| Identification |
|---|
| HMDB Protein ID
| CDBP03104 |
| Secondary Accession Numbers
| Not Available |
| Name
| Protocadherin alpha-13 |
| Description
| Not Available |
| Synonyms
|
- PCDH-alpha-13
|
| Gene Name
| PCDHA13 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain |
| GO Classification
|
| Component |
| membrane |
| cell part |
| plasma membrane |
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| calcium ion binding |
| Process |
| homophilic cell adhesion |
| cell adhesion |
| cellular process |
| cell-cell adhesion |
|
| Cellular Location
|
- Cell membrane
- Single-pass type I membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:5 |
| Locus
| 5q31 |
| SNPs
| PCDHA13 |
| Gene Sequence
|
>2853 bp
ATGCTGTCTTCCTGGCAAGGAGGCCCAAGACCGCGGCAACTACTGCTCTGGCTTCTGATC
CTCGCAGCCTGGGAGACGGGTAGTGGCCAGCTCCACTACTCCGTCCCCGAGGAAGCAAAA
CACGGCACCTTCGTGGGCCGCATCGCTCAGGACCTGGGGCTGGAGCTGGCGGAGCTGGTG
CCGCGCCTGTTCCGGGTGGCGTCCAAAAGACACGGGGACCTTCTGGAGGTAAATCTGCAG
AATGGCATTTTGTTTGTGAATTCTCGGATCGACCGCGAGGAGCTGTGTGGGCGGAGCGCG
GAGTGCAGCATCCACCTGGAGGTGATCGTGGACAGGCCTCTGCAGGTTTTCCATGTGGAG
GTGAAGGTGAGGGACATTAACGACAACCCGCCCATATTCCCTGAAAGCAAGAAACGAATA
ATCATTGCAGAATCTAGACCTCCGGAAACTCGATTTCCACTAGATGGCGCATCCGATGCA
GATATTGGAGTAAACTCGGCATTGACCTACCGACTGGATCCCAACGATTATTTCACTTTG
GACGCACAAAACAGTCTTGAGCAAATGTCTTCATTATCACTTGTACTGAGGAAAACACTG
GACAGAGAGGAAATTCAGGAACATAGTTTATTACTGACAGCCAGTGATGGAGGTAAACCC
GAGCTGACTGGCACAGTTCAGCTGCTCATCACGATTCTGGACGTGAATGACAACGCCCCG
GAATTTTACCAATCCGTTTATAAAGTGACGGTGTTAGAGAACGCCTTCAATGGAACATTA
GTGATCAAGCTAAATGCCACAGATCCTGATGATGGTACAAATGGAGATATAGTTTACTCA
TTTAGAAGGCCTGTATGGCCTGCAGTGGTATATGCATTTACCATAAATCCGAACAATGGA
GAAATTAGGACAAAAGGCAAACTAGATTTCGAAGAAAAGAAATTATATGAAATATCCGTG
GAGGCAGTTGACAAAGGAAATATTCCAATGGCGGGTCATTGTACCCTTTTGGTGGAAGTA
CTAGATGTAAATGATAACGCCCCAGAGGTTACCATCACTTCTTTGTCACTCCCCATCAGA
GAAGACACTCAGCCTAGCGCCATTATTGCCCTAATCAGTGTGTCCGATCGTGACTCTGGC
TCAAATGGACAGGTCACCTGCACCTTGACGCCGCATGTCCCCTTCAAGCTGGTGTCCACC
TACAAGAACTACTACTCATTAGTGCTGGACAGCGCCCTGGACCGCGAGAGCGTATCAGCC
TATGAACTGGTGGTGACCGCGCGGGACGGGGGCTCGCCTTCGCTGTGGGCCACGGCCAGC
GTGTCGGTGGGGGTGGCCGACGTGAACGACAACGCGCCGGCGTTCGCGCAGCCCGAGTAC
ACGGTGTTCGTGAAGGAAAACAATCCGCCGGGCTGCCACATCTTCACGGTGTCTGCTCAG
GACGCGGACGCACAGGAGAACGCGCTGGTCTCCTACTCGCTGGTGGAGCGGCGGGTGGGC
GAGCGTGCGCTGTCGAGCTACGTGTCGGTGCACGCGGAGAGCGGCAAGGTGTACGCGCTG
CAGCCGTTGGACCACGAGGAGCTGGAGCTGTTGCAGTTCCAGGTGAGCGCGCGCGACTCT
GGCGTGCCGCCTCTGGGCAGCAACGTGACGCTGCAGGTGTTCGTGCTGGACGAGAACGAC
AACGCTCCGGCGCTGCTGACGCCCGGGGCTGGCAGCGCGGGAGGCACAGTGAGCGAGCTG
ATGCCGCGGTCGGTGGGTGCAGGCCACGTGGTGGCGAAGGTGCGCGCGGTGGACGCCGAT
TCGGGCTACAATGCGTGGCTTTCGTATGAATTGCAGCTGGCGGCGGTCGGCGCGCGCATC
CCGTTCCGCGTGGGGCTGTACACTGGCGAGATCAGCACGACGCGCCCTCTGGACGAGGTG
GACGCGCCGCACCACCGCCTTCTGGTGCTGGTGAAGGACCACGGTGAGCCCGCGCTGACG
GCCACGGCAACGGTGCTGTTGTCGCTGGTGGAGAGCGGCCAAGCGCCACAGGCTTCGTCG
AGGGCGTCGGCAGGCGCTGTGGGTCCAGAAGCGGCGCTGGTGGATGTCAATGTTTACTTG
ATCATTGCCATCTGCGCGGTGTCCAGCCTGTTGGTGCTCACGTTGCTGCTGTATACTGCG
CTGCGGTGCTCGGCACCGCCCACCGAGGGCGCGTGCGCGCCGGGCAAGCCCACTCTAGTG
TGCTCCAGCGCGGCAGGGAGTTGGTCGTACTCGCAGCAGAGGCGGCCGAGGGTGTGCTCT
GGGGAGGGCCCGCATAAGACGGACCTCATGGCCTTCAGTCCCAGCCTTCCTCCTTGTCTG
GGTTCTGCAGAGGGAACAGGCCAGAGGGAGGAGGACTCAGAATGCTTGAAAGAGCCACGA
CAGCCCAACCCTGACTGGCGTTACTCTGCCTCCCTGAGAGCAGGCATGCACAGCTCTGTG
CACCTAGAGGAGGCTGGCATTCTACGGGCTGGTCCAGGAGGGCCTGATCAGCAGTGGCCA
ACAGTATCCAGTGCAACACCAGAACCAGAGGCAGGAGAAGTGTCCCCTCCAGTCGGTGCG
GGTGTCAACAGCAACAGCTGGACCTTTAAATACGGACCAGGCAACCCCAAACAATCCGGT
CCCGGTGAGTTGCCCGACAAATTCATTATCCCAGGATCTCCTGCAATCATCTCCATCCGG
CAGGAGCCTACTAACAGCCAAATTGACAAAAGTGACTTCATAACCTTCGGCAAAAAGGAG
GAGACCAAGAAAAAGAAGAAAAAGAAGAAGGGTAACAAGACCCAGGAGAAAAAAGAGAAA
GGGAACAGCACGACTGACAACAGTGACCAGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 950 |
| Molecular Weight
| 102482.4 |
| Theoretical pI
| 4.85 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Protocadherin alpha-13
MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV
PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE
VKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTL
DAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAP
EFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNG
EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIR
EDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA
YELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQ
DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDS
GVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDAD
SGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALT
ATATVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA
LRCSAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCL
GSAEGTGQREEDSECLKEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP
TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR
QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
|
| External Links |
|---|
| GenBank ID Protein
| 9256580 |
| UniProtKB/Swiss-Prot ID
| Q9Y5I0 |
| UniProtKB/Swiss-Prot Entry Name
| PCDAD_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_018904.2 |
| GeneCard ID
| PCDHA13 |
| GenAtlas ID
| PCDHA13 |
| HGNC ID
| HGNC:8667 |
| References |
|---|
| General References
| Not Available |