Identification
HMDB Protein ID CDBP03102
Secondary Accession Numbers Not Available
Name Protocadherin alpha-11
Description Not Available
Synonyms
  1. PCDH-alpha-11
Gene Name PCDHA11
Protein Type Metal Binding
Biological Properties
General Function Involved in calcium ion binding
Specific Function Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain
GO Classification
Component
plasma membrane
membrane
cell part
Function
ion binding
cation binding
metal ion binding
binding
calcium ion binding
Process
cell adhesion
cellular process
cell-cell adhesion
homophilic cell adhesion
Cellular Location
  1. Cell membrane
  2. Single-pass type I membrane protein
Pathways
Gene Properties
Chromosome Location Chromosome:5
Locus 5q31
SNPs PCDHA11
Gene Sequence
>2850 bp
ATGTTTGGTTTTCAGAGAAGGGGATTGGGCACCCCACGACTACAGCTCTGGCTTCTCCTC
CTCGAATTCTGGGAGGTGGGGAGCGGCCAGCTCCACTACTCCGTCTCGGAGGAGGCCAAA
CACGGCACCTTCGTGGGCCGCATCGCGCAGGACCTGGGGCTGGAGCTGGCGGAGCTGGTG
CAGCGCCTGTTCCGGGTGGCGTCCAAAACACATGGGGACCTTCTGGAGGTAAATCTGCAG
AATGGCATTTTGTTTGTGAATTCTCGGATCGACCGCGAGGAGCTGTGCGGGCAGAGCGCG
GAGTGCAGCATCCACCTGGAGGTGATCGTGGACAGGCCGCTGCAGGTTTTCCATGTGAAC
GTGGAGGTGAAGGACATTAACGACAACCCGCCGGTGTTCTCGCTCAGAGAACAAAAGCTG
CTGATTGCGGAATCTAAGCAATCGGACTCGCGTTTTCCACTAGAGGGAGCTTCTGATGCT
GACATTGAAGAGAATGCTCTATTGACCTACAGGCTAAGTAAAAATGAGTATTTTTCTTTA
GATTCACCAACAAATGGTAAGCAGATTAAAAGACTGTCACTTATTTTAAAGAAGTCTCTG
GATAGAGAGAAAACTCCGGAACTTAATTTGCTGCTAACAGCTACAGACGGGGGAAAACCA
GAGCTTACTGGCACCGTTCGGCTGTTAGTCCAAGTCTTGGATGTCAACGACAATGATCCA
GAGTTTGATAAATCAGAATATAAGGTGAGCCTTATGGAAAATGCTGCTAAAGAAACTCTT
GTGCTCAAACTAAACGCCACAGACCGAGACGAAGGAGTCAATGGAGAGGTAACATACTCC
TTAATGTCAATTAAGCCCAATGGAAGACACTTATTTACACTAGATCAAAATAATGGAGAA
GTGAGGGTCAATGGAACTTTAGATTATGAAGAAAACAAGTTTTATAAAATTGAAGTACAG
GCTACAGATAAGGGGACTCCCCCAATGGCAGGTCACTGTACAGTCTGGGTGGAAATCTTG
GACACCAACGATAACTCTCCTGAAGTCGCCGTGACTTCCTTGTCCCTCCCAGTACGAGAG
GACGCTCAGCCCAGCACGGTCATTGCCCTGATCAGCGTGTCTGACCGTGACTCAGGTGTC
AACGGACAGGTGACCTGCTCGCTGACGCCCCACGTTCCCTTCAAGCTGGTGTCCACCTTC
AAGAATTACTACTCGTTGGTGCTGGACAGCGCCCTGGACCGCGAGAACGTGTGGGCCTAT
GAACTGGTGGTGACTGCGCGGGATGGGGGTTCGCCTTCTCTGTGGGCCACGGCCAGGGTA
TCCGTGGAGGTGGCCGACGTGAACGACAATGCGCCTGCGTTCGCACAGCCCGAGTACACC
GTGTTCGTGAAGGAGAACAACCCACCAGGCTGCCACATCTTCACAGTGTCGGCGCGGGAC
GCGGACGCGCAGGAGAACGCGCTGGTGTCCTACTCGCTGGTGGAGCGGCGGTTGGGCGAC
CGCGCGCTGTCGAGCTACGTGTCGGTGCACGCGGAGAGCGGCAAGGTGTACGCGCTGCAG
CCGTTGGACCACGAGGAGCTGGAGCTGCTACAGTTCCAGGTGAGCGCGCGCGATGCGGGC
GTGCCGCCTCTGAGCAGCAACGTGACGCTGCAGGTGTTCGTGCTGGACGAGAACGACAAC
GCGCCGGCACTGCTGGCGACTCAGGCTGGCAGCGCGGGAGGCGCAGTTAACAAGCTAGTA
CCGCGGTCGGTGGGTGCGGGCCACGTGGTGGCGAAGGTGCGCGCAGTGGATGCGGACTCA
GGCTACAACGCGTGGCTTTCATATGAATTGCAGCCGGCGGCGGGCGGCTCGCGCATCCCG
TTCCGCGTGGGGCTGTACACGGGCGAGATAAGCACAACGCGTGCCCTGGACGAGGCAGAC
TCGCCGCGCCACCGACTTCTAGTACTGGTGAAGGATCACGGTGAGCCGGCGCTGACGGCC
ACGGCCACCGTGCTGGTGTCGTTGGTGGAGAGCGGACAGGCGCCAAAGGCCTCTTCCCGG
ACTTTGGCGGGCGCCGCGAGCCCAGAGGCTGCGCTGGTGGATGTCAACGTGTACCTGATC
ATCGCCATCTGCGTGGTGTCCAGCCTCCTGGTACTCACGCTGCTGCTGTATACGGCGCTG
TGGTGGTCGGCAACGCCCACTGAGGGCGCGTGCGCGCCGGGGAAGCCCACGCTGGTGTGC
TCCCGCGCGGTGGGGAGCTGGTCATACTCGCAGCAGAGGCGGCAGAGGGTGTGCTCTGAG
GAGGGCCCACCTAAGACGGACCTCATGGCCTTCAGCCCCAGTCTTCCTCTAGGTCTGAAT
AAAGAGGAGGAAGGGGAAAGACAGGAGCCAGGGTCAAATCACCCCGGACAGCCACGACAG
CCCAACCCTGACTGGCGTTACTCTGCCTCCCTGAGAGCAGGCATGCACAGCTCTGTGCAC
CTAGAGGAGGCTGGCATTCTACGGGCTGGTCCAGGAGGGCCTGATCAGCAGTGGCCAACA
GTATCCAGTGCAACACCAGAACCAGAGGCAGGAGAAGTGTCCCCTCCAGTCGGTGCGGGT
GTCAACAGCAACAGCTGGACCTTTAAATACGGACCAGGCAACCCCAAACAATCCGGTCCC
GGTGAGTTGCCCGACAAATTCATTATCCCAGGATCTCCTGCAATCATCTCCATCCGGCAG
GAGCCTACTAACAGCCAAATTGACAAAAGTGACTTCATAACCTTCGGCAAAAAGGAGGAG
ACCAAGAAAAAGAAGAAAAAGAAGAAGGGTAACAAGACCCAGGAGAAAAAAGAGAAAGGG
AACAGCACGACTGACAACAGTGACCAGTGA
Protein Properties
Number of Residues 949
Molecular Weight 103297.3
Theoretical pI 5.01
Pfam Domain Function
Signals
  • ["1-29"]
Transmembrane Regions
  • ["697-717"]
Protein Sequence
>Protocadherin alpha-11
MFGFQRRGLGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV
QRLFRVASKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVN
VEVKDINDNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSL
DSPTNGKQIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDP
EFDKSEYKVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMSIKPNGRHLFTLDQNNGE
VRVNGTLDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVRE
DAQPSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAY
ELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARD
ADAQENALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAG
VPPLSSNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADS
GYNAWLSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTA
TATVLVSLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTAL
WWSATPTEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLGLN
KEEEGERQEPGSNHPGQPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPT
VSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQ
EPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
GenBank ID Protein 9256576
UniProtKB/Swiss-Prot ID Q9Y5I1
UniProtKB/Swiss-Prot Entry Name PCDAB_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_018902.3
GeneCard ID PCDHA11
GenAtlas ID PCDHA11
HGNC ID HGNC:8665
References
General References Not Available