Identification
HMDB Protein ID CDBP03111
Secondary Accession Numbers Not Available
Name Protocadherin beta-7
Description Not Available
Synonyms
  1. PCDH-beta-7
Gene Name PCDHB7
Protein Type Metal Binding
Biological Properties
General Function Involved in calcium ion binding
Specific Function Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain
GO Classification
Component
membrane
cell part
plasma membrane
Function
ion binding
cation binding
metal ion binding
binding
calcium ion binding
Process
cell adhesion
cellular process
cell-cell adhesion
homophilic cell adhesion
Cellular Location
  1. Cell membrane
  2. Single-pass type I membrane protein
Pathways
Gene Properties
Chromosome Location Chromosome:5
Locus 5q31
SNPs PCDHB7
Gene Sequence
>2382 bp
ATGGAGGCCAGAGTGGAGCGTGCTGTGCAGAAAAGGCAAGTCTTATTTCTTTGTGTATTT
CTGGGAATGTCTTGGGCTGGCGCCGAACCGCTTCGGTATTTTGTGGCGGAGGAAACCGAG
AGAGGCACCTTTCTTACCAACTTGGCAAAAGACCTAGGGTTAGGGGTAGGGGAACTGAGA
GCCCGGGGAACTAGAATTGTTTCAGACCAGAACATGCAAATTTTACTGCTCAGTTCGCTT
ACTGGTGATCTACTTCTAAATGAGAAATTGGACCGAGAGGAACTGTGTGGCCCCAGAGAG
CCCTGTGTGCTGCCTTTCCAGTTGTTATTGGAAAAACCTTTTCAGATTTTCCGTGCTGAA
CTATGGGTCAGAGACATCAATGATCACGCTCCAGTATTTCTAGACAGAGAGATTTCCTTG
AAAATATTAGAAAGTACCACTCCAGGGGCGGCATTTCTCCTAGAGAGTGCACAGGATTCA
GATGTTGGAACCAACAGCCTGAGTAACTACACCATCAGCCCCAATGCCTATTTCCATATT
AATGTCCATGATAGCGGGGAGGGGAATATCTATCCCGAATTGGTGCTGAATCAAGTGCTG
GATCGGGAAGAGATACCAGAGTTCAGTTTAACCCTCACCGCTTTAGACGGCGGCTCTCCT
CCAAGATCAGGGACCGCCCTCGTGCGCATTCTGGTTCTAGACGTAAATGACAACGCCCCT
GATTTTGTGCGGTCGCTCTACAAGGTGCAGGTGCCCGAAAATAGCCCCGTTGGTTCCATG
GTTGTCTCCGTGTCAGCCAGAGATTTAGATACCGGAAGTAATGGGGAAATAGCCTATGCA
TTTTCTTACGCCACTGAAAGAATTCTCAAAACGTTTCAAATCAATCCAACATCTGGCAGT
CTTCATCTTAAAGCGCAATTGGACTATGAGGCAATTCAAACTTACACATTAACTATTCAG
GCCAAAGACGGCGGCGGGCTTTCTGGAAAATGCACTGTAGTGGTTGATGTAACAGATATA
AACGATAATCGACCCGAGCTGCTCCTGTCTTCACTTACTAGCCCAATTGCAGAAAACTCA
CCCGAGACAGTCGTGGCTGTTTTTAGGATTAGAGACAGAGATTCCGGGAACAATGGAAAG
ACAGTGTGCTCCATCCAGGACGATGTCCCCTTCATCCTGAAGCCATCTGTCGAAAACTTC
TATACTCTGGTAACAGAGAAACCTTTGGATCGAGAGAGGAACACTGAGTACAACATCACC
ATCACCGTCACCGACTTGGGGACACCCAGGCTGAAAACCGAGCACAACATAACCGTGCTG
GTCTCCGACGTCAATGACAACGCTCCCGCCTTCACCCAAACCTCCTACACCCTGTTTGTC
CGTGAGAACAACAGCCCCGCCCTGCCCATCGGCAGTGTCAGCGCCACAGACAGAGACTCG
GGCACCAACGCCCAGGTCATCTACTCCCTGCTGCCGTCCCAGGACCCGCACCTGCCCCTC
GCCTCCCTGGTCTCCATCAACGCGGACAACGGCCACCTGTTTGCCCTCAGGTCCCTGGAC
TACGAGGCCCTGCAGGCGTTCGAGTTCCGCGTGGGCGCCACAGACCGCGGCTCCCCCGCG
CTGAGCAGCGAGGCGCTGGTGCGCGTGCTGGTGCTGGACGCCAACGACAACTCGCCCTTC
GTGCTGTACCCGCTGCAGAACAGCTCCGCGCCCTGCACCGAGCCGTTGCCCCGGGCGGCC
GAGCCGGGCTACCTGGTGACCAAGGTGGTGGCGGTGGACGGCGACTCGGGCCAGAACGCC
TGGCTGTCGTACCAGCTGCTCAAGGCCACGGAGCCCGGGCTATTCGGCGTGTGGGCGCAC
AATGGCGAGGTGCGTACCGCCAGGCTGCTGAGCGAGCGCGACGCAGCCAAGCAGAGGCTG
GTGGTGCTGGTCAAGGACAATGGCGAGCCTCCGCGCTCGGCCACCGCCACGCTGCACGTG
CTCCTGGTGGACGGCTTCTCCCAGCCCTACCTGCGGCTCCCGGAGGCGGCCCCGGACCAG
GCCAACTCGCTCACCGTCTACCTGGTGGTGGCGTTGGCCTCGGTGTCTTCGCTCTTCCTC
CTCTCGGTGCTCCTGTTCGTGGCGGTGCGGCTGTGCAGGAGGAGCAGGGCGGCCCCGGTG
GGTCGCTGCTCGGTGCCTGAGGGCCCCTTTCCACGACATCTGGTGGACTTGAGCGGCACC
GGGACCCTATCCCAGAGCTACCAGTATGAGGTGTGCCTGACTGGAGGCTCCGGGACAAAT
GAGTTCAAGTTTCTGAAACCAATTATCCCCAACCTGCTACCCCAGAGCACAGGCAGGGAA
GTGGAAGAAAATCGCCCATTTCAGAATAATTTGGGTTTCTGA
Protein Properties
Number of Residues 793
Molecular Weight 86706.2
Theoretical pI 4.64
Pfam Domain Function
Signals
  • ["1-26"]
Transmembrane Regions
  • ["689-709"]
Protein Sequence
>Protocadherin beta-7
MEARVERAVQKRQVLFLCVFLGMSWAGAEPLRYFVAEETERGTFLTNLAKDLGLGVGELR
ARGTRIVSDQNMQILLLSSLTGDLLLNEKLDREELCGPREPCVLPFQLLLEKPFQIFRAE
LWVRDINDHAPVFLDREISLKILESTTPGAAFLLESAQDSDVGTNSLSNYTISPNAYFHI
NVHDSGEGNIYPELVLNQVLDREEIPEFSLTLTALDGGSPPRSGTALVRILVLDVNDNAP
DFVRSLYKVQVPENSPVGSMVVSVSARDLDTGSNGEIAYAFSYATERILKTFQINPTSGS
LHLKAQLDYEAIQTYTLTIQAKDGGGLSGKCTVVVDVTDINDNRPELLLSSLTSPIAENS
PETVVAVFRIRDRDSGNNGKTVCSIQDDVPFILKPSVENFYTLVTEKPLDRERNTEYNIT
ITVTDLGTPRLKTEHNITVLVSDVNDNAPAFTQTSYTLFVRENNSPALPIGSVSATDRDS
GTNAQVIYSLLPSQDPHLPLASLVSINADNGHLFALRSLDYEALQAFEFRVGATDRGSPA
LSSEALVRVLVLDANDNSPFVLYPLQNSSAPCTEPLPRAAEPGYLVTKVVAVDGDSGQNA
WLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKQRLVVLVKDNGEPPRSATATLHV
LLVDGFSQPYLRLPEAAPDQANSLTVYLVVALASVSSLFLLSVLLFVAVRLCRRSRAAPV
GRCSVPEGPFPRHLVDLSGTGTLSQSYQYEVCLTGGSGTNEFKFLKPIIPNLLPQSTGRE
VEENRPFQNNLGF
GenBank ID Protein 5457049
UniProtKB/Swiss-Prot ID Q9Y5E2
UniProtKB/Swiss-Prot Entry Name PCDB7_HUMAN
PDB IDs Not Available
GenBank Gene ID AF152500
GeneCard ID PCDHB7
GenAtlas ID PCDHB7
HGNC ID HGNC:8692
References
General References Not Available