| Identification |
|---|
| HMDB Protein ID
| CDBP03120 |
| Secondary Accession Numbers
| Not Available |
| Name
| Protocadherin beta-16 |
| Description
| Not Available |
| Synonyms
|
- PCDH-beta-16
- Protocadherin-3X
|
| Gene Name
| PCDHB16 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain |
| GO Classification
|
| Component |
| membrane |
| cell part |
| plasma membrane |
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| calcium ion binding |
| Process |
| cell adhesion |
| cellular process |
| cell-cell adhesion |
| homophilic cell adhesion |
|
| Cellular Location
|
- Membrane
- Single-pass type I membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:5 |
| Locus
| 5q31 |
| SNPs
| PCDHB16 |
| Gene Sequence
|
>2331 bp
ATGGAGATTGGATGGATGCACAATCGGAGACAAAGGCAAGTCCTTGTTTTCTTTGTTTTG
CTGAGCTTGTCTGGGGCGGGCGCCGAGTTGGGGTCCTATTCCGTAGTGGAAGAAACGGAG
AGAGGCTCTTTTGTGGCAAATCTAGGAAAAGACCTGGGGTTGGGGTTGACAGAGATGTCC
ACCCGCAAGGCCAGGATCATTTCCCAGGGGAACAAACAGCATTTGCAGCTCAAGGCTCAA
ACTGGGGATTTGCTCATAAATGAGAAGCTAGATCGAGAGGAGCTATGCGGTCCCACTGAG
CCTTGCATACTACATTTCCAAGTGTTAATGGAAAACCCTTTAGAAATATTTCAGGCTGAA
CTGAGGGTGATAGATATAAATGACCATTCTCCCATGTTCACTGAAAAGGAAATGATTCTA
AAAATACCGGAAAACAGTCCTCTAGGAACTGAGTTCCCTCTGAATCATGCTTTGGACTTG
GACGTAGGAAGCAATAATGTTCAAAACTATAAAATCAGCCCAAGCTCTCATTTCCGGGTT
CTAATCCATGAATTCAGAGATGGCAGGAAATACCCTGAGCTAGTGTTGGATAAAGAGCTG
GATCGGGAGGAGGAGCCTCAACTAAGATTAACCCTGACAGCGCTGGATGGTGGCTCTCCA
CCGCGATCTGGAACTGCTCAGGTCCGTATTGAAGTGGTGGACATCAATGATAACGCTCCT
GAGTTTGAGCAGCCCATCTACAAAGTGCAGATTCCAGAGAACAGTCCTCTTGGCTCCCTG
GTTGCCACCGTCTCCGCCAGGGATTTAGACGGCGGAGCCAATGGAAAAATATCATACACA
CTCTTTCAGCCTTCGGAGGATATTAGTAAAACTTTGGAGGTAAATCCTATGACAGGGGAA
GTTCGACTGAGAAAGCAAGTAGATTTCGAAATGGTTACGTCTTATGAAGTGCGCATCAAA
GCCACAGATGGGGGAGGTCTTTCAGGAAAGTGCACTCTTCTCCTGCAGGTGGTGGACGTG
AATGACAATCCCCCACAGGTGACCATGTCTGCACTCACCAGCCCCATCCCAGAGAACTCG
CCTGAGATAGTAGTTGCTGTTTTCAGCGTTTCAGATCCTGACTCCGGAAACAATGGGAAG
ACGATTTCCTCCATCCAGGAAGACCTTCCCTTTCTTCTAAAACCTTCAGTCAAGAACTTT
TACACCTTGGTAACGGAGAGAGCACTCGACAGAGAAGCAAGAGCTGAATATAATATCACC
CTCACCGTCACAGATATGGGGACTCCAAGGCTGAAAACGGAGCACAACATAACAGTGCAG
ATATCAGATGTCAATGATAACGCCCCCACTTTCACCCAAACCTCCTACACCCTGTTCGTC
CGCGAGAACAACAGCCCCGCCCTGCACATCGGCAGCGTCAGCGCCACAGACAGAGACTCA
GGCACCAACGCCCAGGTCACCTACTCGCTGCTGCCGCCCCAGGACCCGCACCTGCCCCTC
GCCTCCCTGGTCTCCATCAACGCAGACAACGGCCACCTGTTCGCCCTCAGGTCGCTGGAC
TACGAGGCCCTGCGGGAGTTCGAGTTCCGCGTGAGCGCCACAGACCGCGGCTCCCCGGCT
TTGAGCAGCGAGGCGCTGGTGCGCGTGCTGGTGCTGGACGCCAACGACAACTCGCCCTTC
GTGCTGTACCCGCTGCAGAACGGCTCCGCGCCCTGCACTGAGCTGGTGCCCCGGGCGGCC
GAGCCGGGCTACCTGGTGACCAAGGTGGTGGCGGTGGACGGCGACTCGGGCCAGAATGCC
TGGCTGTCGTACCAGCTGCTCAAGGCCACGGAGCCCGGGCTGTTCGGTGTGTGGGCGCAC
AATGGCGAGGTGCGCACCGCCAGGCTGCTGAGCGAGCGCGACGCAGCCAAGCAGAGGCTG
GTGGTGCTGGTCAAGGACAATGGCGAGCCTCCGCGCTCGGCCACCGCCACGCTGCACGTG
CTCCTGGTGGACGGCTTCTCCCAGCCCTTCCTGCCGCTCCCAGAGGCGGCCCCCGGCCAG
ACCCAGGCCAACTCGCTCACTGTCTACCTGGTGGTGGCGTTGGCCTCGGTGTCGTCGCTC
TTCCTCTTTTCGGTGCTCCTGTTCGTGGCGGTGCGGCTGTGCAGGAGGAGCAGGGCGGCC
TCGGTGGGCCGCTGCTCGATGCCTGAGGGCCCCTTTCCAGGGCGTCTGGTGGACGTAAGC
GGCACCGGGACCCTGTCCCAGAGCTACCAATACGAGGTGTGTCTGACAGGAGGCTCAGAA
ACAAGTGAGTTCAAGTTCCTGAAGCCGATTATCCCCAACTTCTCTCCTTAG
|
| Protein Properties |
|---|
| Number of Residues
| 776 |
| Molecular Weight
| 84982.5 |
| Theoretical pI
| 4.75 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Protocadherin beta-16
MEIGWMHNRRQRQVLVFFVLLSLSGAGAELGSYSVVEETERGSFVANLGKDLGLGLTEMS
TRKARIISQGNKQHLQLKAQTGDLLINEKLDREELCGPTEPCILHFQVLMENPLEIFQAE
LRVIDINDHSPMFTEKEMILKIPENSPLGTEFPLNHALDLDVGSNNVQNYKISPSSHFRV
LIHEFRDGRKYPELVLDKELDREEEPQLRLTLTALDGGSPPRSGTAQVRIEVVDINDNAP
EFEQPIYKVQIPENSPLGSLVATVSARDLDGGANGKISYTLFQPSEDISKTLEVNPMTGE
VRLRKQVDFEMVTSYEVRIKATDGGGLSGKCTLLLQVVDVNDNPPQVTMSALTSPIPENS
PEIVVAVFSVSDPDSGNNGKTISSIQEDLPFLLKPSVKNFYTLVTERALDREARAEYNIT
LTVTDMGTPRLKTEHNITVQISDVNDNAPTFTQTSYTLFVRENNSPALHIGSVSATDRDS
GTNAQVTYSLLPPQDPHLPLASLVSINADNGHLFALRSLDYEALREFEFRVSATDRGSPA
LSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSGQNA
WLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKQRLVVLVKDNGEPPRSATATLHV
LLVDGFSQPFLPLPEAAPGQTQANSLTVYLVVALASVSSLFLFSVLLFVAVRLCRRSRAA
SVGRCSMPEGPFPGRLVDVSGTGTLSQSYQYEVCLTGGSETSEFKFLKPIIPNFSP
|
| External Links |
|---|
| GenBank ID Protein
| 14195605 |
| UniProtKB/Swiss-Prot ID
| Q9NRJ7 |
| UniProtKB/Swiss-Prot Entry Name
| PCDBG_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_020957.1 |
| GeneCard ID
| PCDHB16 |
| GenAtlas ID
| PCDHB16 |
| HGNC ID
| HGNC:14546 |
| References |
|---|
| General References
| Not Available |