Showing Protein Matrix metalloproteinase-26 (CDBP03025)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 compounds
Identification
HMDB Protein ID CDBP03025
Secondary Accession Numbers Not Available
Name Matrix metalloproteinase-26
Description Not Available
Synonyms
  1. Endometase
  2. MMP-26
  3. Matrilysin-2
Gene Name MMP26
Protein Type Enzyme
Biological Properties
General Function Involved in metalloendopeptidase activity
Specific Function May hydrolyze collagen type IV, fibronectin, fibrinogen, beta-casein, type I gelatin and alpha-1 proteinase inhibitor. Is also able to activates progelatinase B
GO Classification
Component
extracellular region part
extracellular matrix
Function
endopeptidase activity
ion binding
cation binding
metal ion binding
binding
catalytic activity
hydrolase activity
transition metal ion binding
zinc ion binding
metalloendopeptidase activity
peptidase activity
peptidase activity, acting on l-amino acid peptides
metallopeptidase activity
Process
proteolysis
metabolic process
macromolecule metabolic process
protein metabolic process
Cellular Location
  1. Secreted
  2. extracellular space
  3. extracellular matrix
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 11p15
SNPs MMP26
Gene Sequence 
>786 bp
ATGCAGCTCGTCATCTTAAGAGTTACTATCTTCTTGCCCTGGTGTTTCGCCGTTCCAGTG
CCCCCTGCTGCAGACCATAAAGGATGGGACTTTGTTGAGGGCTATTTCCATCAATTTTTC
CTGACCAAGAAGGAGTCGCCACTCCTTACCCAGGAGACACAAACACAGCTCCTGCAACAA
TTCCATCGGAATGGGACAGACCTACTTGACATACAGATGCATGCTCTGCTACACCAGCCC
CACTGTGGGGTGCCTGATGGGTCCGACACCTCCATCTCGCCAGGAAGATGCAAGTGGAAT
AAGCACACTCTAACTTACAGGATTATCAATTACCCACATGATATGAAGCCATCCGCAGTG
AAAGACAGTATATATAATGCAGTTTCCATCTGGAGCAATGTGACCCCTTTGATATTCCAG
CAAGTGCAGAATGGAGATGCAGACATCAAGGTTTCTTTCTGGCAGTGGGCCCATGAAGAT
GGTTGGCCCTTTGATGGGCCAGGTGGTATCTTAGGCCATGCCTTTTTACCAAATTCTGGA
AATCCTGGAGTTGTCCATTTTGACAAGAATGAACACTGGTCAGCTTCAGACACTGGATAT
AATCTGTTCCTGGTTGCAACTCATGAGATTGGGCATTCTTTGGGCCTGCAGCACTCTGGG
AATCAGAGCTCCATAATGTACCCCACTTACTGGTATCACGACCCTAGAACCTTCCAGCTC
AGTGCCGATGATATCCAAAGGATCCAGCATTTGTATGGAGAAAAATGTTCATCTGACATA
CCTTAA
Protein Properties
Number of Residues 261
Molecular Weight 29708.3
Theoretical pI 6.45
Pfam Domain Function
Signals
  • ["1-17"]
Transmembrane Regions
  • ["None"]
Protein Sequence 
>Matrix metalloproteinase-26
MQLVILRVTIFLPWCFAVPVPPAADHKGWDFVEGYFHQFFLTKKESPLLTQETQTQLLQQ
FHRNGTDLLDMQMHALLHQPHCGVPDGSDTSISPGRCKWNKHTLTYRIINYPHDMKPSAV
KDSIYNAVSIWSNVTPLIFQQVQNGDADIKVSFWQWAHEDGWPFDGPGGILGHAFLPNSG
NPGVVHFDKNEHWSASDTGYNLFLVATHEIGHSLGLQHSGNQSSIMYPTYWYHDPRTFQL
SADDIQRIQHLYGEKCSSDIP
GenBank ID Protein 8843950
UniProtKB/Swiss-Prot ID Q9NRE1
UniProtKB/Swiss-Prot Entry Name MMP26_HUMAN
PDB IDs Not Available
GenBank Gene ID AF230354
GeneCard ID MMP26
GenAtlas ID MMP26
HGNC ID HGNC:14249
References
General References Not Available