Identification
HMDB Protein ID CDBP03119
Secondary Accession Numbers Not Available
Name Protocadherin beta-15
Description Not Available
Synonyms
  1. PCDH-beta-15
Gene Name PCDHB15
Protein Type Metal Binding
Biological Properties
General Function Involved in calcium ion binding
Specific Function Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain
GO Classification
Component
membrane
cell part
plasma membrane
Function
ion binding
cation binding
metal ion binding
binding
calcium ion binding
Process
homophilic cell adhesion
cell adhesion
cellular process
cell-cell adhesion
Cellular Location
  1. Cell membrane
  2. Single-pass type I membrane protein
Pathways
Gene Properties
Chromosome Location Chromosome:5
Locus 5q31
SNPs PCDHB15
Gene Sequence
>2364 bp
ATGGAGCCTGCAGGGGAGCGCTTTCCCGAACAAAGGCAAGTCCTGATTCTCCTTCTTTTA
CTGGAAGTGACTCTGGCAGGCTGGGAACCCCGTCGCTATTCTGTGATGGAGGAAACAGAG
AGAGGTTCTTTTGTAGCCAACCTGGCCAATGACCTAGGGCTGGGAGTGGGGGAGCTAGCC
GAGCGGGGAGCCCGGGTAGTTTCTGAGGATAACGAACAAGGCTTGCAGCTTGATCTGCAG
ACCGGGCAGTTGATATTAAATGAGAAGCTGGACCGGGAGAAGCTGTGTGGCCCTACTGAG
CCCTGTATAATGCATTTCCAAGTGTTACTGAAAAAACCTTTGGAAGTATTTCGAGCTGAA
CTACTAGTGACAGACATAAACGATCATTCTCCTGAGTTTCCTGAAAGAGAAATGACCCTG
AAAATCCCAGAAACTAGCTCCCTTGGGACTGTGTTTCCTCTGAAAAAAGCTCGGGACTTG
GACGTGGGCAGCAATAATGTTCAAAACTACAATATTTCTCCCAATTCTCATTTCCATGTT
TCCACTCGCACCCGAGGGGATGGCAGGAAATACCCAGAGCTGGTGCTGGACACAGAACTG
GATCGCGAGGAGCAGGCCGAGCTCAGATTAACCTTGACAGCGGTGGACGGTGGCTCTCCA
CCCCGATCTGGCACCGTCCAGATCCTCATCTTGGTCTTGGACGCCAATGACAATGCCCCG
GAGTTTGTGCAGGCGCTCTACGAGGTGCAGGTCCCAGAGAACAGCCCAGTAGGCTCCCTA
GTTGTCAAGGTCTCTGCTAGGGATTTAGACACTGGGACAAATGGAGAGATATCATACTCC
CTTTATTACAGCTCTCAGGAGATAGACAAACCTTTTGAGCTAAGCAGCCTTTCAGGAGAA
ATTCGACTAATTAAAAAACTAGATTTTGAGACAATGTCTTCGTATGATCTAGATATAGAG
GCATCTGATGGCGGGGGACTTTCTGGAAAATGCTCTGTCTCTGTTAAGGTGCTGGATGTT
AACGATAACTTCCCGGAACTAAGTATTTCATCACTTACCAGCCCTATTCCCGAGAATTCT
CCAGAGACAGAAGTGGCCCTGTTTAGGATTAGAGACCGAGACTCTGGGGAAAATGGAAAA
ATGATTTGCTCAATTCAGGATGATGTTCCTTTTAAGCTAAAACCTTCTGTTGAGAATTTC
TACAGGCTGGTAACAGAAGGGGCGCTGGACAGAGAGACCAGAGCCGAGTACAACATCACC
ATCACCATCACAGACTTGGGGACTCCAAGGCTGAAAACCGAGCAGAGCATAACCGTGCTG
GTGTCGGACGTCAATGACAACGCCCCCGCCTTCACCCAAACCTCCTACACCCTGTTCGTC
CGCGAGAACAACAGCCCCGCCCTGCACATCGGCAGTGTCAGCGCCACAGACAGAGACTCG
GGCACCAACGCCCAGGTCACCTACTCGCTGCTGCCGCCCCGGGACCCGCACCTGCCCCTC
ACCTCCCTGGTCTCCATTAACACGGACAACGGCCACCTGTTCGCTCTCCAGTCGCTGGAC
TACGAGGCCCTGCAGGCTTTCGAGTTCCGCGTGGGCGCCACAGACCGCGGCTTCCCGGCG
CTGAGCAGCGAGGCGCTGGTGCGAGTGCTGGTGCTGGACGCCAACGACAACTCGCCCTTC
GTGCTGTACCCGCTGCAGAACGGCTCCGCGCCCTGCACCGAGCTGGTGCCCCGGGCGGCC
GAGCCGGGCTACCTGGTGACCAAGGTGGTGGCGGTGGACGGCGACTCGGGCCAGAACGCC
TGGCTGTCGTACCAGCTGCTCAAGGCCACGGAGCCCGGGCTGTTCGGCGTGTGGGCGCAC
AATGGCGAGGTGCGCACCGCCAGGCTGCTGAGCGAGCGCGACGTGGCCAAGCACAGGCTA
GTGGTGCTGGTCAAGGACAATGGCGAGCCTCCGCGCTCGGCCACCGCCACGCTGCAAGTG
CTCCTGGTGGACGGCTTCTCTCAGCCCTACCTGCCGCTCCCAGAGGCGGCCCCGGCCCAA
GCCCAGGCCGACTCGCTTACCGTCTACCTGGTGGTGGCATTGGCCTCGGTGTCTTCGCTC
TTCCTCTTCTCGGTGTTCCTGTTCGTGGCAGTGCGGCTGTGCAGGAGGAGCAGGGCGGCC
TCAGTGGGTCGCTGCTCGGTGCCCGAGGGCCCCTTTCCAGGGCATCTGGTGGACGTGAGC
GGCACCGGGACCCTTTCCCAGAGCTACCAGTACGAGGTGTGTCTGACGGGAGGCTCTGAA
AGTAATGATTTCAAGTTCTTGAAGCCTATATTCCCAAATATTGTAAGCCAGGACTCTAGG
AGGAAATCAGAATTTCTAGAATAA
Protein Properties
Number of Residues 787
Molecular Weight 86328.4
Theoretical pI 4.46
Pfam Domain Function
Signals
  • ["1-26"]
Transmembrane Regions
  • ["691-711"]
Protein Sequence
>Protocadherin beta-15
MEPAGERFPEQRQVLILLLLLEVTLAGWEPRRYSVMEETERGSFVANLANDLGLGVGELA
ERGARVVSEDNEQGLQLDLQTGQLILNEKLDREKLCGPTEPCIMHFQVLLKKPLEVFRAE
LLVTDINDHSPEFPEREMTLKIPETSSLGTVFPLKKARDLDVGSNNVQNYNISPNSHFHV
STRTRGDGRKYPELVLDTELDREEQAELRLTLTAVDGGSPPRSGTVQILILVLDANDNAP
EFVQALYEVQVPENSPVGSLVVKVSARDLDTGTNGEISYSLYYSSQEIDKPFELSSLSGE
IRLIKKLDFETMSSYDLDIEASDGGGLSGKCSVSVKVLDVNDNFPELSISSLTSPIPENS
PETEVALFRIRDRDSGENGKMICSIQDDVPFKLKPSVENFYRLVTEGALDRETRAEYNIT
ITITDLGTPRLKTEQSITVLVSDVNDNAPAFTQTSYTLFVRENNSPALHIGSVSATDRDS
GTNAQVTYSLLPPRDPHLPLTSLVSINTDNGHLFALQSLDYEALQAFEFRVGATDRGFPA
LSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSGQNA
WLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDVAKHRLVVLVKDNGEPPRSATATLQV
LLVDGFSQPYLPLPEAAPAQAQADSLTVYLVVALASVSSLFLFSVFLFVAVRLCRRSRAA
SVGRCSVPEGPFPGHLVDVSGTGTLSQSYQYEVCLTGGSESNDFKFLKPIFPNIVSQDSR
RKSEFLE
GenBank ID Protein 5457037
UniProtKB/Swiss-Prot ID Q9Y5E8
UniProtKB/Swiss-Prot Entry Name PCDBF_HUMAN
PDB IDs Not Available
GenBank Gene ID AF152494
GeneCard ID PCDHB15
GenAtlas ID PCDHB15
HGNC ID HGNC:8686
References
General References Not Available