| Identification |
|---|
| HMDB Protein ID
| CDBP03076 |
| Secondary Accession Numbers
| Not Available |
| Name
| P2Y purinoceptor 11 |
| Description
| Not Available |
| Synonyms
|
- P2Y11
|
| Gene Name
| P2RY11 |
| Protein Type
| Receptor |
| Biological Properties |
|---|
| General Function
| Involved in G-protein coupled receptor protein signaling pathway |
| Specific Function
| Receptor for ATP and ADP coupled to G-proteins that activate both phosphatidylinositol-calcium and adenylyl cyclase second messenger systems. Not activated by UTP or UDP |
| GO Classification
|
| Component |
| cell part |
| membrane part |
| intrinsic to membrane |
| integral to membrane |
| Function |
| g-protein coupled receptor activity |
| nucleotide receptor activity, g-protein coupled |
| purinergic nucleotide receptor activity, g-protein coupled |
| receptor activity |
| transmembrane receptor activity |
| molecular transducer activity |
| signal transducer activity |
| Process |
| signaling |
| signaling pathway |
| cell surface receptor linked signaling pathway |
| g-protein coupled receptor protein signaling pathway |
|
| Cellular Location
|
- Cell membrane
- Multi-pass membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 19p13.2 |
| SNPs
| P2RY11 |
| Gene Sequence
|
>1125 bp
ATGGCAGCCAACGTCTCGGGTGCCAAGTCCTGCCCTGCCAACTTCTTGGCAGCTGCCGAC
GACAAACTCAGTGGGTTCCAGGGGGACTTCCTGTGGCCCATACTGGTGGTTGAGTTCCTG
GTGGCCGTGGCCAGCAATGGCCTGGCCCTGTACCGCTTCAGCATCCGGAAGCAGCGCCCA
TGGCACCCCGCCGTGGTCTTCTCTGTCCAGCTGGCAGTCAGCGACCTGCTCTGCGCCCTG
ACGCTGCCCCCGCTGGCCGCCTACCTCTATCCCCCCAAGCACTGGCGCTATGGGGAGGCC
GCGTGCCGCCTGGAGCGCTTCCTCTTCACCTGCAACCTGCTGGGCAGCGTCATCTTCATC
ACCTGCATCAGCCTCAACCGCTACCTGGGCATCGTGCACCCCTTCTTCGCCCGAAGCCAC
CTGCGACCCAAGCACGCCTGGGCCGTGAGCGCTGCCGGCTGGGTCCTGGCCGCCCTGCTG
GCCATGCCCACACTCAGCTTCTCCCACCTGAAGAGGCCGCAGCAGGGGGCGGGCAACTGC
AGCGTGGCCAGGCCCGAGGCCTGCATCAAGTGTCTGGGGACAGCAGACCACGGGCTGGCG
GCCTACAGAGCGTATAGCCTGGTGCTGGCGGGGTTGGGCTGCGGCCTGCCGCTGCTGCTC
ACGCTGGCAGCCTACGGCGCCCTCGGGCGGGCCGTGCTACGCAGCCCAGGCATGACTGTG
GCCGAGAAGCTGCGTGTGGCAGCGTTGGTGGCCAGTGGTGTGGCCCTCTACGCCAGCTCC
TATGTGCCCTACCACATCATGCGGGTGCTCAACGTGGATGCTCGGCGGCGCTGGAGCACC
CGCTGCCCGAGCTTTGCAGACATAGCCCAGGCCACAGCAGCCCTGGAGCTGGGGCCCTAC
GTGGGCTACCAGGTGATGCGGGGCCTCATGCCCCTGGCCTTCTGTGTCCACCCTCTACTC
TACATGGCCGCAGTGCCCAGCCTGGGCTGCTGCTGCCGACACTGCCCCGGCTACAGGGAC
AGCTGGAACCCAGAGGACGCCAAGAGCACTGGCCAAGCCCTGCCCCTCAATGCCACAGCC
GCCCCTAAACCGTCAGAGCCCCAGTCCCGTGAGCTGAGCCAATGA
|
| Protein Properties |
|---|
| Number of Residues
| 374 |
| Molecular Weight
| 40344.8 |
| Theoretical pI
| 9.28 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
- ["30-50", "65-85", "117-137", "147-167", "207-227", "246-266", "309-329"]
|
| Protein Sequence
|
>P2Y purinoceptor 11
MAANVSGAKSCPANFLAAADDKLSGFQGDFLWPILVVEFLVAVASNGLALYRFSIRKQRP
WHPAVVFSVQLAVSDLLCALTLPPLAAYLYPPKHWRYGEAACRLERFLFTCNLLGSVIFI
TCISLNRYLGIVHPFFARSHLRPKHAWAVSAAGWVLAALLAMPTLSFSHLKRPQQGAGNC
SVARPEACIKCLGTADHGLAAYRAYSLVLAGLGCGLPLLLTLAAYGALGRAVLRSPGMTV
AEKLRVAALVASGVALYASSYVPYHIMRVLNVDARRRWSTRCPSFADIAQATAALELGPY
VGYQVMRGLMPLAFCVHPLLYMAAVPSLGCCCRHCPGYRDSWNPEDAKSTGQALPLNATA
APKPSEPQSRELSQ
|
| External Links |
|---|
| GenBank ID Protein
| 23463303 |
| UniProtKB/Swiss-Prot ID
| Q96G91 |
| UniProtKB/Swiss-Prot Entry Name
| P2Y11_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_002566.4 |
| GeneCard ID
| P2RY11 |
| GenAtlas ID
| P2RY11 |
| HGNC ID
| HGNC:8540 |
| References |
|---|
| General References
| Not Available |