| Identification |
|---|
| HMDB Protein ID
| CDBP03107 |
| Secondary Accession Numbers
| Not Available |
| Name
| Protocadherin beta-3 |
| Description
| Not Available |
| Synonyms
|
- PCDH-beta-3
|
| Gene Name
| PCDHB3 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain |
| GO Classification
|
| Component |
| plasma membrane |
| membrane |
| cell part |
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| calcium ion binding |
| Process |
| cell adhesion |
| cellular process |
| cell-cell adhesion |
| homophilic cell adhesion |
|
| Cellular Location
|
- Cell membrane
- Single-pass type I membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:5 |
| Locus
| 5q31 |
| SNPs
| PCDHB3 |
| Gene Sequence
|
>2391 bp
ATGGAGGCGGGAGGAGAGCGATTTCTTAGACAAAGGCAAGTCTTGCTTCTCTTTGTTTTT
CTGGGAGGGTCTCTGGCTGGGTCCGAGTCAAGACGCTATTCTGTGGCTGAGGAAAAAGAG
AAGGGCTTTTTAATAGCCAACCTAGCAAAGGATCTGGGACTAAGGGTAGAGGAACTGGCC
GCGAGGGGGGCCCAAGTTGTGTCCAAAGGGAACAAACAGCATTTTCAGCTCAGTCATCAG
ACAGGTGATTTGCTCCTGAATGAGAAATTGGACCGGGAGGAGCTATGCGGCCCCACAGAA
CCATGCATACTACATTTTCAGATATTACTGCAAAACCCTTTGCAATTCGTTACAAACGAG
CTCCGTATCATAGATGTAAATGACCATTCTCCGGTATTCTTTGAAAATGAAATGCATCTG
AAAATCCTAGAAAGCACTCTGCCAGGAACAGTAATTCCTTTGGGAAATGCTGAGGACTTG
GATGTGGGAAGAAACAGCCTCCAAAACTACACTATCACTCCGAATTCCCACTTCCACGTA
CTCACTCGCAGTCGTAGGGACGGAAGGAAGTACCCGGAACTAGTACTGGATAAAGCGCTC
GATCGGGAGGAGCAGCCGGAACTCAGCTTAACGCTCACCGCGCTGGACGGCGGCTCTCCC
CCTCGGTCTGGGACAGCCCAGATAAACATCCAGGTCTTAGATATAAACGACAATGCACCA
GAATTTGCACAGCCGCTCTATGAGGTTGCAGTTCTAGAGAATACCCCCGTTAACTCTGTC
ATTGTCACTGTCTCGGCTTCTGACTTAGATACAGGAAGTTTTGGGACAATATCATATGCA
TTTTTTCATGCTTCTGAAGAAATTCGCAAAACTTTTCAGCTAAATCCAATTACTGGTGAT
ATGCAACTGGTCAAATATTTGAATTTTGAAGCGATTAATAGTTATGAAGTCGACATCGAG
GCCAAGGATGGCGGAGGCCTATCCGGAAAGTCTACAGTCATAGTCCAGGTGGTTGATGTC
AACGACAACCCACCGGAACTGACCTTGTCTTCAGTAAACAGCCCTATTCCTGAGAACTCG
GGAGAGACTGTACTGGCTGTTTTCAGTGTTTCTGATCTAGACTCTGGAGACAACGGAAGA
GTGATGTGTTCCATTGAGAACAATCTCCCCTTCTTCCTGAAACCATCTGTAGAGAATTTT
TACACCCTAGTGTCAGAAGGCGCGCTGGACAGAGAGACCAGATCCGAGTACAACATTACC
ATCACTATCACTGACCTGGGGACACCCAGGCTGAAAACCAAGTACAACATAACCGTGCTG
GTCTCCGACGTCAATGACAACGCCCCCGCCTTCACCCAAATCTCCTACACCCTGTTCGTC
CGCGAGAACAACAGCCCCGCCCTGCACATCGGCAGTGTCAGCGCCACAGACAGAGACTCA
GGCACCAACGCCCAGGTAACCTACTCGCTGCTGCCGCCCCAGGACCCGCACCTGCCCCTC
TCTTCCCTGGTCTCCATCAACGCGGACAACGGCCACCTGTTTGCCCTCAGGTCGCTGGAC
TACGAGGCCCTGCAGGCGTTCGAGTTCCGCGTGGGCGCCACAGACCGTGGCTCCCCGGCT
TTGAGCAGCGAGGCGCTGGTGCGCGTGCTGGTGCTGGACGCCAACGACAACTCGCCCTTC
GTGCTGTACCCGCTGCAGAACGGCTCCGCGCCCTGCACCGAGCTGGTGCCCCGGGCGGCT
GAGCCGGGCTACCTGGTGACCAAGGTGGTGGCGGTGGACGGCGACTCGGGCCAGAACGCC
TGGCTGTCGTACCAGCTGCTCAAGGCCACGGAGCCCGGGCTGTTCGGCGTGTGGGCGCAC
AATGGCGAAGTGCGCACCGCCAGGCTGCTGAGCGAGCGCGACGCGGCCAAGCACAGGCTG
GTGGTGCTGGTCAAGGACAATGGCGAGCCTCCGCGCTCGGCCACCGCCACGCTGCATGTG
CTCCTGGTGGACGGCTTCTCCCAGCCCTACCTGCCTCTCCCGGAGGCGGCACCGGCCCAG
GCCCAGGCCGACTTGCTCACCGTCTACCTGGTGGTGGCATTGGCCTCGGTGTCTTCGCTC
TTCCTCTTTTCGGTGCTCCTGTTCGTGGCGGTGCGGCTGTGCAGGAGGAGCAGGGCGGCC
TCGGTGGGTCGCTGCTCGGTGCCCGAGGGCCCCTTTCCAGGGCAGATGGTGGACGTGAGC
GGCACCGGGACCCTGTCCCAGAGCTACCAGTACGAGGTGTGTCTGACTGGAGGCTCCGGG
ACAAATGAGTTCAAGTTCCTGAAGCCAATTATCCCCAACTTCGTTGCTCAGGGTGCAGAG
AGGGTTAGCGAGGCAAATCCCAGTTTCAGGAAGAGCTTTGAATTCAGTTAA
|
| Protein Properties |
|---|
| Number of Residues
| 796 |
| Molecular Weight
| 86772.0 |
| Theoretical pI
| 4.62 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Protocadherin beta-3
MEAGGERFLRQRQVLLLFVFLGGSLAGSESRRYSVAEEKEKGFLIANLAKDLGLRVEELA
ARGAQVVSKGNKQHFQLSHQTGDLLLNEKLDREELCGPTEPCILHFQILLQNPLQFVTNE
LRIIDVNDHSPVFFENEMHLKILESTLPGTVIPLGNAEDLDVGRNSLQNYTITPNSHFHV
LTRSRRDGRKYPELVLDKALDREEQPELSLTLTALDGGSPPRSGTAQINIQVLDINDNAP
EFAQPLYEVAVLENTPVNSVIVTVSASDLDTGSFGTISYAFFHASEEIRKTFQLNPITGD
MQLVKYLNFEAINSYEVDIEAKDGGGLSGKSTVIVQVVDVNDNPPELTLSSVNSPIPENS
GETVLAVFSVSDLDSGDNGRVMCSIENNLPFFLKPSVENFYTLVSEGALDRETRSEYNIT
ITITDLGTPRLKTKYNITVLVSDVNDNAPAFTQISYTLFVRENNSPALHIGSVSATDRDS
GTNAQVTYSLLPPQDPHLPLSSLVSINADNGHLFALRSLDYEALQAFEFRVGATDRGSPA
LSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSGQNA
WLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSATATLHV
LLVDGFSQPYLPLPEAAPAQAQADLLTVYLVVALASVSSLFLFSVLLFVAVRLCRRSRAA
SVGRCSVPEGPFPGQMVDVSGTGTLSQSYQYEVCLTGGSGTNEFKFLKPIIPNFVAQGAE
RVSEANPSFRKSFEFS
|
| External Links |
|---|
| GenBank ID Protein
| 5457041 |
| UniProtKB/Swiss-Prot ID
| Q9Y5E6 |
| UniProtKB/Swiss-Prot Entry Name
| PCDB3_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF152496 |
| GeneCard ID
| PCDHB3 |
| GenAtlas ID
| PCDHB3 |
| HGNC ID
| HGNC:8688 |
| References |
|---|
| General References
| Not Available |