Identification |
HMDB Protein ID
| CDBP02964 |
Secondary Accession Numbers
| Not Available |
Name
| Calcium/calmodulin-dependent protein kinase type 1B |
Description
| Not Available |
Synonyms
|
- CaM kinase I beta
- CaM kinase IB
- CaM-KI beta
- CaMKI-beta
- Pregnancy up-regulated non-ubiquitously-expressed CaM kinase
|
Gene Name
| PNCK |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in protein kinase activity |
Specific Function
| Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. In vitro phosphorylates CREB1 and SYN1/synapsin I. Phosphorylates and activates CAMK1 |
GO Classification
|
Function |
nucleoside binding |
purine nucleoside binding |
adenyl nucleotide binding |
adenyl ribonucleotide binding |
atp binding |
protein kinase activity |
protein serine/threonine kinase activity |
binding |
catalytic activity |
transferase activity |
transferase activity, transferring phosphorus-containing groups |
kinase activity |
Process |
phosphorus metabolic process |
phosphate metabolic process |
metabolic process |
cellular metabolic process |
protein amino acid phosphorylation |
phosphorylation |
|
Cellular Location
|
- Nucleus
- Cytoplasm
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Not Available |
Locus
| Not Available |
SNPs
| PNCK |
Gene Sequence
|
>1083 bp
ATGTGGAGGCGTGTATGCGGTGGCCTCGCTGGGAGGCGTCCGTCTGGGGACATGCTGCTG
CTGAAGAAACACACGGAGGACATCAGCAGCGTCTACGAGATCCGCGAGAGGCTCGGCTCG
GGTGCCTTCTCCGAGGTGGTGCTGGCCCAGGAGCGGGGCTCCGCACACCTCGTGGCCCTC
AAGTGCATCCCCAAGAAGGCCCTCCGGGGCAAGGAGGCCCTGGTGGAGAACGAGATCGCA
GTGCTCCGTAGGATCAGTCACCCCAACATCGTCGCTCTGGAGGATGTCCACGAGAGCCCT
TCCCACCTCTACCTGGCCATGGAACTGGTGACGGGTGGCGAGCTGTTTGACCGCATCATG
GAGCGCGGCTCCTACACAGAGAAGGATGCCAGCCATCTGGTGGGTCAGGTCCTTGGCGCC
GTCTCCTACCTGCACAGCCTGGGGATCGTGCACCGGGACCTCAAGCCCGAAAACCTCCTG
TATGCCACGCCCTTTGAGGACTCGAAGATCATGGTCTCTGACTTTGGACTCTCCAAAATC
CAGGCTGGGAACATGCTAGGCACCGCCTGTGGGACCCCTGGATATGTGGCCCCAGAGCTC
TTGGAGCAGAAACCCTACGGGAAGGCCGTAGATGTGTGGGCCCTGGGCGTCATCTCCTAC
ATCCTGCTGTGTGGGTACCCCCCCTTCTACGACGAGAGCGACCCTGAGCTCTTCAGCCAG
ATCCTGAGGGCCAGCTATGAGTTTGACTCTCCTTTCTGGGATGACATCTCAGAATCAGCC
AAAGACTTCATCCGGCACCTTCTGGAGCGAGACCCCCAGAAGAGGTTCACCTGCCAACAG
GCCTTGCGGCACCTTTGGATCTCTGGGGACACAGCCTTCGACAGGGACATCTTAGGCTCT
GTCAGTGAGCAGATCCGGAAGAACTTTGCTCGGACACACTGGAAGCGAGCCTTCAATGCC
ACCTCGTTCCTGCGCCACATCCGGAAGCTGGGGCAGATCCCAGAGGGCGAGGGGGCCTCT
GAGCAGGGCATGGCCCGCCACAGCCACTCAGGCCTCCGTGCTGGCCAGCCCCCCAAGTGG
TGA
|
Protein Properties |
Number of Residues
| 343 |
Molecular Weight
| 38499.5 |
Theoretical pI
| 6.75 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Calcium/calmodulin-dependent protein kinase type 1B
MLLLKKHTEDISSVYEIRERLGSGAFSEVVLAQERGSAHLVALKCIPKKALRGKEALVEN
EIAVLRRISHPNIVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQV
LGAVSYLHSLGIVHRDLKPENLLYATPFEDSKIMVSDFGLSKIQAGNMLGTACGTPGYVA
PELLEQKPYGKAVDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDIS
ESAKDFIRHLLERDPQKRFTCQQALRHLWISGDTAFDRDILGSVSEQIRKNFARTHWKRA
FNATSFLRHIRKLGQIPEGEGASEQGMARHSHSGLRAGQPPKW
|
External Links |
GenBank ID Protein
| 209364621 |
UniProtKB/Swiss-Prot ID
| Q6P2M8 |
UniProtKB/Swiss-Prot Entry Name
| KCC1B_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| Not Available |
GeneCard ID
| PNCK |
GenAtlas ID
| PNCK |
HGNC ID
| HGNC:13415 |
References |
General References
| Not Available |