Identification
HMDB Protein ID CDBP03082
Secondary Accession Numbers Not Available
Name Protocadherin-10
Description Not Available
Synonyms Not Available
Gene Name PCDH10
Protein Type Metal Binding
Biological Properties
General Function Involved in calcium ion binding
Specific Function Potential calcium-dependent cell-adhesion protein
GO Classification
Component
membrane
cell part
plasma membrane
Function
ion binding
cation binding
metal ion binding
binding
calcium ion binding
Process
homophilic cell adhesion
cell adhesion
cellular process
cell-cell adhesion
Cellular Location
  1. Cell membrane
  2. Single-pass type I membrane protein
Pathways
Gene Properties
Chromosome Location Chromosome:4
Locus 4q28.3
SNPs PCDH10
Gene Sequence
>3123 bp
ATGATTGTGCTATTATTGTTTGCCTTGCTCTGGATGGTGGAAGGAGTCTTTTCCCAGCTT
CACTACACGGTACAGGAGGAGCAGGAACATGGCACTTTCGTGGGGAATATCGCTGAAGAT
CTGGGTCTGGACATTACAAAACTTTCGGCTCGCGGGTTTCAGACGGTGCCCAACTCAAGG
ACCCCTTACTTAGACCTCAACCTGGAGACAGGGGTGCTGTACGTGAACGAGAAAATAGAC
CGCGAACAAATCTGCAAACAGAGCCCCTCCTGTGTCCTGCACCTGGAGGTCTTTCTGGAG
AACCCCCTGGAGCTGTTCCAGGTGGAGATCGAGGTGCTGGACATTAATGACAACCCCCCC
TCTTTCCCGGAGCCAGACCTGACGGTGGAAATCTCTGAGAGCGCCACGCCAGGCACTCGC
TTCCCCTTGGAGAGCGCATTCGACCCAGACGTGGGCACCAACTCCTTGCGCGACTACGAG
ATCACCCCCAACAGCTACTTCTCCCTGGACGTGCAGACCCAGGGGGATGGCAACCGATTC
GCTGAGCTGGTGCTGGAGAAGCCACTGGACCGAGAGCAGCAAGCGGTGCACCGCTACGTG
CTGACCGCGGTGGACGGAGGAGGTGGGGGAGGAGTAGGAGAAGGAGGGGGAGGTGGCGGG
GGAGCAGGCCTGCCCCCCCAGCAGCAGCGCACCGGCACGGCCCTACTCACCATCCGAGTG
CTGGACTCCAATGACAATGTGCCCGCTTTCGACCAACCCGTCTACACTGTGTCCCTACCA
GAGAACTCTCCCCCAGGCACTCTCGTGATCCAGCTCAACGCCACCGACCCGGACGAGGGC
CAGAACGGTGAGGTCGTGTACTCCTTCAGCAGCCACATTTCGCCCCGGGCGCGGGAGCTT
TTCGGACTCTCGCCGCGCACTGGCAGACTGGAGGTAAGCGGCGAGTTGGACTATGAAGAG
AGCCCAGTGTACCAAGTGTACGTGCAAGCCAAGGACCTGGGCCCCAACGCCGTGCCTGCG
CACTGCAAGGTGCTAGTGCGAGTACTGGATGCTAATGACAACGCGCCAGAGATCAGCTTC
AGCACCGTGAAGGAAGCGGTGAGTGAGGGCGCGGCGCCCGGCACTGTGGTGGCCCTTTTC
AGCGTGACTGACCGCGACTCAGAGGAGAATGGGCAGGTGCAGTGCGAGCTACTGGGAGAC
GTGCCTTTCCGCCTCAAGTCTTCCTTTAAGAATTACTACACCATCGTTACCGAAGCCCCC
CTGGACCGAGAGGCGGGGGACTCCTACACCCTGACTGTAGTGGCTCGGGACCGGGGCGAG
CCTGCGCTCTCCACCAGTAAGTCGATCCAGGTACAAGTGTCGGATGTGAACGACAACGCG
CCGCGTTTCAGCCAGCCGGTCTACGACGTGTATGTGACTGAAAACAACGTGCCTGGCGCC
TACATCTACGCGGTGAGCGCCACCGACCGGGATGAGGGCGCCAACGCCCAGCTTGCCTAC
TCTATCCTCGAGTGCCAGATCCAGGGCATGAGCGTCTTCACCTACGTTTCTATCAACTCT
GAGAACGGCTACTTGTACGCCCTGCGCTCCTTCGACTATGAGCAGCTGAAGGACTTCAGT
TTTCAGGTGGAAGCCCGGGACGCTGGCAGCCCCCAGGCGCTGGCTGGTAACGCCACTGTC
AACATCCTCATAGTGGATCAAAATGACAACGCCCCTGCCATCGTGGCGCCTCTACCAGGG
CGCAACGGGACTCCAGCGCGTGAGGTGCTGCCCCGCTCGGCGGAGCCGGGTTACCTGCTC
ACCCGCGTGGCCGCCGTGGACGCGGACGACGGCGAGAACGCCCGGCTCACTTACAGCATC
GTGCGTGGCAACGAAATGAACCTCTTTCGCATGGACTGGCGCACCGGGGAGCTGCGCACA
GCACGCCGAGTCCCGGCCAAGCGCGACCCCCAGCGGCCTTATGAGCTGGTGATCGAGGTG
CGCGACCATGGGCAGCCGCCCCTTTCCTCCACCGCCACCCTGGTGGTTCAGCTGGTGGAT
GGCGCCGTGGAGCCCCAGGGCGGGGGCGGGAGCGGAGGCGGAGGGTCAGGAGAGCACCAG
CGCCCCAGTCGCTCTGGCGGCGGGGAAACCTCGCTAGACCTCACCCTCATCCTCATCATC
GCGTTGGGCTCGGTGTCCTTCATCTTCCTGCTGGCCATGATCGTGCTGGCCGTGCGTTGC
CAAAAAGAGAAGAAGCTCAACATCTATACTTGTCTGGCCAGCGATTGCTGCCTCTGCTGC
TGCTGCTGCGGTGGCGGAGGTTCGACCTGCTGTGGCCGCCAAGCCCGGGCGCGCAAGAAG
AAACTCAGCAAGTCAGACATCATGCTGGTGCAGAGCTCCAATGTACCCAGTAACCCGGCC
CAGGTGCCGATAGAGGAGTCCGGGGGCTTTGGCTCCCACCACCACAACCAGAATTACTGC
TATCAGGTATGCCTGACCCCTGAGTCCGCCAAGACCGACCTGATGTTTCTTAAGCCCTGC
AGCCCTTCGCGGAGTACGGACACTGAGCACAACCCCTGCGGGGCCATCGTCACCGGTTAC
ACCGACCAGCAGCCTGATATCATCTCCAACGGAAGCATTTTGTCCAACGAGACTAAACAC
CAGCGAGCAGAGCTCAGCTATCTAGTTGACAGACCTCGCCGAGTTAACAGTTCTGCATTC
CAGGAAGCCGACATAGTAAGCTCTAAGGACAGTGGTCATGGAGACAGTGAACAGGGAGAT
AGTGATCATGATGCCACCAACCGTGCCCAGTCAGCTGGTATGGATCTCTTCTCCAATTGC
ACTGAGGAATGTAAAGCTCTGGGCCACTCAGATCGGTGCTGGATGCCTTCTTTTGTCCCT
TCTGATGGACGCCAGGCTGCTGATTATCGCAGCAATCTGCATGTTCCTGGCATGGACTCT
GTTCCAGACACTGAGGTGTTTGAAACTCCAGAAGCCCAGCCTGGGGCAGAGCGGTCCTTT
TCCACCTTTGGCAAAGAGAAGGCCCTTCACAGCACTCTGGAGAGGAAGGAGCTGGATGGA
CTGCTGACTAATACGCGAGCGCCTTACAAACCACCATATTTGACACGGAAAAGGATATGC
TAG
Protein Properties
Number of Residues 1040
Molecular Weight 112934.9
Theoretical pI 4.49
Pfam Domain Function
Signals
  • ["1-18"]
Transmembrane Regions
  • ["716-736"]
Protein Sequence
>Protocadherin-10
MIVLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSR
TPYLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPP
SFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRF
AELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRV
LDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRAREL
FGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISF
STVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAP
LDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGA
YIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFS
FQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLL
TRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEV
RDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILII
ALGSVSFIFLLAMIVLAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQARARKK
KLSKSDIMLVQSSNVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAKTDLMFLKPC
SPSRSTDTEHNPCGAIVTGYTDQQPDIISNGSILSNETKHQRAELSYLVDRPRRVNSSAF
QEADIVSSKDSGHGDSEQGDSDHDATNRAQSAGMDLFSNCTEECKALGHSDRCWMPSFVP
SDGRQAADYRSNLHVPGMDSVPDTEVFETPEAQPGAERSFSTFGKEKALHSTLERKELDG
LLTNTRAPYKPPYLTRKRIC
GenBank ID Protein 14589916
UniProtKB/Swiss-Prot ID Q9P2E7
UniProtKB/Swiss-Prot Entry Name PCD10_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_032961.1
GeneCard ID PCDH10
GenAtlas ID PCDH10
HGNC ID HGNC:13404
References
General References Not Available