Identification
HMDB Protein ID CDBP03121
Secondary Accession Numbers Not Available
Name Putative protocadherin beta-18
Description Not Available
Synonyms
  1. PCDH-beta-18
  2. PCDH-psi2
Gene Name PCDHB18
Protein Type Metal Binding
Biological Properties
General Function Involved in calcium ion binding
Specific Function Potential calcium-dependent cell-adhesion protein
GO Classification
Component
membrane
cell part
plasma membrane
Function
ion binding
cation binding
metal ion binding
binding
calcium ion binding
Process
cell adhesion
cellular process
cell-cell adhesion
homophilic cell adhesion
Cellular Location
  1. Cell membrane
  2. Single-pass membrane protein (Potential)
Pathways
Gene Properties
Chromosome Location Chromosome:5
Locus 5q31
SNPs PCDHB18
Gene Sequence
>2205 bp
ATGTGGAAGACCTGGCTGCAAGGGGGGGCCAGAGTCATCTTTGACGACTATAAACCTTAT
TTGCGATTGGATCCACAGAATGGCGACTTGCTCTTAAACGAGCAGCTGGACCGGGAGGCA
CTTTGTGATCTCACAGAGCCATGTATATTGCATTTCCAGGTGTTATTTGAAAATCCGTTG
CAATTTTTTCGTGCTGAGCTTTTGGTCAAAGACATAAATGATCACACTCCCACGTTCCTA
AACAATCATATGCTTCTAAAAATCTCCGAAGGTGCTACTCTAGGAACCTTATTCCAAATA
GATAGTGCGCAGGACTTGGATGTGGGAAAGAATGGTGTTCAAAACTATACAATAAGTCCC
AATCCCCATTTCCACCTTAAATTACGGGATAGCGATGAGGGCAGAAAATATCCAGAGTTG
GTACTGGACCAATCCCTGGATCGAGAAAAGGTGTCTGAGTTTAGTTTAACGCTAACAGCC
GTGGATGGCGGGTCTCCGCCCAGGTCTGGGACTACACTGATTAACGTTGTGGTCCTGGAC
ATCAGTGACAATGCCCCTGAATTTGAGAAGCCAGTCTATGAAGTTCATGTACCTGAGAGC
AGCCCTCTGGACTCCTTGATCATCAAAGCGTCTGCTACAGATTTAGATGCAGGAATAAAT
GGAGAACTGTCTTATTCATTTTCCCACGTCTCCAGAGATGTACGGAAAACATTTGAAATC
CATCCAATTTCTGGCGAAGTCTATTTAAAAGCCCCTCTAGATTTCGAGATTATTCAATCT
TATATCATAAATATTCAGGCCATTGAAGGTGGGAGCCTTTCTGGAAAATCAAGCATTTTA
GTTCGGGTTGTAGATGTGAATGACAACCCGCCAGAAATAGCCATGACATCTCTTACCAGC
CCCATACCGGAAAACTCTTCACCTGAGATGGTGGTCGCTGTTTTCAGCATACGAGACCAA
GACGCTGGAGACAATGGGAGAACAGTTTGCTCAATTCAGGACAACCTCCCCTTTGTCTTG
AAGCCTACCTTCAAGAATTTTTACGCTCTGGTAACAGAGCACCCACTGGACAGAGAGGTC
AGAAATGAATATAACATCACCATCACCGTGACCGACTTGGGGACACCCAGGCTGAAAACC
GAGCACAACATAACCGTGCTGGTCTCCGACGTCAATGACAACGCCCCCATCTTCACCCAA
ACCTCCTACACCCTGTTCGTCCGCGAGAACAACAGCCCCGCCCTGCACATCGGCAGCGTC
AGCGCTACAGACAGAGACTCAGGCACCAACGCCCAGGTCACCTACTCGCTGCTGCCGCCC
CAGGACCCGCACCTGCCCCTCACCTCCCTGGTCTCCATCAACGCGGACAACGGCCACCTA
TTCGCCCTCAGGTCTTTGGACTACGAGGCCCTGCAGGAGTTCGGGTTTCGCGTGGGCGCC
GCAGACCACGGCTCCCCGGCGCTGAGCAGCGAGGTGCTGGTGCGCGTGCTGGTGCTGGAC
GCCAACGACAACTCGCCCTTCGTGCTGTACCCGCTGCAGAACGGCTCGGCGCCCTGCACC
GAGCTGGTACCTCGGGCGGCCGAGCCGGGCTACCTGGTGACCAAGGTGGTGGCGGTGGAC
GGCGACTCGGGCCAGAACGCCTGGCTGTCGTACCAGCTGCTCAAGGCCACGGAGCCCGGG
CTGTTCGGCGTGTGGGCGCACAATGGCGAGGGGCGCACCGCCAGGCTGCTGAGCGAGCGC
GACGCGGCCAAGCACAGGCTGGTGGTGCTGGTCAAGGACAATGGCGAGCCTCCGCGCTCG
GCCACCGCCACGCTGCACGTGCTCCTGGTGGAGGGCTTCTCTCAGCCCTACCTGCCTCTC
ACGGAGGCTGCCCCCTCCCAGGCCCAGGCCGACTCCCTCACCGTCTACCTGGTGGTGGCG
TTGGCCTCGGTGTCGTCGCTCTTCCTCTTCTCGGTGTTCCTGTTCGTGGCGGTGCGGCTG
TGCAGGAGGAGCAGGGCGGCCTCGATGGGTCGCTGCTCGGTGCCCGAGTGTCCCTTTCCA
GGGCATCTGGTAGACGTGAGCGGCACCGGGACCCTATCCCAGAGCTACCAGTACGAGGTG
TGTCTGACGGGAGGCTCAGGGGCAAATGAGTTCAAGTTCCTGAAGCCGGTGATTCCCAAT
CTCCTGTCCCGCGACAGCGAAATGGAGAAAGCCCCACCTTTCTGA
Protein Properties
Number of Residues 734
Molecular Weight 80472.1
Theoretical pI 4.64
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["638-658"]
Protein Sequence
>Putative protocadherin beta-18
MWKTWLQGGARVIFDDYKPYLRLDPQNGDLLLNEQLDREALCDLTEPCILHFQVLFENPL
QFFRAELLVKDINDHTPTFLNNHMLLKISEGATLGTLFQIDSAQDLDVGKNGVQNYTISP
NPHFHLKLRDSDEGRKYPELVLDQSLDREKVSEFSLTLTAVDGGSPPRSGTTLINVVVLD
ISDNAPEFEKPVYEVHVPESSPLDSLIIKASATDLDAGINGELSYSFSHVSRDVRKTFEI
HPISGEVYLKAPLDFEIIQSYIINIQAIEGGSLSGKSSILVRVVDVNDNPPEIAMTSLTS
PIPENSSPEMVVAVFSIRDQDAGDNGRTVCSIQDNLPFVLKPTFKNFYALVTEHPLDREV
RNEYNITITVTDLGTPRLKTEHNITVLVSDVNDNAPIFTQTSYTLFVRENNSPALHIGSV
SATDRDSGTNAQVTYSLLPPQDPHLPLTSLVSINADNGHLFALRSLDYEALQEFGFRVGA
ADHGSPALSSEVLVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVD
GDSGQNAWLSYQLLKATEPGLFGVWAHNGEGRTARLLSERDAAKHRLVVLVKDNGEPPRS
ATATLHVLLVEGFSQPYLPLTEAAPSQAQADSLTVYLVVALASVSSLFLFSVFLFVAVRL
CRRSRAASMGRCSVPECPFPGHLVDVSGTGTLSQSYQYEVCLTGGSGANEFKFLKPVIPN
LLSRDSEMEKAPPF
GenBank ID Protein 14009451
UniProtKB/Swiss-Prot ID Q96TA0
UniProtKB/Swiss-Prot Entry Name PCDBI_HUMAN
PDB IDs Not Available
GenBank Gene ID AF217743
GeneCard ID PCDHB18
GenAtlas ID PCDHB18
HGNC ID HGNC:14548
References
General References Not Available