Identification
HMDB Protein ID CDBP02964
Secondary Accession Numbers Not Available
Name Calcium/calmodulin-dependent protein kinase type 1B
Description Not Available
Synonyms
  1. CaM kinase I beta
  2. CaM kinase IB
  3. CaM-KI beta
  4. CaMKI-beta
  5. Pregnancy up-regulated non-ubiquitously-expressed CaM kinase
Gene Name PNCK
Protein Type Enzyme
Biological Properties
General Function Involved in protein kinase activity
Specific Function Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. In vitro phosphorylates CREB1 and SYN1/synapsin I. Phosphorylates and activates CAMK1
GO Classification
Function
nucleoside binding
purine nucleoside binding
adenyl nucleotide binding
adenyl ribonucleotide binding
atp binding
protein kinase activity
protein serine/threonine kinase activity
binding
catalytic activity
transferase activity
transferase activity, transferring phosphorus-containing groups
kinase activity
Process
phosphorus metabolic process
phosphate metabolic process
metabolic process
cellular metabolic process
protein amino acid phosphorylation
phosphorylation
Cellular Location
  1. Nucleus
  2. Cytoplasm
Pathways
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs PNCK
Gene Sequence
>1083 bp
ATGTGGAGGCGTGTATGCGGTGGCCTCGCTGGGAGGCGTCCGTCTGGGGACATGCTGCTG
CTGAAGAAACACACGGAGGACATCAGCAGCGTCTACGAGATCCGCGAGAGGCTCGGCTCG
GGTGCCTTCTCCGAGGTGGTGCTGGCCCAGGAGCGGGGCTCCGCACACCTCGTGGCCCTC
AAGTGCATCCCCAAGAAGGCCCTCCGGGGCAAGGAGGCCCTGGTGGAGAACGAGATCGCA
GTGCTCCGTAGGATCAGTCACCCCAACATCGTCGCTCTGGAGGATGTCCACGAGAGCCCT
TCCCACCTCTACCTGGCCATGGAACTGGTGACGGGTGGCGAGCTGTTTGACCGCATCATG
GAGCGCGGCTCCTACACAGAGAAGGATGCCAGCCATCTGGTGGGTCAGGTCCTTGGCGCC
GTCTCCTACCTGCACAGCCTGGGGATCGTGCACCGGGACCTCAAGCCCGAAAACCTCCTG
TATGCCACGCCCTTTGAGGACTCGAAGATCATGGTCTCTGACTTTGGACTCTCCAAAATC
CAGGCTGGGAACATGCTAGGCACCGCCTGTGGGACCCCTGGATATGTGGCCCCAGAGCTC
TTGGAGCAGAAACCCTACGGGAAGGCCGTAGATGTGTGGGCCCTGGGCGTCATCTCCTAC
ATCCTGCTGTGTGGGTACCCCCCCTTCTACGACGAGAGCGACCCTGAGCTCTTCAGCCAG
ATCCTGAGGGCCAGCTATGAGTTTGACTCTCCTTTCTGGGATGACATCTCAGAATCAGCC
AAAGACTTCATCCGGCACCTTCTGGAGCGAGACCCCCAGAAGAGGTTCACCTGCCAACAG
GCCTTGCGGCACCTTTGGATCTCTGGGGACACAGCCTTCGACAGGGACATCTTAGGCTCT
GTCAGTGAGCAGATCCGGAAGAACTTTGCTCGGACACACTGGAAGCGAGCCTTCAATGCC
ACCTCGTTCCTGCGCCACATCCGGAAGCTGGGGCAGATCCCAGAGGGCGAGGGGGCCTCT
GAGCAGGGCATGGCCCGCCACAGCCACTCAGGCCTCCGTGCTGGCCAGCCCCCCAAGTGG
TGA
Protein Properties
Number of Residues 343
Molecular Weight 38499.5
Theoretical pI 6.75
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>Calcium/calmodulin-dependent protein kinase type 1B
MLLLKKHTEDISSVYEIRERLGSGAFSEVVLAQERGSAHLVALKCIPKKALRGKEALVEN
EIAVLRRISHPNIVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQV
LGAVSYLHSLGIVHRDLKPENLLYATPFEDSKIMVSDFGLSKIQAGNMLGTACGTPGYVA
PELLEQKPYGKAVDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDIS
ESAKDFIRHLLERDPQKRFTCQQALRHLWISGDTAFDRDILGSVSEQIRKNFARTHWKRA
FNATSFLRHIRKLGQIPEGEGASEQGMARHSHSGLRAGQPPKW
GenBank ID Protein 209364621
UniProtKB/Swiss-Prot ID Q6P2M8
UniProtKB/Swiss-Prot Entry Name KCC1B_HUMAN
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID PNCK
GenAtlas ID PNCK
HGNC ID HGNC:13415
References
General References Not Available