Identification |
HMDB Protein ID
| CDBP03009 |
Secondary Accession Numbers
| Not Available |
Name
| Mitochondrial intermediate peptidase |
Description
| Not Available |
Synonyms
|
- MIP
|
Gene Name
| MIPEP |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in metalloendopeptidase activity |
Specific Function
| Cleaves proteins, imported into the mitochondrion, to their mature size |
GO Classification
|
Function |
endopeptidase activity |
catalytic activity |
hydrolase activity |
metalloendopeptidase activity |
peptidase activity |
peptidase activity, acting on l-amino acid peptides |
Process |
metabolic process |
macromolecule metabolic process |
protein metabolic process |
proteolysis |
|
Cellular Location
|
- Mitochondrion matrix
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:1 |
Locus
| 13q12 |
SNPs
| MIPEP |
Gene Sequence
|
>2142 bp
ATGCTGTGCGTCGGAAGGCTGGGCGGCTTGGGAGCCAGAGCAGCAGCTCTGCCGCCCCGC
CGGGCGGGCCGGGGAAGCCTCGAAGCCGGGATCCGGGCCCGAAGGGTCAGCACCAGCTGG
TCTCCCGTGGGCGCCGCCTTCAATGTCAAGCCCCAGGGCAGCCGCTTGGACCTGTTCGGC
GAGCGCCGGGGTCTTTTTGGAGTTCCTGAGCTGAGTGCCCCAGAAGGATTTCATATTGCA
CAAGAAAAAGCCTTGAGAAAGACAGAATTGCTTGTGGACCGTGCATGTTCCACCCCACCT
GGGCCCCAGACCGTGCTGATCTTCGATGAGCTCTCGGATTCCTTATGCAGAGTGGCCGAC
TTGGCTGATTTTGTGAAAATCGCTCACCCTGAGCCAGCATTCAGAGAAGCTGCGGAAGAA
GCTTGTAGAAGTATTGGCACCATGGTAGAGAAGTTGAACACAAATGTGGATTTATATCAA
AGTTTGCAAAAATTACTAGCTGATAAAAAACTTGTGGATTCCCTTGATCCAGAAACAAGG
CGAGTGGCTGAACTGTTTATGTTTGATTTTGAAATTAGTGGAATCCATCTAGACAAAGAA
AAGCGTAAAAGAGCAGTGGACCTCAATGTTAAAATCTTGGATTTGAGTAGTACATTTCTT
ATGGGAACCAATTTTCCCAACAAGATTGAGAAGCATCTCTTACCAGAACACATTCGTCGT
AACTTTACATCTGCTGGGGATCATATCATAATTGATGGTCTCCACGCAGAATCACCAGAT
GACTTGGTGCGAGAAGCTGCTTATAAAATTTTTCTTTATCCCAATGCTGGTCAATTGAAA
TGTTTAGAAGAATTGCTCAGCAGCAGAGATCTTCTGGCAAAGTTGGTGGGGTATTCCACG
TTTTCTCACAGGGCTCTCCAAGGAACGATAGCTAAAAATCCAGAGACTGTCATGCAGTTC
CTTGAAAAACTATCTGACAAACTTTCTGAAAGAACTCTGAAAGATTTTGAGATGATACGA
GGGATGAAAATGAAACTGAATCCTCAAAATTCCGAAGTAATGCCCTGGGACCCCCCTTAC
TACAGTGGTGTGATTCGTGCAGAAAGGTATAATATTGAGCCCAGCCTATATTGCCCGTTT
TTCTCTCTTGGAGCATGCATGGAAGGCCTGAATATTTTGCTTAACAGACTGTTGGGGATT
TCATTATATGCAGAGCAGCCTGCAAAAGGAGAGGTGTGGAGCGAAGATGTCCGAAAACTG
GCTGTTGTTCATGAATCTGAAGGATTGTTGGGGTACATTTACTGTGATTTTTTTCAGCGA
GCAGACAAACCACATCAGGATTGCCATTTCACTATCCGTGGAGGCAGACTAAAGGAAGAT
GGAGACTATCAACTCCCAGTTGTAGTTCTTATGCTGAATCTTCCCCGTTCCTCAAGGAGT
TCTCCAACTTTGCTAACTCCTGGCATGATGGAAAATCTTTTCCATGAAATGGGACATGCC
ATGCATTCAATGCTAGGACGTACTCGTTACCAACACGTCACTGGGACCAGGTGCCCTACT
GATTTTGCTGAGGTTCCTTCTATTCTGATGGAGTACTTTGCAAATGATTATCGAGTAGTT
AACCAATTTGCCAGACATTATCAGACTGGACAGCCACTGCCAAAAAATATGGTGTCTCGT
CTTTGTGAATCTAAAAAGGTTTGTGCTGCAGCTGATATGCAACTTCAGGTCTTTTATGCC
ACTCTGGATCAAATCTACCATGGGAAGCATCCCCTGAGGAATTCAACCACAGACATTCTC
AAGGAAACACAAGAGAAATTCTATGGCCTACCATATGTTCCAAATACTGCCTGGCAGCTG
CGATTCAGCCACCTCGTGGGGTATGGTGCTAGATATTACTCTTACCTCATGTCCAGAGCG
GTCGCCTCCATGGTTTGGAAGGAGTGTTTTCTACAGGATCCTTTCAACAGGGCTGCCGGG
GAGCGCTATCGCAGGGAGATGCTGGCCCACGGTGGAGGCAGGGAGCCCATGCTCATGGTT
GAAGGTATGCTTCAGAAGTGTCCTTCTGTTGATGACTTCGTAAGTGCCCTCGTTTCCGAC
TTGGATCTGGACTTCGAAACTTTCCTCATGGATTCTGAATAA
|
Protein Properties |
Number of Residues
| 713 |
Molecular Weight
| 80639.9 |
Theoretical pI
| 7.04 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Mitochondrial intermediate peptidase
MLCVGRLGGLGARAAALPPRRAGRGSLEAGIRARRVSTSWSPVGAAFNVKPQGSRLDLFG
ERRGLFGVPELSAPEGFHIAQEKALRKTELLVDRACSTPPGPQTVLIFDELSDSLCRVAD
LADFVKIAHPEPAFREAAEEACRSIGTMVEKLNTNVDLYQSLQKLLADKKLVDSLDPETR
RVAELFMFDFEISGIHLDKEKRKRAVDLNVKILDLSSTFLMGTNFPNKIEKHLLPEHIRR
NFTSAGDHIIIDGLHAESPDDLVREAAYKIFLYPNAGQLKCLEELLSSRDLLAKLVGYST
FSHRALQGTIAKNPETVMQFLEKLSDKLSERTLKDFEMIRGMKMKLNPQNSEVMPWDPPY
YSGVIRAERYNIEPSLYCPFFSLGACMEGLNILLNRLLGISLYAEQPAKGEVWSEDVRKL
AVVHESEGLLGYIYCDFFQRADKPHQDCHFTIRGGRLKEDGDYQLPVVVLMLNLPRSSRS
SPTLLTPSMMENLFHEMGHAMHSMLGRTRYQHVTGTRCPTDFAEVPSILMEYFANDYRVV
NQFARHYQTGQPLPKNMVSRLCESKKVCAAADMQLQVFYATLDQIYHGKHPLRNSTTDIL
KETQEKFYGLPYVPNTAWQLRFSHLVGYGARYYSYLMSRAVASMVWKECFLQDPFNRAAG
ERYRREMLAHGGGREPMLMVEGMLQKCPSVDDFVSALVSDLDLDFETFLMDSE
|
External Links |
GenBank ID Protein
| 158257278 |
UniProtKB/Swiss-Prot ID
| Q99797 |
UniProtKB/Swiss-Prot Entry Name
| MIPEP_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| AK291923 |
GeneCard ID
| MIPEP |
GenAtlas ID
| MIPEP |
HGNC ID
| HGNC:7104 |
References |
General References
| Not Available |