Identification
HMDB Protein ID CDBP03086
Secondary Accession Numbers Not Available
Name Protocadherin-17
Description Not Available
Synonyms
  1. Protocadherin-68
Gene Name PCDH17
Protein Type Metal Binding
Biological Properties
General Function Involved in calcium ion binding
Specific Function Potential calcium-dependent cell-adhesion protein
GO Classification
Component
membrane
cell part
plasma membrane
Function
ion binding
cation binding
metal ion binding
binding
calcium ion binding
Process
homophilic cell adhesion
cell adhesion
cellular process
cell-cell adhesion
Cellular Location
  1. Cell membrane
  2. Single-pass type I membrane protein
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 13q21.1
SNPs PCDH17
Gene Sequence
>3480 bp
ATGTACCTTTCCATCTGTTGCTGCTTTCTTCTATGGGCCCCTGCCCTCACTCTCAAGAAC
CTCAACTACTCCGTGCCGGAGGAGCAAGGGGCCGGCACGGTGATCGGGAACATCGGCAGG
GATGCTCGACTGCAGCCTGGGCTTCCGCCTGCAGAGCGCGGCGGCGGAGGGCGCAGCAAG
TCGGGTAGCTACCGGGTGCTGGAGAACTCCGCACCGCACCTGCTGGACGTGGACGCAGAC
AGCGGGCTCCTCTACACCAAGCAGCGCATCGACCGCGAGTCCCTGTGCCGCCACAATGCC
AAGTGCCAGCTGTCCCTCGAGGTGTTCGCCAACGACAAGGAGATCTGCATGATCAAGGTA
GAGATCCAGGACATCAACGACAACGCGCCCTCCTTCTCCTCGGACCAGATCGAAATGGAC
ATCTCGGAGAACGCTGCTCCGGGCACCCGCTTCCCCCTCACCAGCGCACATGACCCCGAC
GCCGGCGAGAATGGGCTCCGCACCTACCTGCTCACGCGCGACGATCACGGCCTCTTTGGA
CTGGACGTTAAGTCCCGCGGCGACGGCACCAAGTTCCCAGAACTGGTCATCCAGAAGGCT
CTGGACCGCGAGCAACAGAATCACCATACGCTCGTGCTGACTGCCCTGGACGGTGGCGAG
CCTCCACGTTCCGCCACCGTACAGATCAACGTGAAGGTGATTGACTCCAACGACAACAGC
CCGGTCTTCGAGGCGCCATCCTACTTGGTGGAACTGCCCGAGAACGCTCCGCTGGGTACA
GTGGTCATCGATCTGAACGCCACCGACGCCGATGAAGGTCCCAATGGTGAAGTGCTCTAC
TCTTTCAGCAGCTACGTGCCTGACCGCGTGCGGGAGCTCTTCTCCATCGACCCCAAGACC
GGCCTAATCCGTGTGAAGGGCAATCTGGACTATGAGGAAAACGGGATGCTGGAGATTGAC
GTGCAGGCCCGAGACCTGGGGCCTAACCCTATCCCAGCCCACTGCAAAGTCACGGTCAAG
CTCATCGACCGCAACGACAATGCGCCGTCCATCGGTTTCGTCTCCGTGCGCCAGGGGGCG
CTGAGCGAGGCCGCCCCTCCCGGCACCGTCATCGCCCTGGTGCGGGTCACTGACCGGGAC
TCTGGCAAGAACGGACAGCTGCAGTGTCGGGTCCTAGGCGGAGGAGGGACGGGCGGCGGC
GGGGGCCTGGGCGGGCCCGGGGGTTCCGTCCCCTTCAAGCTTGAGGAGAACTACGACAAC
TTCTACACGGTGGTGACTGACCGCCCGCTGGACCGCGAGACACAAGACGAGTACAACGTG
ACCATCGTGGCGCGGGACGGGGGCTCTCCTCCCCTCAACTCCACCAAGTCGTTCGCGATC
AAGATTCTAGACGAGAACGACAACCCGCCTCGGTTCACCAAAGGGCTCTACGTGCTTCAG
GTGCACGAGAACAACATCCCGGGAGAGTACCTGGGCTCTGTGCTCGCCCAGGATCCCGAC
CTGGGCCAGAACGGCACCGTATCCTACTCTATCCTGCCCTCGCACATCGGCGACGTGTCT
ATCTACACCTATGTGTCTGTGAATCCCACGAACGGGGCCATCTACGCCCTGCGCTCCTTT
AACTTCGAGCAGACCAAGGCTTTTGAGTTCAAGGTGCTTGCTAAGGACTCGGGGGCGCCC
GCGCACTTGGAGAGCAACGCCACGGTGAGGGTGACAGTGCTAGACGTGAATGACAACGCG
CCAGTGATCGTGCTCCCCACGCTGCAGAACGACACCGCGGAGCTGCAGGTGCCGCGCAAC
GCTGGCCTGGGCTATCTGGTGAGCACTGTGCGCGCCCTAGACAGCGACTTCGGCGAGAGC
GGGCGTCTCACCTACGAGATCGTGGACGGCAACGACGACCACCTGTTTGAGATCGACCCG
TCCAGCGGCGAGATCCGCACGCTGCACCCTTTCTGGGAGGACGTGACGCCCGTGGTGGAG
CTGGTGGTGAAGGTGACCGACCACGGCAAGCCTACCCTGTCCGCAGTGGCCAAGCTCATC
ATCCGCTCGGTGAGCGGATCCCTTCCCGAGGGGGTACCACGGGTGAATGGCGAGCAGCAC
CACTGGGACATGTCGCTGCCGCTCATCGTGACTCTGAGCACTATCTCCATCATCCTCCTA
GCGGCCATGATCACCATCGCCGTCAAGTGCAAGCGCGAGAACAAGGAGATCCGCACTTAC
AACTGCCGCATCGCCGAGTACAGCCACCCGCAGCTGGGTGGGGGCAAGGGCAAGAAGAAG
AAGATCAACAAAAATGATATCATGCTGGTGCAGAGCGAAGTGGAGGAGAGGAACGCCATG
AACGTCATGAACGTGGTGAGCAGCCCCTCCCTGGCCACCTCCCCCATGTACTTCGACTAC
CAGACCCGCCTGCCCCTCAGCTCGCCCCGGTCGGAGGTGATGTATCTCAAACCGGCCTCC
AACAACCTGACTGTCCCTCAGGGGCACGCGGGCTGCCACACCAGCTTCACCGGACAAGGG
ACTAATGCAAGCGAGACCCCTGCCACTCGGATGTCCATAATTCAGACAGACAATTTTCCC
GCAGAGCCCAATTACATGGGCAGCAGGCAGCAGTTTGTTCAAAGTAGCTCCACGTTTAAG
GACCCAGAAAGAGCCAGCCTGAGAGACAGTGGGCACGGGGACAGTGATCAGGCTGACAGT
GACCAAGACACTAACAAAGGCTCCTGCTGTGACATGTCTGTTAGGGAGGCACTCAAGATG
AAAACTACTTCAACTAAAAGCCAACCACTTGAACAAGAACCAGAAGAGTGTGTTAATTGC
ACAGATGAATGCCGAGTGCTTGGTCATTCTGACAGGTGCTGGATGCCACAGTTCCCTGCA
GCCAATCAGGCTGAAAATGCAGATTACCGCACAAATCTCTTTGTACCTACAGTTGAAGCT
AATGTTGAGACTGAGACTTACGAAACTGTGAATCCCACTGGGAAAAAGACTTTTTGTACA
TTTGGAAAAGACAAGCGAGAGCACACTATTCTCATTGCCAACGTTAAACCTTATTTAAAA
GCCAAACGTGCCCTGAGCCCTCTCCTCCAAGAGGTCCCCTCAGCATCAAGCAGCCCAACC
AAGGCGTGCATCGAGCCTTGCACCTCAACAAAAGGCTCCCTGGATGGCTGTGAAGCAAAA
CCAGGAGCCCTGGCTGAAGCAAGCAGTCAGTACTTGCCCACTGACAGTCAATATCTGTCA
CCTAGTAAGCAACCAAGAGACCCTCCCTTCATGGCTTCCGATCAGATGGCAAGGGTCTTT
GCAGATGTGCATTCCAGAGCCAGCCGGGATTCCAGTGAGATGGGTGCTGTTCTTGAGCAG
CTTGACCACCCCAACAGGGATCTGGGCAGAGAGTCTGTGGATGCAGAGGAAGTTGTGAGA
GAAATTGATAAGCTTTTGCAAGACTGCCGGGGAAACGACCCTGTGGCTGTGAGAAAGTGA
Protein Properties
Number of Residues 1159
Molecular Weight 126228.3
Theoretical pI 4.81
Pfam Domain Function
Signals
  • ["1-17"]
Transmembrane Regions
  • ["708-728"]
Protein Sequence
>Protocadherin-17
MYLSICCCFLLWAPALTLKNLNYSVPEEQGAGTVIGNIGRDARLQPGLPPAERGGGGRSK
SGSYRVLENSAPHLLDVDADSGLLYTKQRIDRESLCRHNAKCQLSLEVFANDKEICMIKV
EIQDINDNAPSFSSDQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLFG
LDVKSRGDGTKFPELVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNS
PVFEAPSYLVELPENAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDRVRELFSIDPKT
GLIRVKGNLDYEENGMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAPSIGFVSVRQGA
LSEAAPPGTVIALVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKLEENYDN
FYTVVTDRPLDRETQDEYNVTIVARDGGSPPLNSTKSFAIKILDENDNPPRFTKGLYVLQ
VHENNIPGEYLGSVLAQDPDLGQNGTVSYSILPSHIGDVSIYTYVSVNPTNGAIYALRSF
NFEQTKAFEFKVLAKDSGAPAHLESNATVRVTVLDVNDNAPVIVLPTLQNDTAELQVPRN
AGLGYLVSTVRALDSDFGESGRLTYEIVDGNDDHLFEIDPSSGEIRTLHPFWEDVTPVVE
LVVKVTDHGKPTLSAVAKLIIRSVSGSLPEGVPRVNGEQHHWDMSLPLIVTLSTISIILL
AAMITIAVKCKRENKEIRTYNCRIAEYSHPQLGGGKGKKKKINKNDIMLVQSEVEERNAM
NVMNVVSSPSLATSPMYFDYQTRLPLSSPRSEVMYLKPASNNLTVPQGHAGCHTSFTGQG
TNASETPATRMSIIQTDNFPAEPNYMGSRQQFVQSSSTFKDPERASLRDSGHGDSDQADS
DQDTNKGSCCDMSVREALKMKTTSTKSQPLEQEPEECVNCTDECRVLGHSDRCWMPQFPA
ANQAENADYRTNLFVPTVEANVETETYETVNPTGKKTFCTFGKDKREHTILIANVKPYLK
AKRALSPLLQEVPSASSSPTKACIEPCTSTKGSLDGCEAKPGALAEASSQYLPTDSQYLS
PSKQPRDPPFMASDQMARVFADVHSRASRDSSEMGAVLEQLDHPNRDLGRESVDAEEVVR
EIDKLLQDCRGNDPVAVRK
GenBank ID Protein 94538350
UniProtKB/Swiss-Prot ID O14917
UniProtKB/Swiss-Prot Entry Name PCD17_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_001040429.2
GeneCard ID PCDH17
GenAtlas ID PCDH17
HGNC ID HGNC:14267
References
General References Not Available