| Identification |
|---|
| HMDB Protein ID
| CDBP03119 |
| Secondary Accession Numbers
| Not Available |
| Name
| Protocadherin beta-15 |
| Description
| Not Available |
| Synonyms
|
- PCDH-beta-15
|
| Gene Name
| PCDHB15 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain |
| GO Classification
|
| Component |
| membrane |
| cell part |
| plasma membrane |
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| calcium ion binding |
| Process |
| homophilic cell adhesion |
| cell adhesion |
| cellular process |
| cell-cell adhesion |
|
| Cellular Location
|
- Cell membrane
- Single-pass type I membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:5 |
| Locus
| 5q31 |
| SNPs
| PCDHB15 |
| Gene Sequence
|
>2364 bp
ATGGAGCCTGCAGGGGAGCGCTTTCCCGAACAAAGGCAAGTCCTGATTCTCCTTCTTTTA
CTGGAAGTGACTCTGGCAGGCTGGGAACCCCGTCGCTATTCTGTGATGGAGGAAACAGAG
AGAGGTTCTTTTGTAGCCAACCTGGCCAATGACCTAGGGCTGGGAGTGGGGGAGCTAGCC
GAGCGGGGAGCCCGGGTAGTTTCTGAGGATAACGAACAAGGCTTGCAGCTTGATCTGCAG
ACCGGGCAGTTGATATTAAATGAGAAGCTGGACCGGGAGAAGCTGTGTGGCCCTACTGAG
CCCTGTATAATGCATTTCCAAGTGTTACTGAAAAAACCTTTGGAAGTATTTCGAGCTGAA
CTACTAGTGACAGACATAAACGATCATTCTCCTGAGTTTCCTGAAAGAGAAATGACCCTG
AAAATCCCAGAAACTAGCTCCCTTGGGACTGTGTTTCCTCTGAAAAAAGCTCGGGACTTG
GACGTGGGCAGCAATAATGTTCAAAACTACAATATTTCTCCCAATTCTCATTTCCATGTT
TCCACTCGCACCCGAGGGGATGGCAGGAAATACCCAGAGCTGGTGCTGGACACAGAACTG
GATCGCGAGGAGCAGGCCGAGCTCAGATTAACCTTGACAGCGGTGGACGGTGGCTCTCCA
CCCCGATCTGGCACCGTCCAGATCCTCATCTTGGTCTTGGACGCCAATGACAATGCCCCG
GAGTTTGTGCAGGCGCTCTACGAGGTGCAGGTCCCAGAGAACAGCCCAGTAGGCTCCCTA
GTTGTCAAGGTCTCTGCTAGGGATTTAGACACTGGGACAAATGGAGAGATATCATACTCC
CTTTATTACAGCTCTCAGGAGATAGACAAACCTTTTGAGCTAAGCAGCCTTTCAGGAGAA
ATTCGACTAATTAAAAAACTAGATTTTGAGACAATGTCTTCGTATGATCTAGATATAGAG
GCATCTGATGGCGGGGGACTTTCTGGAAAATGCTCTGTCTCTGTTAAGGTGCTGGATGTT
AACGATAACTTCCCGGAACTAAGTATTTCATCACTTACCAGCCCTATTCCCGAGAATTCT
CCAGAGACAGAAGTGGCCCTGTTTAGGATTAGAGACCGAGACTCTGGGGAAAATGGAAAA
ATGATTTGCTCAATTCAGGATGATGTTCCTTTTAAGCTAAAACCTTCTGTTGAGAATTTC
TACAGGCTGGTAACAGAAGGGGCGCTGGACAGAGAGACCAGAGCCGAGTACAACATCACC
ATCACCATCACAGACTTGGGGACTCCAAGGCTGAAAACCGAGCAGAGCATAACCGTGCTG
GTGTCGGACGTCAATGACAACGCCCCCGCCTTCACCCAAACCTCCTACACCCTGTTCGTC
CGCGAGAACAACAGCCCCGCCCTGCACATCGGCAGTGTCAGCGCCACAGACAGAGACTCG
GGCACCAACGCCCAGGTCACCTACTCGCTGCTGCCGCCCCGGGACCCGCACCTGCCCCTC
ACCTCCCTGGTCTCCATTAACACGGACAACGGCCACCTGTTCGCTCTCCAGTCGCTGGAC
TACGAGGCCCTGCAGGCTTTCGAGTTCCGCGTGGGCGCCACAGACCGCGGCTTCCCGGCG
CTGAGCAGCGAGGCGCTGGTGCGAGTGCTGGTGCTGGACGCCAACGACAACTCGCCCTTC
GTGCTGTACCCGCTGCAGAACGGCTCCGCGCCCTGCACCGAGCTGGTGCCCCGGGCGGCC
GAGCCGGGCTACCTGGTGACCAAGGTGGTGGCGGTGGACGGCGACTCGGGCCAGAACGCC
TGGCTGTCGTACCAGCTGCTCAAGGCCACGGAGCCCGGGCTGTTCGGCGTGTGGGCGCAC
AATGGCGAGGTGCGCACCGCCAGGCTGCTGAGCGAGCGCGACGTGGCCAAGCACAGGCTA
GTGGTGCTGGTCAAGGACAATGGCGAGCCTCCGCGCTCGGCCACCGCCACGCTGCAAGTG
CTCCTGGTGGACGGCTTCTCTCAGCCCTACCTGCCGCTCCCAGAGGCGGCCCCGGCCCAA
GCCCAGGCCGACTCGCTTACCGTCTACCTGGTGGTGGCATTGGCCTCGGTGTCTTCGCTC
TTCCTCTTCTCGGTGTTCCTGTTCGTGGCAGTGCGGCTGTGCAGGAGGAGCAGGGCGGCC
TCAGTGGGTCGCTGCTCGGTGCCCGAGGGCCCCTTTCCAGGGCATCTGGTGGACGTGAGC
GGCACCGGGACCCTTTCCCAGAGCTACCAGTACGAGGTGTGTCTGACGGGAGGCTCTGAA
AGTAATGATTTCAAGTTCTTGAAGCCTATATTCCCAAATATTGTAAGCCAGGACTCTAGG
AGGAAATCAGAATTTCTAGAATAA
|
| Protein Properties |
|---|
| Number of Residues
| 787 |
| Molecular Weight
| 86328.4 |
| Theoretical pI
| 4.46 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Protocadherin beta-15
MEPAGERFPEQRQVLILLLLLEVTLAGWEPRRYSVMEETERGSFVANLANDLGLGVGELA
ERGARVVSEDNEQGLQLDLQTGQLILNEKLDREKLCGPTEPCIMHFQVLLKKPLEVFRAE
LLVTDINDHSPEFPEREMTLKIPETSSLGTVFPLKKARDLDVGSNNVQNYNISPNSHFHV
STRTRGDGRKYPELVLDTELDREEQAELRLTLTAVDGGSPPRSGTVQILILVLDANDNAP
EFVQALYEVQVPENSPVGSLVVKVSARDLDTGTNGEISYSLYYSSQEIDKPFELSSLSGE
IRLIKKLDFETMSSYDLDIEASDGGGLSGKCSVSVKVLDVNDNFPELSISSLTSPIPENS
PETEVALFRIRDRDSGENGKMICSIQDDVPFKLKPSVENFYRLVTEGALDRETRAEYNIT
ITITDLGTPRLKTEQSITVLVSDVNDNAPAFTQTSYTLFVRENNSPALHIGSVSATDRDS
GTNAQVTYSLLPPRDPHLPLTSLVSINTDNGHLFALQSLDYEALQAFEFRVGATDRGFPA
LSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSGQNA
WLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDVAKHRLVVLVKDNGEPPRSATATLQV
LLVDGFSQPYLPLPEAAPAQAQADSLTVYLVVALASVSSLFLFSVFLFVAVRLCRRSRAA
SVGRCSVPEGPFPGHLVDVSGTGTLSQSYQYEVCLTGGSESNDFKFLKPIFPNIVSQDSR
RKSEFLE
|
| External Links |
|---|
| GenBank ID Protein
| 5457037 |
| UniProtKB/Swiss-Prot ID
| Q9Y5E8 |
| UniProtKB/Swiss-Prot Entry Name
| PCDBF_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF152494 |
| GeneCard ID
| PCDHB15 |
| GenAtlas ID
| PCDHB15 |
| HGNC ID
| HGNC:8686 |
| References |
|---|
| General References
| Not Available |