Identification
HMDB Protein ID CDBP03069
Secondary Accession Numbers Not Available
Name Nucleobindin-1
Description Not Available
Synonyms
  1. CALNUC
Gene Name NUCB1
Protein Type Metal Binding
Biological Properties
General Function Involved in calcium ion binding
Specific Function Major calcium-binding protein of the Golgi. May have a role in calcium homeostasis
GO Classification
Function
ion binding
cation binding
metal ion binding
binding
calcium ion binding
Cellular Location
  1. Cytoplasm
  2. Peripheral membrane protein
  3. Golgi apparatus
  4. Lumenal side
  5. cis-Golgi network membrane
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 19q13.33
SNPs NUCB1
Gene Sequence
>1386 bp
ATGCCTCCCTCTGGGCCCCGAGGAACCCTCCTTCTGTTGCCGCTGCTGCTGCTGCTCCTG
CTTCGCGCCGTGCTGGCTGTCCCCCTGGAGCGAGGGGCGCCCAACAAGGAGGAGACCCCT
GCGACTGAGAGTCCCGACACAGGCCTGTACTACCACCGGTACCTCCAGGAGGTCATCGAT
GTACTGGAGACGGATGGGCATTTCCGAGAGAAGCTGCAGGCTGCCAATGCGGAGGACATC
AAGAGCGGGAAGCTGAGCCGAGAGCTGGACTTTGTCAGCCACCACGTCCGCACCAAGCTG
GATGAGCTCAAGCGACAGGAGGTGTCACGGCTGCGGATGCTGCTCAAGGCCAAGATGGAC
GCCGAGCAGGATCCCAATGTACAGGTGGATCATCTGAATCTCCTGAAACAGTTTGAACAC
CTGGACCCTCAGAACCAGCATACATTCGAGGCCCGCGACCTGGAGCTGCTGATCCAGACG
GCCACCCGGGACCTTGCCCAGTACGACGCAGCCCATCATGAAGAGTTCAAGCGCTACGAG
ATGCTTAAGGAACACGAGAGACGGCGTTATCTGGAGTCACTGGGAGAGGAGCAGAGAAAG
GAGGCGGAGAGGAAGCTGGAAGAGCAACAGCGCCGGCACCGCGAGCACCCTAAAGTCAAC
GTGCCTGGCAGCCAAGCCCAGTTGAAGGAGGTGTGGGAGGAGCTGGATGGACTGGACCCC
AACAGGTTTAACCCCAAGACCTTCTTCATACTGCATGATATCAACAGTGATGGTGTCCTG
GATGAGCAGGAGCTGGAGGCACTCTTCACCAAGGAGCTGGAGAAAGTGTACGACCCAAAG
AATGAGGAGGACGACATGCGGGAGATGGAGGAGGAGCGACTGCGCATGCGGGAGCATGTG
ATGAAGAATGTGGACACCAACCAGGACCGCCTCGTGACCCTGGAGGAGTTCCTCGCATCC
ACTCAGAGGAAGGAGTTTGGGGACACCGGGGAGGGCTGGGAGACAGTGGAGATGCACCCT
GCCTACACCGAGGAAGAGCTGAGGCGCTTTGAAGAGGAGCTGGCTGCCCGGGAGGCAGAG
CTGAATGCCAAGGCCCAGCGCCTCAGCCAGGAGACAGAGGCTCTAGGGCGGTCCCAGGGC
CGCCTGGAGGCCCAGAAGAGAGAGCTGCAGCAGGCTGTGCTGCACATGGAGCAGCGGAAG
CAGCAGCAGCAGCAGCAGCAAGGCCACAAGGCCCCGGCTGCCCACCCTGAGGGGCAGCTC
AAGTTCCACCCAGACACAGACGATGTACCTGTCCCAGCTCCAGCCGGTGACCAGAAGGAG
GTGGACACTTCAGAAAAGAAACTTCTCGAGCGGCTCCCTGAGGTTGAGGTGCCCCAGCAT
CTGTGA
Protein Properties
Number of Residues 461
Molecular Weight 53879.0
Theoretical pI 4.92
Pfam Domain Function Not Available
Signals
  • ["1-26"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>Nucleobindin-1
MPPSGPRGTLLLLPLLLLLLLRAVLAVPLERGAPNKEETPATESPDTGLYYHRYLQEVID
VLETDGHFREKLQAANAEDIKSGKLSRELDFVSHHVRTKLDELKRQEVSRLRMLLKAKMD
AEQDPNVQVDHLNLLKQFEHLDPQNQHTFEARDLELLIQTATRDLAQYDAAHHEEFKRYE
MLKEHERRRYLESLGEEQRKEAERKLEEQQRRHREHPKVNVPGSQAQLKEVWEELDGLDP
NRFNPKTFFILHDINSDGVLDEQELEALFTKELEKVYDPKNEEDDMREMEEERLRMREHV
MKNVDTNQDRLVTLEEFLASTQRKEFGDTGEGWETVEMHPAYTEEELRRFEEELAAREAE
LNAKAQRLSQETEALGRSQGRLEAQKRELQQAVLHMEQRKQQQQQQQGHKAPAAHPEGQL
KFHPDTDDVPVPAPAGDQKEVDTSEKKLLERLPEVEVPQHL
GenBank ID Protein 189067873
UniProtKB/Swiss-Prot ID Q02818
UniProtKB/Swiss-Prot Entry Name NUCB1_HUMAN
PDB IDs
GenBank Gene ID AK315422
GeneCard ID NUCB1
GenAtlas ID NUCB1
HGNC ID HGNC:8043
References
General References Not Available