGGAGGGCAGCTTTCTGCCCAG
AACTTGTATTTAGTAATTGCCTTGGCTTGTATTTCCTTTTTATTTCTGGGGTGCTTACTT
TTCTTCGTGTGTACCAAGTTGCACCAGAGCCCAGGCTGTTGCGCTCAGAGCTGCTGTCGC
TCTACAGAGGATCTGAGGTATGGAAGTAAGATGGTTTCAAATCCTTGCATGACATCAGCC
ACCATAGATGTCACTACAGTTGAGAGACTTTCTCAGACTTATCTCTATCGGGCCTCTCTG
GGACTTGGTTCTGATAATAACAGTTTGCTGTTGCGTGGGGAGTACAATGCTGCCGACCTG
CGAAATCTTGCCACTGGGGTAGGACTGAATTTGCCAATATCCTGTATTCAGATTCGGAAT
AGGAAAGGGGATCACGCTAATGTCAATGCCATGCCACGACAGCCCAACCCTGACTGGCGT
TACTCTGCCTCCCTGAGAGCAGGCATGCACAGCTCTGTGCACCTAGAGGAGGCTGGCATT
CTACGGGCTGGTCCAGGAGGGCCTGATCAGCAGTGGCCAACAGTATCCAGTGCAACACCA
GAACCAGAGGCAGGAGAAGTGTCCCCTCCAGTCGGTGCGGGTGTCAACAGCAACAGCTGG
ACCTTTAAATACGGACCAGGCAACCCCAAACAATCCGGTCCCGGTGAGTTGCCCGACAAA
TTCATTATCCCAGGATCTCCTGCAATCATCTCCATCCGGCAGGAGCCTACTAACAGCCAA
ATTGACAAAAGTGACTTCATAACCTTCGGCAAAAAGGAGGAGACCAAGAAAAAGAAGAAA
AAGAAGAAGGGTAACAAGACCCAGGAGAAAAAAGAGAAAGGGAACAGCACGACTGACAAC
AGTGACCAGTGA
Protein Properties
Number of Residues 963
Molecular Weight 103940.7
Theoretical pI 4.83
Pfam Domain Function
Signals
  • ["1-18"]
Transmembrane Regions
  • ["684-704"]
Protein Sequence
>Protocadherin alpha-C1
MVGCGVAVLCLWVSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSS
HRELYFGVDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDN
SPLFPAGDVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGS
EYPELVLEKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRT
KVPETAPNGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLG
PPETLLEAYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIA
LFSVKDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDS
GSPPLSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLV
SYELLDVISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVT
INLFVVDRNDNYPVILFPLPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHI
SRASDSSLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSV
PQLLPDFEDVWEPGGQLSAQNLYLVIALACISFLFLGCLLFFVCTKLHQSPGCCAQSCCR
STEDLRYGSKMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLLLRGEYNAADL
RNLATGVGLNLPISCIQIRNRKGDHANVNAMPRQPNPDWRYSASLRAGMHSSVHLEEAGI
LRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDK
FIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDN
SDQ
GenBank ID Protein 5456892
UniProtKB/Swiss-Prot ID Q9H158
UniProtKB/Swiss-Prot Entry Name PCDC1_HUMAN
PDB IDs Not Available
GenBank Gene ID AF152303
GeneCard ID PCDHAC1
GenAtlas ID PCDHAC1
HGNC ID HGNC:8676
References
General References Not Available