| Identification |
|---|
| HMDB Protein ID
| CDBP03102 |
| Secondary Accession Numbers
| Not Available |
| Name
| Protocadherin alpha-11 |
| Description
| Not Available |
| Synonyms
|
- PCDH-alpha-11
|
| Gene Name
| PCDHA11 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain |
| GO Classification
|
| Component |
| plasma membrane |
| membrane |
| cell part |
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| calcium ion binding |
| Process |
| cell adhesion |
| cellular process |
| cell-cell adhesion |
| homophilic cell adhesion |
|
| Cellular Location
|
- Cell membrane
- Single-pass type I membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:5 |
| Locus
| 5q31 |
| SNPs
| PCDHA11 |
| Gene Sequence
|
>2850 bp
ATGTTTGGTTTTCAGAGAAGGGGATTGGGCACCCCACGACTACAGCTCTGGCTTCTCCTC
CTCGAATTCTGGGAGGTGGGGAGCGGCCAGCTCCACTACTCCGTCTCGGAGGAGGCCAAA
CACGGCACCTTCGTGGGCCGCATCGCGCAGGACCTGGGGCTGGAGCTGGCGGAGCTGGTG
CAGCGCCTGTTCCGGGTGGCGTCCAAAACACATGGGGACCTTCTGGAGGTAAATCTGCAG
AATGGCATTTTGTTTGTGAATTCTCGGATCGACCGCGAGGAGCTGTGCGGGCAGAGCGCG
GAGTGCAGCATCCACCTGGAGGTGATCGTGGACAGGCCGCTGCAGGTTTTCCATGTGAAC
GTGGAGGTGAAGGACATTAACGACAACCCGCCGGTGTTCTCGCTCAGAGAACAAAAGCTG
CTGATTGCGGAATCTAAGCAATCGGACTCGCGTTTTCCACTAGAGGGAGCTTCTGATGCT
GACATTGAAGAGAATGCTCTATTGACCTACAGGCTAAGTAAAAATGAGTATTTTTCTTTA
GATTCACCAACAAATGGTAAGCAGATTAAAAGACTGTCACTTATTTTAAAGAAGTCTCTG
GATAGAGAGAAAACTCCGGAACTTAATTTGCTGCTAACAGCTACAGACGGGGGAAAACCA
GAGCTTACTGGCACCGTTCGGCTGTTAGTCCAAGTCTTGGATGTCAACGACAATGATCCA
GAGTTTGATAAATCAGAATATAAGGTGAGCCTTATGGAAAATGCTGCTAAAGAAACTCTT
GTGCTCAAACTAAACGCCACAGACCGAGACGAAGGAGTCAATGGAGAGGTAACATACTCC
TTAATGTCAATTAAGCCCAATGGAAGACACTTATTTACACTAGATCAAAATAATGGAGAA
GTGAGGGTCAATGGAACTTTAGATTATGAAGAAAACAAGTTTTATAAAATTGAAGTACAG
GCTACAGATAAGGGGACTCCCCCAATGGCAGGTCACTGTACAGTCTGGGTGGAAATCTTG
GACACCAACGATAACTCTCCTGAAGTCGCCGTGACTTCCTTGTCCCTCCCAGTACGAGAG
GACGCTCAGCCCAGCACGGTCATTGCCCTGATCAGCGTGTCTGACCGTGACTCAGGTGTC
AACGGACAGGTGACCTGCTCGCTGACGCCCCACGTTCCCTTCAAGCTGGTGTCCACCTTC
AAGAATTACTACTCGTTGGTGCTGGACAGCGCCCTGGACCGCGAGAACGTGTGGGCCTAT
GAACTGGTGGTGACTGCGCGGGATGGGGGTTCGCCTTCTCTGTGGGCCACGGCCAGGGTA
TCCGTGGAGGTGGCCGACGTGAACGACAATGCGCCTGCGTTCGCACAGCCCGAGTACACC
GTGTTCGTGAAGGAGAACAACCCACCAGGCTGCCACATCTTCACAGTGTCGGCGCGGGAC
GCGGACGCGCAGGAGAACGCGCTGGTGTCCTACTCGCTGGTGGAGCGGCGGTTGGGCGAC
CGCGCGCTGTCGAGCTACGTGTCGGTGCACGCGGAGAGCGGCAAGGTGTACGCGCTGCAG
CCGTTGGACCACGAGGAGCTGGAGCTGCTACAGTTCCAGGTGAGCGCGCGCGATGCGGGC
GTGCCGCCTCTGAGCAGCAACGTGACGCTGCAGGTGTTCGTGCTGGACGAGAACGACAAC
GCGCCGGCACTGCTGGCGACTCAGGCTGGCAGCGCGGGAGGCGCAGTTAACAAGCTAGTA
CCGCGGTCGGTGGGTGCGGGCCACGTGGTGGCGAAGGTGCGCGCAGTGGATGCGGACTCA
GGCTACAACGCGTGGCTTTCATATGAATTGCAGCCGGCGGCGGGCGGCTCGCGCATCCCG
TTCCGCGTGGGGCTGTACACGGGCGAGATAAGCACAACGCGTGCCCTGGACGAGGCAGAC
TCGCCGCGCCACCGACTTCTAGTACTGGTGAAGGATCACGGTGAGCCGGCGCTGACGGCC
ACGGCCACCGTGCTGGTGTCGTTGGTGGAGAGCGGACAGGCGCCAAAGGCCTCTTCCCGG
ACTTTGGCGGGCGCCGCGAGCCCAGAGGCTGCGCTGGTGGATGTCAACGTGTACCTGATC
ATCGCCATCTGCGTGGTGTCCAGCCTCCTGGTACTCACGCTGCTGCTGTATACGGCGCTG
TGGTGGTCGGCAACGCCCACTGAGGGCGCGTGCGCGCCGGGGAAGCCCACGCTGGTGTGC
TCCCGCGCGGTGGGGAGCTGGTCATACTCGCAGCAGAGGCGGCAGAGGGTGTGCTCTGAG
GAGGGCCCACCTAAGACGGACCTCATGGCCTTCAGCCCCAGTCTTCCTCTAGGTCTGAAT
AAAGAGGAGGAAGGGGAAAGACAGGAGCCAGGGTCAAATCACCCCGGACAGCCACGACAG
CCCAACCCTGACTGGCGTTACTCTGCCTCCCTGAGAGCAGGCATGCACAGCTCTGTGCAC
CTAGAGGAGGCTGGCATTCTACGGGCTGGTCCAGGAGGGCCTGATCAGCAGTGGCCAACA
GTATCCAGTGCAACACCAGAACCAGAGGCAGGAGAAGTGTCCCCTCCAGTCGGTGCGGGT
GTCAACAGCAACAGCTGGACCTTTAAATACGGACCAGGCAACCCCAAACAATCCGGTCCC
GGTGAGTTGCCCGACAAATTCATTATCCCAGGATCTCCTGCAATCATCTCCATCCGGCAG
GAGCCTACTAACAGCCAAATTGACAAAAGTGACTTCATAACCTTCGGCAAAAAGGAGGAG
ACCAAGAAAAAGAAGAAAAAGAAGAAGGGTAACAAGACCCAGGAGAAAAAAGAGAAAGGG
AACAGCACGACTGACAACAGTGACCAGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 949 |
| Molecular Weight
| 103297.3 |
| Theoretical pI
| 5.01 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Protocadherin alpha-11
MFGFQRRGLGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV
QRLFRVASKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVN
VEVKDINDNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSL
DSPTNGKQIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDP
EFDKSEYKVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMSIKPNGRHLFTLDQNNGE
VRVNGTLDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVRE
DAQPSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAY
ELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARD
ADAQENALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAG
VPPLSSNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADS
GYNAWLSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTA
TATVLVSLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTAL
WWSATPTEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLGLN
KEEEGERQEPGSNHPGQPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPT
VSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQ
EPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
|
| External Links |
|---|
| GenBank ID Protein
| 9256576 |
| UniProtKB/Swiss-Prot ID
| Q9Y5I1 |
| UniProtKB/Swiss-Prot Entry Name
| PCDAB_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_018902.3 |
| GeneCard ID
| PCDHA11 |
| GenAtlas ID
| PCDHA11 |
| HGNC ID
| HGNC:8665 |
| References |
|---|
| General References
| Not Available |