| Identification |
|---|
| HMDB Protein ID
| CDBP03088 |
| Secondary Accession Numbers
| Not Available |
| Name
| Protocadherin-19 |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| PCDH19 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| Potential calcium-dependent cell-adhesion protein |
| GO Classification
|
| Component |
| membrane |
| cell part |
| plasma membrane |
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| calcium ion binding |
| Process |
| homophilic cell adhesion |
| cell adhesion |
| cellular process |
| cell-cell adhesion |
|
| Cellular Location
|
- Cell membrane
- Single-pass type I membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| PCDH19 |
| Gene Sequence
|
>3447 bp
ATGGAGTCGCTCCTGCTGCCGGTGCTGCTGCTGCTGGCCATACTGTGGACGCAGGCTGCC
GCCCTCATTAATCTCAAGTACTCGGTAGAAGAGGAGCAGCGCGCCGGGACGGTGATTGCC
AACGTGGCCAAAGACGCGCGAGAGGCGGGCTTCGCGCTGGACCCCCGGCAGGCTTCAGCC
TTTCGCGTGGTGTCCAACTCGGCTCCACACCTAGTGGACATCAATCCCAGCTCTGGCCTG
CTGGTCACCAAGCAGAAGATTGACCGTGATCTGCTGTGCCGCCAGAGCCCCAAGTGCATC
ATCTCGCTCGAGGTCATGTCCAGCTCAATGGAAATCTGCGTGATAAAGGTGGAGATCAAG
GACCTGAACGACAATGCGCCCAGTTTCCCGGCAGCACAGATCGAGCTGGAGATCTCGGAG
GCAGCCAGCCCTGGCACGCGCATCCCGCTGGACAGCGCTTACGATCCAGACTCAGGAAGC
TTTGGCGTGCAGACTTACGAGCTCACGCCCAACGAGCTGTTCGGCCTGGAGATCAAGACG
CGCGGCGACGGCTCCCGCTTTGCCGAACTCGTGGTGGAAAAGAGCCTGGACCGCGAGACG
CAGTCGCACTACAGCTTCCGAATCACTGCGCTAGACGGTGGCGACCCGCCGCGCCTGGGC
ACCGTTGGCCTTAGTATCAAGGTGACCGACTCCAATGACAACAACCCGGTGTTTAGCGAG
TCCACCTACGCGGTGAGCGTGCCAGAAAACTCGCCTCCCAACACACCCGTCATCCGCCTC
AACGCCAGCGATCCAGACGAGGGCACCAACGGCCAGGTGGTCTACTCCTTCTATGGCTAC
GTCAACGACCGCACGCGCGAGCTCTTTCAGATCGACCCGCACAGTGGCCTGGTCACTGTC
ACTGGCGCTTTAGACTACGAAGAGGGGCACGTGTACGAACTGGACGTGCAGGCTAAGGAC
TTGGGGCCCAATTCCATCCCGGCACACTGCAAGGTCACCGTCAGCGTGCTGGACACCAAT
GACAATCCGCCGGTCATCAACCTGCTGTCAGTCAACAGTGAGCTTGTGGAGGTCAGCGAG
AGCGCCCCCCCGGGCTACGTGATCGCCTTGGTGCGGGTGTCTGATCGCGACTCAGGCCTC
AATGGACGTGTGCAGTGCCGTTTGCTGGGCAATGTGCCCTTTCGACTGCAGGAATATGAG
AGCTTCTCCACTATTCTGGTGGACGGACGGCTGGACCGCGAGCAGCACGACCAATACAAC
CTCACAATTCAGGCACGCGACGGCGGCGTGCCCATGCTGCAGAGTGCCAAGTCCTTTACC
GTGCTCATCACTGACGAAAATGACAACCACCCGCACTTTTCCAAGCCCTACTACCAGGTC
ATTGTGCAGGAGAACAACACGCCTGGCGCCTATCTGCTCTCTGTGTCTGCTCGCGACCCC
GACCTGGGTCTCAACGGCAGTGTCTCCTACCAGATCGTGCCGTCGCAGGTGCGGGACATG
CCTGTCTTCACCTATGTCTCCATCAATCCCAACTCAGGCGACATCTACGCGCTGCGATCC
TTTAACCACGAGCAGACCAAGGCGTTCGAATTCAAGGTGCTGGCCAAGGACGGCGGCCTT
CCCTCACTGCAAAGCAACGCTACGGTGCGGGTCATCATCCTCGACGTCAACGACAACACC
CCGGTCATCACAGCCCCACCTCTGATTAACGGCACTGCCGAGGTCTACATACCCCGCAAC
TCTGGCATAGGCTACCTGGTGACTGTTGTCAAGGCAGAAGACTACGATGAGGGCGAAAAT
GGCCGAGTCACCTACGACATGACCGAGGGCGACCGCGGCTTCTTTGAAATAGACCAGGTC
AATGGCGAAGTCAGAACCACCCGCACCTTCGGGGAGAGCTCCAAGTCCTCCTATGAGCTT
ATCGTGGTGGCTCACGACCACGGCAAGACATCTCTCTCTGCCTCTGCTCTCGTCCTAATC
TACTTGTCCCCTGCTCTCGATGCCCAAGAGTCAATGGGCTCTGTGAACTTGTCCTTGATT
TTCATTATTGCCCTGGGCTCCATTGCGGGCATCCTCTTTGTAACTATGATCTTCGTGGCA
ATCAAGTGCAAGCGAGACAACAAAGAGATCCGGACCTACAACTGCAGTAATTGTTTAACC
ATCACTTGTCTCCTCGGCTGTTTTATAAAAGGACAAAACAGCAAGTGTCTGCATTGCATC
TCGGTTTCTCCCATTAGCGAGGAGCAAGACAAAAAGACAGAGGAGAAAGTGAGCCTAAGG
GGAAAGAGAATTGCTGAGTACTCCTATGGGCATCAAAAGAAATCAAGCAAGAAGAAAAAA
ATCAGTAAGAATGACATCCGCCTGGTACCCCGGGATGTGGAGGAGACAGACAAGATGAAC
GTTGTCAGTTGCTCTTCCCTGACCTCCTCCCTCAACTATTTTGACTACCACCAGCAGACG
CTGCCCCTGGGCTGCCGCCGCTCTGAGAGCACTTTCCTGAATGTGGAGAACCAGAATACC
CGCAACACCAGTGCTAACCACATCTACCATCACTCTTTCAACAGCCAGGGGCCCCAGCAG
CCTGACCTGATTATCAACGGTGTGCCTCTGCCTGAGACTGAAAACTATTCTTTTGACTCC
AACTACGTGAATAGCCGAGCCCATTTAATCAAGAGCAGCTCCACCTTCAAGGACTTAGAG
GGCAACAGCCTGAAGGATAGTGGACATGAGGAGAGTGACCAAACTGACAGTGAGCATGAT
GTCCAGCGGAGCCTGTATTGTGATACTGCTGTCAACGATGTGCTGAACACCAGTGTGACC
TCCATGGGATCTCAGATGCCTGATCATGATCAGAATGAAGGATTTCATTGCCGGGAAGAA
TGCCGGATTCTTGGCCACTCTGACAGGTGCTGGATGCCCCGGAACCCCATGCCCATCCGT
TCCAAGTCCCCTGAGCATGTGAGGAACATCATCGCGCTGTCTATTGAAGCTACTGCTGCT
GATGTCGAGGCTTATGACGACTGCGGCCCCACCAAACGGACTTTCGCAACCTTTGGGAAA
GATGTCAGCGACCACCCGGCTGAGGAGAGGCCTACCCTGAAAGGCAAGAGGACTGTCGAT
GTGACCATCTGCAGCCCCAAGGTCAACAGCGTTATCCGGGAGGCAGGCAATGGCTGTGAG
GCGATTAGCCCTGTCACCTCCCCCCTCCACCTCAAGAGCTCTCTGCCCACCAAGCCTTCC
GTGTCTTACACCATTGCCCTGGCTCCCCCAGCCCGTGATCTGGAGCAGTATGTCAACAAT
GTCAACAATGGCCCTACTCGTCCCTCTGAAGCTGAGCCCCGTGGAGCTGATAGCGAGAAA
GTCATGCATGAGGTCAGCCCCATTCTGAAGGAAGGTCGCAACAAAGAGTCCCCTGGTGTG
AAGCGTCTGAAGGATATCGTTCTCTAA
|
| Protein Properties |
|---|
| Number of Residues
| 1148 |
| Molecular Weight
| 126251.4 |
| Theoretical pI
| 5.01 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Protocadherin-19
MESLLLPVLLLLAILWTQAAALINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQASA
FRVVSNSAPHLVDINPSSGLLVTKQKIDRDLLCRQSPKCIISLEVMSSSMEICVIKVEIK
DLNDNAPSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKT
RGDGSRFAELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNPVFSE
STYAVSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTV
TGALDYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSE
SAPPGYVIALVRVSDRDSGLNGRVQCRLLGNVPFRLQEYESFSTILVDGRLDREQHDQYN
LTIQARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDP
DLGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGL
PSLQSNATVRVIILDVNDNTPVITAPPLINGTAEVYIPRNSGIGYLVTVVKAEDYDEGEN
GRVTYDMTEGDRGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGKTSLSASALVLI
YLSPALDAQESMGSVNLSLIFIIALGSIAGILFVTMIFVAIKCKRDNKEIRTYNCSNCLT
ITCLLGCFIKGQNSKCLHCISVSPISEEQDKKTEEKVSLRGKRIAEYSYGHQKKSSKKKK
ISKNDIRLVPRDVEETDKMNVVSCSSLTSSLNYFDYHQQTLPLGCRRSESTFLNVENQNT
RNTSANHIYHHSFNSQGPQQPDLIINGVPLPETENYSFDSNYVNSRAHLIKSSSTFKDLE
GNSLKDSGHEESDQTDSEHDVQRSLYCDTAVNDVLNTSVTSMGSQMPDHDQNEGFHCREE
CRILGHSDRCWMPRNPMPIRSKSPEHVRNIIALSIEATAADVEAYDDCGPTKRTFATFGK
DVSDHPAEERPTLKGKRTVDVTICSPKVNSVIREAGNGCEAISPVTSPLHLKSSLPTKPS
VSYTIALAPPARDLEQYVNNVNNGPTRPSEAEPRGADSEKVMHEVSPILKEGRNKESPGV
KRLKDIVL
|
| External Links |
|---|
| GenBank ID Protein
| 296434287 |
| UniProtKB/Swiss-Prot ID
| Q8TAB3 |
| UniProtKB/Swiss-Prot Entry Name
| PCD19_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_001184880.1 |
| GeneCard ID
| PCDH19 |
| GenAtlas ID
| PCDH19 |
| HGNC ID
| HGNC:14270 |
| References |
|---|
| General References
| Not Available |