Showing Protein Nuclear factor of activated T-cells, cytoplasmic 3 (CDBP03054)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 compounds
Identification
HMDB Protein ID CDBP03054
Secondary Accession Numbers Not Available
Name Nuclear factor of activated T-cells, cytoplasmic 3
Description Not Available
Synonyms
  1. NF-AT4
  2. NF-ATc3
  3. NFATc3
  4. NFATx
  5. T-cell transcription factor NFAT4
Gene Name NFATC3
Protein Type Transcription Factor
Biological Properties
General Function Involved in sequence-specific DNA binding transcription factor activity
Specific Function Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2
GO Classification
Component
organelle
membrane-bounded organelle
intracellular membrane-bounded organelle
nucleus
Function
sequence-specific dna binding transcription factor activity
Process
biological regulation
regulation of biological process
regulation of metabolic process
regulation of macromolecule metabolic process
regulation of gene expression
regulation of transcription
regulation of transcription, dna-dependent
Cellular Location
  1. Nucleus
  2. Cytoplasm
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 16q22.2
SNPs NFATC3
Gene Sequence 
>3228 bp
ATGACTACTGCAAACTGTGGCGCCCACGACGAGCTCGACTTCAAACTCGTCTTTGGCGAG
GACGGGGCGCCGGCGCCGCCGCCCCCGGGCTCGCGGCCTGCAGATCTTGAGCCAGATGAT
TGTGCATCCATTTACATCTTTAATGTAGATCCACCTCCATCTACTTTAACCACACCACTT
TGCTTACCACATCATGGATTACCGTCTCACTCTTCTGTTTTGTCACCATCGTTTCAGCTC
CAAAGTCACAAAAACTATGAAGGAACTTGTGAGATTCCTGAATCTAAATATAGCCCATTA
GGTGGTCCCAAACCCTTTGAGTGCCCAAGTATTCAAATTACATCTATCTCTCCTAACTGT
CATCAAGAATTAGATGCACATGAAGATGACCTACAGATAAATGACCCAGAACGGGAATTT
TTGGAAAGGCCTTCTAGAGATCATCTCTATCTTCCTCTTGAGCCATCCTACCGGGAGTCT
TCTCTTAGTCCTAGTCCTGCCAGCAGCATCTCTTCTAGGAGTTGGTTCTCTGATGCATCT
TCTTGTGAATCGCTTTCACATATTTATGATGATGTGGACTCAGAGTTGAATGAAGCTGCA
GCCCGATTTACCCTTGGATCCCCTCTGACTTCTCCTGGTGGCTCTCCAGGGGGCTGCCCT
GGAGAAGAAACTTGGCATCAACAGTATGGACTTGGACACTCATTATCACCCAGGCAATCT
CCTTGCCACTCTCCTAGATCCAGTGTCACTGATGAGAATTGGCTGAGCCCCAGGCCAGCC
TCAGGACCCTCATCAAGGCCCACATCCCCCTGTGGGAAACGGAGGCACTCCAGTGCTGAA
GTTTGTTATGCTGGGTCCCTTTCACCCCATCACTCACCTGTTCCTTCACCTGGTCACTCC
CCCAGGGGAAGTGTGACAGAAGATACGTGGCTCAATGCTTCTGTCCATGGTGGGTCAGGC
CTTGGCCCTGCAGTTTTTCCATTTCAGTACTGTGTAGAGACTGACATCCCTCTCAAAACA
AGGAAAACTTCTGAAGATCAAGCTGCCATACTACCAGGAAAATTAGAGCTGTGTTCAGAT
GACCAAGGGAGTTTATCACCAGCCCGGGAGACTTCAATAGATGATGGCCTTGGATCTCAG
TATCCTTTAAAGAAAGATTCATGTGGTGATCAGTTTCTTTCAGTTCCTTCACCCTTTACC
TGGAGCAAACCAAAGCCTGGCCACACCCCTATATTTCGCACATCTTCATTACCTCCACTA
GACTGGCCTTTACCAGCTCATTTTGGACAATGTGAACTGAAAATAGAAGTGCAACCTAAA
ACTCATCATCGAGCCCATTATGAAACTGAAGGTAGCCGAGGGGCAGTAAAAGCATCTACT
GGGGGACATCCTGTTGTGAAGCTCCTGGGCTATAACGAAAAGCCAATAAATCTACAAATG
TTTATTGGGACAGCAGATGATCGATATTTACGACCTCATGCATTTTACCAGGTGCATCGA
ATCACTGGGAAGACAGTCGCTACTGCAAGCCAAGAGATAATAATTGCCAGTACAAAAGTT
CTGGAAATTCCACTTCTTCCTGAAAATAATATGTCAGCCAGTATTGATTGTGCAGGTATT
TTGAAACTCCGCAATTCAGATATAGAACTTCGAAAAGGAGAAACTGATATTGGCAGAAAG
AATACTAGAGTACGACTTGTGTTTCGTGTACACATCCCACAGCCCAGTGGAAAAGTCCTT
TCTCTGCAGATAGCCTCTATACCCGTTGAGTGCTCCCAGCGGTCTGCTCAAGAACTTCCT
CATATTGAGAAGTACAGTATCAACAGTTGTTCTGTAAATGGAGGTCATGAAATGGTTGTG
ACTGGATCTAATTTTCTTCCAGAATCCAAAATCATTTTTCTTGAAAAAGGACAAGATGGA
CGACCTCAGTGGGAGGTAGAAGGGAAGATAATCAGGGAAAAATGTCAAGGGGCTCACATT
GTCCTTGAAGTTCCTCCATATCATAACCCAGCAGTTACAGCTGCAGTGCAGGTGCACTTT
TATCTTTGCAATGGCAAGAGGAAAAAAAGCCAGTCTCAACGTTTTACTTATACACCAGTT
TTGATGAAGCAAGAACACAGAGAAGAGATTGATTTGTCTTCAGTTCCATCTTTGCCTGTG
CCTCATCCTGCTCAGACCCAGAGGCCTTCCTCTGATTCAGGGTGTTCACATGACAGTGTA
CTGTCAGGACAGAGAAGTTTGATTTGCTCCATCCCACAAACATATGCATCCATGGTGACC
TCATCCCATCTGCCACAGTTGCAGTGTAGAGATGAGAGTGTTAGTAAAGAACAGCATATG
ATTCCTTCTCCAATTGTACACCAGCCTTTTCAAGTCACACCAACACCTCCTGTGGGGTCT
TCCTATCAGCCTATGCAAACTAATGTTGTGTACAATGGACCAACTTGTCTTCCTATTAAT
GCTGCCTCTAGTCAAGAATTTGATTCAGTTTTGTTTCAGCAGGATGCAACTCTTTCTGGT
TTAGTGAATCTTGGCTGTCAACCACTGTCATCCATACCATTTCATTCTTCAAATTCAGGC
TCAACAGGACATCTCTTAGCCCATACACCTCATTCTGTGCATACCCTGCCTCATCTGCAA
TCAATGGGATATCATTGTTCAAATACAGGACAAAGATCTCTTTCTTCTCCAGTGGCTGAC
CAGATTACAGGTCAGCCTTCGTCTCAGTTACAACCTATTACATATGGTCCTTCACATTCA
GGGTCTGCTACAACAGCTTCCCCAGCAGCTTCTCATCCCTTGGCTAGTTCACCGCTTTCT
GGGCCACCATCTCCTCAGCTTCAGCCTATGCCTTACCAATCTCCTAGCTCAGGAACTGCC
TCATCACCGTCTCCAGCCACCAGAATGCATTCTGGACAGCACTCAACTCAAGCACAAAGT
ACGGGCCAGGGGGGTCTTTCTGCACCTTCATCCTTAATATGTCACAGTTTGTGTGATCCA
GCGTCATTTCCACCTGATGGGGCAACTGTGAGCATTAAACCTGAACCAGAAGATCGAGAG
CCTAACTTTGCAACCATTGGTCTGCAGGACATCACTTTAGATGATGTGAACGAGATAATT
GGGAGAGACATGTCCCAGATTTCTGTTTCCCAAGGAGCAGGGGTGAGCAGGCAGGCTCCC
CTCCCGAGTCCTGAGTCCCTGGATTTAGGAAGATCTGATGGGCTCTAA
Protein Properties
Number of Residues 1075
Molecular Weight 115592.8
Theoretical pI 6.35
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence 
>Nuclear factor of activated T-cells, cytoplasmic 3
MTTANCGAHDELDFKLVFGEDGAPAPPPPGSRPADLEPDDCASIYIFNVDPPPSTLTTPL
CLPHHGLPSHSSVLSPSFQLQSHKNYEGTCEIPESKYSPLGGPKPFECPSIQITSISPNC
HQELDAHEDDLQINDPEREFLERPSRDHLYLPLEPSYRESSLSPSPASSISSRSWFSDAS
SCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCPGEETWHQQYGLGHSLSPRQS
PCHSPRSSVTDENWLSPRPASGPSSRPTSPCGKRRHSSAEVCYAGSLSPHHSPVPSPGHS
PRGSVTEDTWLNASVHGGSGLGPAVFPFQYCVETDIPLKTRKTSEDQAAILPGKLELCSD
DQGSLSPARETSIDDGLGSQYPLKKDSCGDQFLSVPSPFTWSKPKPGHTPIFRTSSLPPL
DWPLPAHFGQCELKIEVQPKTHHRAHYETEGSRGAVKASTGGHPVVKLLGYNEKPINLQM
FIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLLPENNMSASIDCAGI
LKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELP
HIEKYSINSCSVNGGHEMVVTGSNFLPESKIIFLEKGQDGRPQWEVEGKIIREKCQGAHI
VLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTPVLMKQEHREEIDLSSVPSLPV
PHPAQTQRPSSDSGCSHDSVLSGQRSLICSIPQTYASMVTSSHLPQLQCRDESVSKEQHM
IPSPIVHQPFQVTPTPPVGSSYQPMQTNVVYNGPTCLPINAASSQEFDSVLFQQDATLSG
LVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHSVHTLPHLQSMGYHCSNTGQRSLSSPVAD
QITGQPSSQLQPITYGPSHSGSATTASPAASHPLASSPLSGPPSPQLQPMPYQSPSSGTA
SSPSPATRMHSGQHSTQAQSTGQGGLSAPSSLICHSLCDPASFPPDGATVSIKPEPEDRE
PNFATIGLQDITLDDVNEIIGRDMSQISVSQGAGVSRQAPLPSPESLDLGRSDGL
GenBank ID Protein 27886561
UniProtKB/Swiss-Prot ID Q12968
UniProtKB/Swiss-Prot Entry Name NFAC3_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_173165.2
GeneCard ID NFATC3
GenAtlas ID NFATC3
HGNC ID HGNC:7777
References
General References Not Available