Identification
HMDB Protein ID CDBP03100
Secondary Accession Numbers Not Available
Name Protocadherin alpha-9
Description Not Available
Synonyms
  1. PCDH-alpha-9
Gene Name PCDHA9
Protein Type Metal Binding
Biological Properties
General Function Involved in calcium ion binding
Specific Function Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain
GO Classification
Component
cell part
plasma membrane
membrane
Function
ion binding
cation binding
metal ion binding
binding
calcium ion binding
Process
cell adhesion
cellular process
cell-cell adhesion
homophilic cell adhesion
Cellular Location
  1. Cell membrane
  2. Single-pass type I membrane protein
Pathways
Gene Properties
Chromosome Location Chromosome:5
Locus 5q31
SNPs PCDHA9
Gene Sequence
>2853 bp
ATGTTATACTCAAGTCGAGGAGATCCAGAGGGTCAGCCTCTACTGCTCTCGCTTCTGATC
CTCGCAATGTGGGTGGTGGGGAGCGGCCAGCTCCACTACTCCGTCCCGGAGGAAGCCGAA
CACGGCACCTTCGTGGGCCGCATCGCGCAGGACCTGGGGCTGGAGCTGGCGGAGCTGGTG
CCGCGCCTGTTCCAGTTGGATTCCAAAGGCCGCGGGGACCTTCTGGAGGTAAATCTGCAG
AATGGCATTTTGTTTGTGAATTCTCGGATCGACCGCGAGGAGCTGTGCGGGCGGAGCGCG
GAGTGCAGCATCCACCTGGAGGTGATCGTAGACAGGCCGCTGCAGGTTTTCCATGTGGAC
GTGGAGGTGAAGGACATTAACGACAACCCTCCAGTGTTCCCAGCGACACAAAAGAATCTG
TTCATCGCGGAATCCAGGCCGCTTGACTCTCGGTTTCCACTAGAGGGCGCGTCCGATGCA
GATATCGGGGAGAACGCCCTGCTCACTTACAGACTGAGCCCCAATGAGTATTTCTTCCTG
GACGTGCCAACCAGCAACCAGCAGGTAAAACCTCTTGGACTTGTATTACGGAAACTTTTA
GACAGAGAAGAAACTCCGGAGCTTCATTTATTGCTCACGGCCACCGATGGAGGCAAACCC
GAGCTGACTGGCACCGTTCAATTACTCATCACGGTACTGGACAACAATGACAATGCCCCA
GTGTTCGACAGAACCCTGTATACGGTGAAATTACCAGAAAACGTTTCTATCGGAACGCTG
GTGATTCACCCCAATGCCTCAGATTTAGACGAAGGCTTGAATGGGGATATTATTTACTCC
TTCTCCAGTGATGTTTCTCCAGATATAAAATCCAAGTTCCACATGGACCCCTTAAGTGGG
GCAATCACAGTGATAGGACATATGGATTTTGAAGAAAGTAGAGCACACAAGATCCCAGTC
GAGGCTGTCGATAAAGGCTTCCCACCCCTGGCTGGTCATTGTACACTTCTTGTGGAAGTT
GTGGATGTAAATGACAATGCTCCACAGTTGACTATCAAAACGCTCTCGGTTCCTGTAAAA
GAGGACGCACAACTGGGGACAGTTATTGCCCTGATTAGTGTGATCGACCTAGACGCAGAT
GCCAACGGGCAGGTTACCTGCTCCCTGACGCCCCACGTCCCCTTCAAGCTGGTGTCCACC
TACAAGAATTACTACTCGTTGGTGCTGGACAGAGCTCTGGACCGCGAGAGTGTGTCCGCC
TACGAGCTGGTGGTTACCGCGCGGGACGGGGGCTCGCCTTCACTGTGGGCCACGGCCAGG
GTGTCTGTGGAGGTGGCCGACGTGAACGACAACGCACCAGCGTTCGCGCAGTCCGAGTAC
ACGGTGTTCGTGAAGGAGAACAACCCGCCGGGCTGCCACATCTTCACGGTGTCTGCGCGG
GACGCTGACGCGCAGGAGAACGCCCTGGTGTCCTACTCGCTGGTGGAGCGGCGGTTGGGC
GAGCGCTCGCTGTCGAGCTACGTGTCAGTGCACGCGGAGAGCGGCAAGGTGTACGCGCTG
CAGCCGTTGGACCACGAGGAGCTGGAGCTGCTACAGTTCCAGGTGAGCGCGCGCGACGCG
GGCGTGCCGCCTCTGGGCAGCAACGTGACGCTGCAGGTGTTCGTGCTGGACGAGAACGAC
AATGCGCCGGCGCTGCTGACACCTCGGATGAGGGGCACTGACGGCGCAGTGAGCGAGATG
GTGCTGCGGTCGGTGGGCGCCGGCGTAGTGGTGGGGAAGGTGCGCGCAGTGGACGCCGAC
TCGGGCTACAACGCGTGGCTTTCATACGAGCTGCAGCCAGAAACGGCCAGCGCGAGCATC
CCGTTCCGCGTGGGGCTGTACACGGGCGAGATCAGCACAACGCGTGCCCTGGACGAAACG
GACGCACCGCGCCAGCGCCTACTGGTGCTGGTGAAAGACCACGGGGAGCCAGCGCTGACG
GCCACGGCCACTGTGCTGGTGTCGCTGGTGGAGAGCGGCCAGGCGCCAAAGTCATCGTCG
CGGGCGTCAGTGGGTGCCACGGGCCCCGAGGTGACGCTGGTGGATGTCAACGTGTACCTG
ATCATCGCCATCTGCGCGGTGTCTAGCCTGTTGGTTCTCACGCTGCTGCTGTACACTGTG
CTGCGGTGCTCGGCGATGCCCACCGAGGGCGAGTGCGCGCCTGGCAAGCCGACGCTGGTG
TGTTCTAGCGCGGTGGGGAGTTGGTCGTACTCGCAGCAGAGGAGGCAGAGGGTGTGCTCT
GGCGAGGGTAAGCAGAAGACCGACCTCATGGCCTTCAGCCCGGGCCTTTCTCCTTGTGCT
GGATCTACAGAGCGAACGGGAGAACCCTCTGCTTCCTCAGATTCAACTGGGAAGCCACGA
CAGCCCAACCCTGACTGGCGTTACTCTGCCTCCCTGAGAGCAGGCATGCACAGCTCTGTG
CACCTAGAGGAGGCTGGCATTCTACGGGCTGGTCCAGGAGGGCCTGATCAGCAGTGGCCA
ACAGTATCCAGTGCAACACCAGAACCAGAGGCAGGAGAAGTGTCCCCTCCAGTCGGTGCG
GGTGTCAACAGCAACAGCTGGACCTTTAAATACGGACCAGGCAACCCCAAACAATCCGGT
CCCGGTGAGTTGCCCGACAAATTCATTATCCCAGGATCTCCTGCAATCATCTCCATCCGG
CAGGAGCCTACTAACAGCCAAATTGACAAAAGTGACTTCATAACCTTCGGCAAAAAGGAG
GAGACCAAGAAAAAGAAGAAAAAGAAGAAGGGTAACAAGACCCAGGAGAAAAAAGAGAAA
GGGAACAGCACGACTGACAACAGTGACCAGTGA
Protein Properties
Number of Residues 950
Molecular Weight 102401.5
Theoretical pI 4.69
Pfam Domain Function
Signals
  • ["1-29"]
Transmembrane Regions
  • ["698-718"]
Protein Sequence
>Protocadherin alpha-9
MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV
PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD
VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL
DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP
VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG
AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK
EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA
YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR
DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA
GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD
SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT
ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV
LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA
GSTERTGEPSASSDSTGKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP
TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR
QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
GenBank ID Protein 14165425
UniProtKB/Swiss-Prot ID Q9Y5H5
UniProtKB/Swiss-Prot Entry Name PCDA9_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_031857.1
GeneCard ID PCDHA9
GenAtlas ID PCDHA9
HGNC ID HGNC:8675
References
General References Not Available