| Identification |
|---|
| HMDB Protein ID
| CDBP02997 |
| Secondary Accession Numbers
| Not Available |
| Name
| Vesicular integral-membrane protein VIP36 |
| Description
| Not Available |
| Synonyms
|
- Glycoprotein GP36b
- Lectin mannose-binding 2
|
| Gene Name
| LMAN2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in sugar binding |
| Specific Function
| Plays a role as an intracellular lectin in the early secretory pathway. Interacts with N-acetyl-D-galactosamine and high-mannose type glycans and may also bind to O-linked glycans. Involved in the transport and sorting of glycoproteins carrying high mannose-type glycans |
| GO Classification
|
| Component |
| membrane |
| cell part |
|
| Cellular Location
|
- Golgi apparatus membrane
- Endoplasmic reticulum membrane
- Single-pass type I membrane protein
- Single-pass type I membrane protein
- Single-pass membrane protein
- endoplasmic reticulum-Golgi intermediate compartment membrane
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:5 |
| Locus
| 5q35.3 |
| SNPs
| LMAN2 |
| Gene Sequence
|
>1071 bp
ATGGCGGCGGAAGGCTGGATTTGGCGTTGGGGCTGGGGCCGGCGGTGCCTGGGAAGGCCT
GGGCTTCTCGGCCCCGGCCCTGGCCCCACTACACCTCTCTTTCTTCTTTTGTTGTTGGGG
TCTGTGACTGCGGATATAACTGACGGCAACAGTGAACATCTCAAGCGGGAGCATTCGCTC
ATTAAGCCCTACCAAGGGGTCGGTTCCAGCTCTATGCCCCTCTGGGACTTCCAGGGCAGC
ACTATGCTCACGAGCCAGTACGTACGTCTGACCCCTGACGAGCGCAGCAAAGAGGGCTCT
ATCTGGAACCACCAGCCGTGCTTCCTCAAAGACTGGGAAATGCACGTCCACTTCAAAGTC
CACGGCACAGGGAAGAAGAACCTCCATGGAGACGGCATCGCCTTGTGGTACACCCGGGAC
CGCCTCGTGCCAGGGCCTGTGTTTGGAAGCAAAGATAACTTCCACGGCTTAGCCATCTTC
CTGGACACCTACCCCAATGATGAGACCACTGAGCGCGTGTTCCCGTACATCTCGGTGATG
GTGAACAATGGCTCCCTGTCCTACGACCACAGCAAGGATGGGCGCTGGACCGAGCTGGCG
GGCTGCACGGCTGACTTCCGCAACCGCGATCACGACACCTTCCTGGCTGTGCGCTACTCC
CGGGGCCGTCTGACGGTGATGACCGACCTGGAGGACAAGAACGAGTGGAAGAACTGCATT
GACATCACGGGAGTGCGCCTGCCCACCGGCTACTACTTCGGGGCCTCCGCCGGCACCGGC
GACCTGTCTGACAATCGTGACATCATCTCCATGAAGCTGTTCCAGCTGATGGTGGAGCAC
ACGCCCGACGAGGAGAGCATCGACTGGACCAAGATCGAGCCCAGCGTCAACTTCCTCAAG
TCGCCCAAAGACAACGTGGACGACCCCACGGGGAACTTCCGCAGCGGGCCCCTGACGGGG
TGGCGGGTGTTCCTGCTGCTGCTGTGCGCTCTCCTGGGCATCGTTGTCTGCGCCGTGGTG
GGGGCCGTGGTGTTCCAGAAGCGGCAGGAGCGGAACAAGCGCTTCTACTGA
|
| Protein Properties |
|---|
| Number of Residues
| 356 |
| Molecular Weight
| 40228.4 |
| Theoretical pI
| 6.95 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Vesicular integral-membrane protein VIP36
MAAEGWIWRWGWGRRCLGRPGLLGPGPGPTTPLFLLLLLGSVTADITDGNSEHLKREHSL
IKPYQGVGSSSMPLWDFQGSTMLTSQYVRLTPDERSKEGSIWNHQPCFLKDWEMHVHFKV
HGTGKKNLHGDGIALWYTRDRLVPGPVFGSKDNFHGLAIFLDTYPNDETTERVFPYISVM
VNNGSLSYDHSKDGRWTELAGCTADFRNRDHDTFLAVRYSRGRLTVMTDLEDKNEWKNCI
DITGVRLPTGYYFGASAGTGDLSDNHDIISMKLFQLMVEHTPDEESIDWTKIEPSVNFLK
SPKDNVDDPTGNFRSGPLTGWRVFLLLLCALLGIVVCAVVGAVVFQKRQERNKRFY
|
| External Links |
|---|
| GenBank ID Protein
| 62896777 |
| UniProtKB/Swiss-Prot ID
| Q12907 |
| UniProtKB/Swiss-Prot Entry Name
| LMAN2_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AK222609 |
| GeneCard ID
| LMAN2 |
| GenAtlas ID
| LMAN2 |
| HGNC ID
| HGNC:16986 |
| References |
|---|
| General References
| Not Available |