Identification
HMDB Protein ID CDBP03109
Secondary Accession Numbers Not Available
Name Protocadherin beta-5
Description Not Available
Synonyms
  1. PCDH-beta-5
Gene Name PCDHB5
Protein Type Metal Binding
Biological Properties
General Function Involved in calcium ion binding
Specific Function Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain
GO Classification
Component
membrane
cell part
plasma membrane
Function
ion binding
cation binding
metal ion binding
binding
calcium ion binding
Process
cell adhesion
cellular process
cell-cell adhesion
homophilic cell adhesion
Cellular Location
  1. Cell membrane
  2. Single-pass type I membrane protein
Pathways
Gene Properties
Chromosome Location Chromosome:5
Locus 5q31
SNPs PCDHB5
Gene Sequence
>2388 bp
ATGGAGACTGCGCTAGCAAAAACGCCACAGAAAAGGCAAGTTATGTTTCTTGCTATATTG
TTGCTTTTGTGGGAGGCTGGCTCTGAGGCAGTTAGGTATTCCATACCAGAAGAAACAGAA
AGTGGCTATTCTGTGGCCAACCTGGCAAAAGACCTGGGTCTTGGGGTGGGGGAACTGGCC
ACTCGGGGCGCGCGAATGCATTACAAAGGAAACAAAGAGCTCTTGCAGCTTGATATAAAG
ACCGGCAATTTGCTTCTATATGAAAAACTAGACCGGGAGGTGATGTGCGGGGCGACAGAA
CCCTGTATATTGCATTTCCAGCTCTTACTAGAAAATCCAGTGCAGTTTTTTCAAACTGAT
CTGCAGCTCACAGATATAAATGACCATGCCCCAGAGTTCCCAGAGAAGGAAATGCTCCTA
AAAATCCCAGAGAGCACCCAGCCAGGGACTGTGTTTCCCTTAAAAATAGCCCAGGACTTT
GACATAGGTAGCAACACTGTTCAGAACTACACAATCAGCCCAAATTCACACTTTCATGTT
GCTACGCATAATCGCGGAGATGGCAGAAAATACCCAGAGCTGGTGCTGGACAAAGCGCTG
GACCGGGAGGAGCGGCCTGAGCTCAGCTTAACACTCACTGCACTGGACGGTGGGGCTCCG
CCCAGGTCCGGGACCACCACAATTCGCATTGTCGTCTTGGATAATAATGACAACGCCCCC
GAATTTTTACAATCATTCTATGAGGTACAGGTGCCCGAGAACAGCCCCCTTAACTCCTTA
GTTGTCGTTGTCTCCGCTCGAGATTTAGATGCAGGAGCATATGGGAGTGTAGCCTATGCT
CTATTCCAAGGCGATGAAGTTACTCAACCATTTGTAATAGACGAGAAAACAGCAGAAATT
CGCCTGAAAAGGGCATTGGATTTCGAGGCAACTCCATATTATAACGTGGAAATTGTAGCC
ACAGATGGTGGGGGCCTTTCAGGAAAATGCACTGTGGCTATAGAAGTGGTGGATGTGAAT
GACAACGCCCCTGAACTCACCATGTCTACGCTCTCCAGCCCTACCCCAGAAAATGCCCCG
GAAACTGTAGTTGCCGTTTTCAGTGTTTCTGATCCAGACTCCGGGGACAACGGTAGGATG
ATTTGCTCCATCCAGAATGATCTCCCCTTTCTTTTGAAGCCCACATTAAAAAACTTTTAC
ACCCTAGTGACACAGAGAACACTGGACAGAGAGAGCCAAGCCGAGTACAACATCACCATC
ACTGTCACCGACATGGGGACACCCAGGCTGAAAACCGAGCACAACATAACGGTCCTGGTC
TCCGACGTCAATGACAACGCCCCCGCCTTCACCCAAACCTCCTACACCCTGTTCGTCCGA
GAGAACAACAGCCCCGCCCTGCACATCGGCAGTGTCAGCGCCACAGACAGAGACTCAGGC
ACCAACGCCCAGGTCACCTACTCGCTGCTGCCGCCCCAGAACCCACACCTGCGCCTCGCC
TCCCTGGTCTCCATCAACGCGGACAACGGCCACCTGTTTGCCCTCAGGTCGCTGGACTAC
GAGGCCCTGCAGGCGTTCGAGTTCCGCGTGGGAGCCACAGACCGCGGCTCCCCGGCGCTG
AGCAGCGAGGCGCTGGTGCGCGTGCTGGTGCTGGACGCCAACGACAACTCGCCCTTCGTG
CTGTATCCGCTGCAGAACGGCTCGGCGCCTTGCACCGAGCTGGTGCCCCGGGCGGCCGAG
CCGGGCTACCTGGTGACCAAGGTGGTGGCGGTGGACGGCGACTCGGGCCAGAACGCCTGG
CTGTCGTACCAGCTGCTCAAGGCCACGGAGCCCGGGCTGTTCAGCATGTGGGCGCACAAT
GGCGAGGTGCGCACCGCCAGGCTGCTGAGCGAGCGCGACGCGGCCAAGCACAGGCTGGTG
GTGCTGGTCAAGGACAATGGCGAGCCTCCGCGCTCGGCCACCGCCACGCTGCACGTGCTC
CTGGTGGACGGCTTCTCCCAGCCCTACCTGCCGCTGCCGGAGGCGGCCCCGGCCCAGGCC
CAGGCCGACTCGCTCACTGTCTACCTGGTGGTGGCATTGGCCTCGGTGTCGTCGCTCTTC
CTCTTTTCGGTGCTCCTGTTCGTGGCAGTGCGGCTGTGCAGGAGGAGCAGGGCGGCCTCG
GTCGGTCGCTGCTCGGTGCCCGAGGGCCCCTTTCCAGGGCATCTGGTGGACGTGAGCGGC
ACCGGGACCCTATCCCAGAGCTACCACTACGAGGTGTGTTTGACCGGAGACTCAGGGGCC
GGCGAGTTCAAGTTCCTGAAGCCGATTATTCCTAACCTTTTGCCCCAGGGCGCTGGTGAA
GAAATAGGGAAAACTGCTGCCTTCCGGAATAGCTTTGGATTAAATTAG
Protein Properties
Number of Residues 795
Molecular Weight 86421.8
Theoretical pI 4.62
Pfam Domain Function
Signals
  • ["1-30"]
Transmembrane Regions
  • ["690-710"]
Protein Sequence
>Protocadherin beta-5
METALAKTPQKRQVMFLAILLLLWEAGSEAVRYSIPEETESGYSVANLAKDLGLGVGELA
TRGARMHYKGNKELLQLDIKTGNLLLYEKLDREVMCGATEPCILHFQLLLENPVQFFQTD
LQLTDINDHAPEFPEKEMLLKIPESTQPGTVFPLKIAQDFDIGSNTVQNYTISPNSHFHV
ATHNRGDGRKYPELVLDKALDREERPELSLTLTALDGGAPPRSGTTTIRIVVLDNNDNAP
EFLQSFYEVQVPENSPLNSLVVVVSARDLDAGAYGSVAYALFQGDEVTQPFVIDEKTAEI
RLKRALDFEATPYYNVEIVATDGGGLSGKCTVAIEVVDVNDNAPELTMSTLSSPTPENAP
ETVVAVFSVSDPDSGDNGRMICSIQNDLPFLLKPTLKNFYTLVTQRTLDRESQAEYNITI
TVTDMGTPRLKTEHNITVLVSDVNDNAPAFTQTSYTLFVRENNSPALHIGSVSATDRDSG
TNAQVTYSLLPPQNPHLRLASLVSINADNGHLFALRSLDYEALQAFEFRVGATDRGSPAL
SSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSGQNAW
LSYQLLKATEPGLFSMWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSATATLHVL
LVDGFSQPYLPLPEAAPAQAQADSLTVYLVVALASVSSLFLFSVLLFVAVRLCRRSRAAS
VGRCSVPEGPFPGHLVDVSGTGTLSQSYHYEVCLTGDSGAGEFKFLKPIIPNLLPQGAGE
EIGKTAAFRNSFGLN
GenBank ID Protein 33150746
UniProtKB/Swiss-Prot ID Q9Y5E4
UniProtKB/Swiss-Prot Entry Name PCDB5_HUMAN
PDB IDs Not Available
GenBank Gene ID AF134474
GeneCard ID PCDHB5
GenAtlas ID PCDHB5
HGNC ID HGNC:8690
References
General References Not Available