Showing Protein Phosphorylase b kinase regulatory subunit alpha, liver isoform (CDBP02981)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 compounds
Identification
HMDB Protein ID CDBP02981
Secondary Accession Numbers Not Available
Name Phosphorylase b kinase regulatory subunit alpha, liver isoform
Description Not Available
Synonyms
  1. Phosphorylase kinase alpha L subunit
Gene Name PHKA2
Protein Type Enzyme
Biological Properties
General Function Involved in catalytic activity
Specific Function Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin
GO Classification
Function
calmodulin binding
protein binding
glucan 1,4-alpha-glucosidase activity
glucosidase activity
binding
catalytic activity
hydrolase activity
hydrolase activity, acting on glycosyl bonds
hydrolase activity, hydrolyzing o-glycosyl compounds
Process
polysaccharide metabolic process
metabolic process
primary metabolic process
carbohydrate metabolic process
glycogen metabolic process
small molecule metabolic process
alcohol metabolic process
monosaccharide metabolic process
hexose metabolic process
glucose metabolic process
Cellular Location
  1. Cell membrane
  2. Lipid-anchor
  3. Cytoplasmic side (Potential)
Pathways
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs PHKA2
Gene Sequence 
>3708 bp
ATGCGGAGCAGGAGCAATTCCGGGGTCCGCTTGGACGGGTACGCGCGGCTGGTGCAGCAA
ACCATCCTGTGTTACCAGAATCCCGTCACGGGGCTGCTGTCAGCCAGCCATGAGCAGAAG
GATGCCTGGGTGCGGGATAACATCTACAGTATCCTGGCCGTGTGGGGCCTGGGCATGGCC
TACCGTAAGAATGCAGACCGCGATGAGGACAAGGCCAAGGCCTACGAGCTGGAGCAGAAC
GTGGTGAAGCTGATGCGAGGTCTTCTCCAGTGCATGATGAGACAGGTGGCCAAAGTGGAG
AAGTTCAAACACACTCAGAGCACCAAGGACAGCCTGCACGCCAAGTACAACACCGCCACC
TGTGGCACGGTGGTGGGCGACGACCAGTGGGGCCACCTCCAGGTGGATGCCACCTCTCTC
TTCCTCCTGTTCCTGGCCCAGATGACCGCCTCAGGCTTACGTATCATTTTCACTCTCGAT
GAGGTGGCCTTCATACAGAATCTTGTCTTTTACATAGAAGCTGCATATAAAGTCGCTGAT
TATGGAATGTGGGAGCGTGGAGATAAGACTAATCAGGGCATCCCGGAATTGAATGCAAGC
TCCGTAGGAATGGCCAAGGCAGCTCTTGAGGCAATTGATGAACTGGACCTTTTTGGAGCC
CATGGAGGACGCAAGTCAGTGATTCATGTTCTGCCAGATGAGGTCGAGCACTGCCAGTCT
ATTCTGTTCTCCATGCTGCCAAGAGCGTCGACATCTAAAGAAATTGATGCTGGACTTCTT
TCCATTATTTCCTTCCCGGCCTTTGCAGTGGAAGATGTAAACCTTGTAAATGTGACCAAA
AATGAAATTATTTCTAAGCTCCAGGGGCGTTATGGATGCTGTCGCTTCCTTCGAGATGGT
TATAAAACTCCAAGAGAGGACCCTAATCGACTGCATTATGACCCTGCTGAACTCAAGCTC
TTCGAAAACATTGAATGTGAGTGGCCTGTGTTTTGGACATATTTTATAATAGATGGAGTC
TTCAGTGGTGATGCTGTTCAGGTCCAAGAATACCGAGAGGCCCTGGAGGGAATACTCATC
AGAGGCAAGAATGGGATCCGCCTGGTGCCTGAACTCTACGCTGTCCCGCCTAACAAGGTA
GATGAAGAGTACAAGAATCCTCACACAGTAGACCGAGTTCCTATGGGGAAGGTGCCTCAT
CTGTGGGGCCAATCCTTGTACATCCTCAGCTCGCTGTTGGCAGAGGGATTCCTTGCCGCT
GGTGAAATCGATCCCTTAAATAGAAGATTTTCCACTTCAGTCAAACCTGATGTTGTAGTA
CAAGTTACTGTTTTGGCAGAAAACAATCACATTAAGGACTTATTGAGGAAACACGGGGTG
AACGTCCAGAGTATCGCGGACATTCATCCAATTCAAGTCCAGCCGGGCCGGATTCTTAGT
CACATATATGCCAAGCTTGGACGGAATAAGAATATGAATTTGAGTGGGCGACCGTATCGA
CATATTGGTGTCCTTGGAACCTCTAAACTATATGTGATTAGGAACCAAATCTTTACTTTT
ACACCCCAGTTCACCGACCAGCATCACTTCTACCTGGCCCTCGACAATGAGATGATCGTG
GAGATGCTAAGGATCGAGCTGGCCTACCTGTGCACCTGCTGGAGGATGACGGGCAGACCC
ACACTCACCTTCCCCATCAGTCGCACCATGCTCACAAATGATGGCTCAGACATTCATTCT
GCTGTGCTCTCCACAATTAGAAAACTAGAGGATGGATATTTTGGAGGAGCCAGAGTAAAA
TTAGGGAACCTTTCGGAATTTCTCACCACATCGTTCTACACATATCTGACTTTTCTGGAT
CCAGACTGTGATGAGAAGTTGTTTGACAATGCCAGCGAAGGGACTTTCAGTCCTGATAGT
GATTCAGATTTGGTAGGATATCTGGAAGACACCTGTAATCAAGAAAGCCAAGACGAACTT
GACCATTATATCAACCACCTTCTGCAAAGCACATCGTTGAGGTCCTATCTGCCTCCTCTT
TGTAAGAACACAGAAGACCGCCATGTCTTCAGTGCTATCCACTCCACGCGGGACATACTT
TCTGTGATGGCAAAAGCAAAGGGTTTGGAAGTTCCATTTGTTCCCATGACTTTGCCGACT
AAAGTTCTAAGTGCCCACCGTAAATCACTGAATCTTGTTGATTCTCCTCAGCCACTCCTA
GAAAAGGTTCCTGAAAGTGACTTTCAGTGGCCCAGAGATGACCATGGTGACGTGGACTGT
GAGAAGCTGGTTGAGCAGCTAAAAGATTGTTCGAACCTACAGGACCAAGCAGACATTCTG
TACATTCTTTATGTCATAAAGGGTCCCAGCTGGGACACAAATCTCTCTGGACAGCACGGG
GTCACCGTTCAAAACCTTCTTGGTGAGCTCTATGGGAAAGCCGGCTTGAACCAGGAGTGG
GGTCTGATTCGCTACATCTCAGGCCTTCTCAGGAAGAAAGTGGAGGTCCTGGCTGAGGCC
TGCACAGACCTGCTTTCGCACCAGAAGCAGCTCACCGTGGGCCTGCCGCCCGAGCCCCGG
GAGAAGATCATCTCTGCGCCCCTTCCCCCAGAGGAGCTCACAAAACTCATCTACGAGGCC
AGTGGGCAGGACATCAGCATTGCCGTCCTCACGCAGGAGATTGTGGTTTACCTGGCCATG
TATGTCAGGGCGCAGCCCAGCCTCTTTGTGGAGATGCTGAGACTCCGGATTGGACTGATC
ATTCAGGTGATGGCCACGGAGCTGGCACGGAGCCTGAACTGCTCAGGAGAAGAGGCTTCT
GAAAGTTTGATGAACCTCAGCCCTTTCGATATGAAAAATCTCCTGCACCATATTCTAAGT
GGGAAAGAGTTTGGCGTTGAAAGAAGTGTGCGCCCTATCCACTCCTCCACATCCAGCCCT
ACCATCTCCATCCACGAGGTGGGCCATACCGGAGTCACCAAAACTGAGAGGAGTGGCATT
AACAGACTGAGGAGTGAAATGAAACAGATGACTAGGCGGTTTAGTGCTGATGAACAGTTC
TTTTCTGTGGGCCAGGCCGCGTCCAGCAGTGCGCATTCCTCCAAGTCTGCGAGGTCCAGC
ACCCCATCCTCGCCCACTGGCACGTCATCCTCAGACTCGGGAGGACATCACATCGGCTGG
GGTGAGCGGCAGGGCCAGTGGCTGCGCAGGAGAAGGCTGGATGGGGCCATCAACAGGGTC
CCCGTGGGATTCTACCAGAGGGTGTGGAAGATCCTCCAGAAGTGCCACGGTCTCTCCATC
GATGGTTATGTCCTCCCATCCTCGACGACCCGAGAGATGACCCCGCATGAGATCAAGTTT
GCTGTCCATGTCGAATCGGTGCTGAACCGCGTGCCGCAGCCCGAGTACCGGCAGCTGCTG
GTGGAAGCCATCATGGTGCTGACGCTGCTCTCGGACACGGAGATGACCAGCATCGGGGGC
ATCATCCACGTGGACCAGATCGTGCAGATGGCCAGTCAGCTGTTCTTGCAGGACCAGGTG
TCAATTGGTGCCATGGACACCCTGGAGAAAGACCAAGCCACAGGAATCTGCCACTTCTTT
TATGACAGCGCTCCGAGTGGGGCTTATGGGACGATGACCTACCTAACAAGAGCAGTGGCT
TCTTATTTGCAGGAATTGTTGCCCAATTCGGGCTGCCAGATGCAATAG
Protein Properties
Number of Residues 1235
Molecular Weight 138406.8
Theoretical pI 6.41
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence 
>Phosphorylase b kinase regulatory subunit alpha, liver isoform
MRSRSNSGVRLDGYARLVQQTILCYQNPVTGLLSASHEQKDAWVRDNIYSILAVWGLGMA
YRKNADRDEDKAKAYELEQNVVKLMRGLLQCMMRQVAKVEKFKHTQSTKDSLHAKYNTAT
CGTVVGDDQWGHLQVDATSLFLLFLAQMTASGLRIIFTLDEVAFIQNLVFYIEAAYKVAD
YGMWERGDKTNQGIPELNASSVGMAKAALEAIDELDLFGAHGGRKSVIHVLPDEVEHCQS
ILFSMLPRASTSKEIDAGLLSIISFPAFAVEDVNLVNVTKNEIISKLQGRYGCCRFLRDG
YKTPREDPNRLHYDPAELKLFENIECEWPVFWTYFIIDGVFSGDAVQVQEYREALEGILI
RGKNGIRLVPELYAVPPNKVDEEYKNPHTVDRVPMGKVPHLWGQSLYILSSLLAEGFLAA
GEIDPLNRRFSTSVKPDVVVQVTVLAENNHIKDLLRKHGVNVQSIADIHPIQVQPGRILS
HIYAKLGRNKNMNLSGRPYRHIGVLGTSKLYVIRNQIFTFTPQFTDQHHFYLALDNEMIV
EMLRIELAYLCTCWRMTGRPTLTFPISRTMLTNDGSDIHSAVLSTIRKLEDGYFGGARVK
LGNLSEFLTTSFYTYLTFLDPDCDEKLFDNASEGTFSPDSDSDLVGYLEDTCNQESQDEL
DHYINHLLQSTSLRSYLPPLCKNTEDRHVFSAIHSTRDILSVMAKAKGLEVPFVPMTLPT
KVLSAHRKSLNLVDSPQPLLEKVPESDFQWPRDDHGDVDCEKLVEQLKDCSNLQDQADIL
YILYVIKGPSWDTNLSGQHGVTVQNLLGELYGKAGLNQEWGLIRYISGLLRKKVEVLAEA
CTDLLSHQKQLTVGLPPEPREKIISAPLPPEELTKLIYEASGQDISIAVLTQEIVVYLAM
YVRAQPSLFVEMLRLRIGLIIQVMATELARSLNCSGEEASESLMNLSPFDMKNLLHHILS
GKEFGVERSVRPIHSSTSSPTISIHEVGHTGVTKTERSGINRLRSEMKQMTRRFSADEQF
FSVGQAASSSAHSSKSARSSTPSSPTGTSSSDSGGHHIGWGERQGQWLRRRRLDGAINRV
PVGFYQRVWKILQKCHGLSIDGYVLPSSTTREMTPHEIKFAVHVESVLNRVPQPEYRQLL
VEAIMVLTLLSDTEMTSIGGIIHVDQIVQMASQLFLQDQVSIGAMDTLEKDQATGICHFF
YDSAPSGAYGTMTYLTRAVASYLQELLPNSGCQMQ
GenBank ID Protein 4903263
UniProtKB/Swiss-Prot ID P46019
UniProtKB/Swiss-Prot Entry Name KPB2_HUMAN
PDB IDs Not Available
GenBank Gene ID AF044572
GeneCard ID PHKA2
GenAtlas ID PHKA2
HGNC ID HGNC:8926
References
General References Not Available