| Identification |
|---|
| HMDB Protein ID
| CDBP03101 |
| Secondary Accession Numbers
| Not Available |
| Name
| Protocadherin alpha-10 |
| Description
| Not Available |
| Synonyms
|
- PCDH-alpha-10
|
| Gene Name
| PCDHA10 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain |
| GO Classification
|
| Component |
| membrane |
| cell part |
| plasma membrane |
| Function |
| metal ion binding |
| binding |
| calcium ion binding |
| ion binding |
| cation binding |
| Process |
| cell adhesion |
| cellular process |
| cell-cell adhesion |
| homophilic cell adhesion |
|
| Cellular Location
|
- Isoform 2:Secreted (Potential)
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:5 |
| Locus
| 5q31 |
| SNPs
| PCDHA10 |
| Gene Sequence
|
>2847 bp
ATGGTTTCCAGATGTAGCTGCCTGGGGGTCCAGTGTCTGCTGCTCTCGCTTCTTCTCCTC
GCAGCCTGGGAGGTGGGGAGCGGCCAGCTCCACTACTCAGTCTACGAGGAGGCCAGACAC
GGCACCTTCGTGGGCCGCATCGCGCAGGACCTGGGGCTGGAGCTGGCGGAGCTGGTGCAG
CGCCTGTTCCGGGTGGCGTCCAAAAGACACGGGGACCTTCTGGAGGTAAATCTGCAGAAT
GGCATTTTGTTTGTGAATTCTCGGATTGACCGCGAGGAGCTGTGCGGGCGGAGCGTGGAG
TGCAGCATCCACCTGGAGGTGATCGTGGACAGGCCGCTGCAGGTTTTCCATGTGGACGTG
GAAGTGAAGGACATTAACGACAACCCGCCCAGGTTCTCCGTAACAGAACAAAAGCTCTCA
ATACCTGAATCCAGACTGCTTGACTCTCGATTTCCACTAGAAGGCGCATCTGATGCGGAT
GTTGGAGAGAACGCATTGCTTACTTACAAACTCAGTCCAAATGAGTATTTTGTTCTTGAT
ATTATAAACAAAAAAGACAAAGACAAATTCCCAGTGCTTGTTCTGCGGAAGCTGCTGGAT
CGTGAAGAAAATCCTCAGCTAAAGTTGTTGTTGACAGCAACTGATGGAGGCAAACCTGAA
TTTACCGGATCTGTTTCTCTGCTGATCCTGGTGTTAGATGCCAATGATAACGCCCCTATC
TTTGACAGACCGGTTTATGAAGTTAAGATGTATGAAAATCAAGTGAACCAAACATTAGTA
ATACGGCTCAACGCTTCTGATTCGGATGAAGGAATAAACAAGGAAATGATGTATTCATTT
AGCTCTTTGGTCCCACCCACGATAAGAAGGAAATTTTGGATAAACGAAAGGACGGGAGAA
ATAAAAGTAAATGATGCTATTGACTTTGAGGACAGTAACACTTATGAAATTCATGTAGAT
GTTACAGATAAGGGAAACCCACCTATGGTTGGTCACTGCACGGTCCTAGTGGAACTACTG
GATGAAAATGATAATTCACCTGAGGTGATTGTCACTTCTCTGTCTCTCCCAGTGAAAGAA
GATGCTCAAGTGGGCACCGTCATTGCCCTAATCAGCGTTTCTGACCATGATTCAGGAGCC
AACGGACAGGTCACCTGCTCTCTGACGCCTCACGTTCCGTTCAAGCTGGTGTCCACCTAC
AAGAATTACTACTCATTGGTGCTGGACAGCGCTCTGGACCGCGAGAGGGTGTCGGCCTAT
GAGCTGGTGGTGACCGCGCGGGACGGGGGCTCGCCTCCGCTGTGGGCCACGGCCAGCGTG
TCTGTGGAGGTGGCCGACGTGAACGACAACGCGCCTGCGTTCGCGCAGTCCGAGTACACG
GTGTTCGTGAAGGAGAACAACCCGCCAGGCTGCCACATCTTCACGGTGTCTGCGTGGGAC
GCGGACGCGCAGGAGAACGCCCTGGTGTCCTACTCTCTGGTGGAGCGGCGGTTGGGCGAG
CGCTCGCTGTCGAGCTACGTGTCGGTGCACGCGGAGAGCGGCAAGGTGTACGCGCTGCAG
CCGCTGGACCACGAGGAGCTGGAGCTGCTACAGTTCCAGGTGAGCGCGCGCGATGGGGGC
GTGCCGCCTCTGGGCAGCAACTTGACGCTGCAGGTGTTCGTGCTGGACGAGAACGACAAC
GCTCCCGCGCTGCTGGCGTCTCCCGCTGGCAGCGCGGGCGGTGCAGTCAGTGAGCTGGTG
CTGCGGTCGGTGGTTGCGGGTCACGTGGTGGCTAAGGTGCGCGCAGTGGACGCTGACTCT
GGATACAACGCGTGGCTGTCGTATGAATTGCAGTCGGCGGCGGTTGGTGCACGCATCCCG
TTTCGCGTGGGGCTGTACACGGGCGAGATCAGTACGACGCGCGCTCTGGATGAGACTGAC
TCGCCACGCCAGCGCCTACTGGTGCTGGTGAAGGACCATGGCGAGCCGTCGCTGACGGCC
ACGGCCACTGTGCTTGTGTCGCTTGTGGAGGGCAGCCAGGCACCCAAGGCCTCGTCGCGG
GCTTCAGTGGGCGTGGCGCCCGAGGTGGCCCTGGTGGATGTCAACGTGTACCTGATCATC
GCCATCTGCGCGGTGTCCAGCTTGCTGGTGCTCACGCTGCTGCTGTACACTGCACTGAGG
TGCTCGGCGGCGCCCACCGAGGGCGCATGTGGGCCGGTGAAGCCCACGCTGGTGTGCTCT
AGCGCGGTGGGGAGCTGGTCTTACTCGCAGCAGAGGCGGCAGAGGGTGTGTTCTGGGGAG
GGCCTGCCCAAGGCGGACCTCATGGCCTTCAGCCCCAGCCTTCCACCATGCCCAATGGTA
GATGTGGACGGGGAAGATCAGTCTATTGGAGGGGACCACTCTAGGAAGCCACGACAGCCC
AACCCTGACTGGCGTTACTCTGCCTCCCTGAGAGCAGGCATGCACAGCTCTGTGCACCTA
GAGGAGGCTGGCATTCTACGGGCTGGTCCAGGAGGGCCTGATCAGCAGTGGCCAACAGTA
TCCAGTGCAACACCAGAACCAGAGGCAGGAGAAGTGTCCCCTCCAGTCGGTGCGGGTGTC
AACAGCAACAGCTGGACCTTTAAATACGGACCAGGCAACCCCAAACAATCCGGTCCCGGT
GAGTTGCCCGACAAATTCATTATCCCAGGATCTCCTGCAATCATCTCCATCCGGCAGGAG
CCTACTAACAGCCAAATTGACAAAAGTGACTTCATAACCTTCGGCAAAAAGGAGGAGACC
AAGAAAAAGAAGAAAAAGAAGAAGGGTAACAAGACCCAGGAGAAAAAAGAGAAAGGGAAC
AGCACGACTGACAACAGTGACCAGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 948 |
| Molecular Weight
| 102874.2 |
| Theoretical pI
| 4.8 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Protocadherin alpha-10
MVSRCSCLGVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQ
RLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDV
EVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLD
IINKKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPI
FDRPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGE
IKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKE
DAQVGTVIALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAY
ELVVTARDGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWD
ADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGG
VPPLGSNLTLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADS
GYNAWLSYELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTA
TATVLVSLVEGSQAPKASSRASVGVAPEVALVDVNVYLIIAICAVSSLLVLTLLLYTALR
CSAAPTEGACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPCPMV
DVDGEDQSIGGDHSRKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTV
SSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQE
PTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
|
| External Links |
|---|
| GenBank ID Protein
| 9256574 |
| UniProtKB/Swiss-Prot ID
| Q9Y5I2 |
| UniProtKB/Swiss-Prot Entry Name
| PCDAA_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_018901.2 |
| GeneCard ID
| PCDHA10 |
| GenAtlas ID
| PCDHA10 |
| HGNC ID
| HGNC:8664 |
| References |
|---|
| General References
| Not Available |