Identification
HMDB Protein ID CDBP02899
Secondary Accession Numbers Not Available
Name Alpha-2-HS-glycoprotein
Description Not Available
Synonyms
  1. Alpha-2-HS-glycoprotein chain A
  2. Alpha-2-HS-glycoprotein chain B
  3. Alpha-2-Z-globulin
  4. Ba-alpha-2-glycoprotein
  5. Fetuin-A
Gene Name AHSG
Protein Type Enzyme
Biological Properties
General Function Involved in cysteine-type endopeptidase inhibitor activity
Specific Function Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions
GO Classification
Function
cysteine-type endopeptidase inhibitor activity
peptidase inhibitor activity
endopeptidase inhibitor activity
enzyme regulator activity
enzyme inhibitor activity
Cellular Location
  1. Secreted
Pathways
Gene Properties
Chromosome Location Chromosome:3
Locus 3q27
SNPs AHSG
Gene Sequence
>1104 bp
ATGAAGTCCCTCGTCCTGCTCCTTTGTCTTGCTCAGCTCTGGGGCTGCCACTCAGCCCCA
CATGGCCCAGGGCTGATTTATAGACAACCGAACTGCGATGATCCAGAAACTGAGGAAGCA
GCTCTGGTGGCTATAGACTACATCAATCAAAACCTTCCTTGGGGATACAAACACACCTTG
AACCAGATTGATGAAGTAAAGGTGTGGCCTCAGCAGCCCTCCGGAGAGCTGTTTGAGATT
GAAATAGACACCCTGGAAACCACCTGCCATGTGCTGGACCCCACCCCTGTGGCAAGATGC
AGCGTGAGGCAGCTGAAGGAGCATGCTGTCGAAGGAGACTGTGATTTCCAGCTGTTGAAA
CTAGATGGCAAGTTTTCCGTGGTATACGCAAAATGTGATTCCAGTCCAGACTCAGCCGAG
GACGTGCGCAAGGTGTGCCAAGACTGCCCCCTGCTGGCCCCGCTGAACGACACCAGGGTG
GTGCACGCCGCGAAAGCTGCCCTGGCCGCCTTCAACGCTCAGAACAACGGCTCCAATTTT
CAGCTGGAGGAAATTTCCCGGGCTCAGCTTGTGCCCCTCCCACCTTCTACCTATGTGGAG
TTTACAGTGTCTGGCACTGACTGTGTTGCTAAAGAGGCCACAGAGGCAGCCAAGTGTAAC
CTGCTGGCAGAAAAGCAATATGGCTTTTGTAAGGCAACACTCAGTGAGAAGCTTGGTGGG
GCAGAGGTTGCAGTGACCTGCACGGTGTTCCAAACACAGCCCGTGACCTCACAGCCCCAA
CCAGAAGGTGCCAATGAAGCAGTCCCCACCCCCGTGGTGGACCCAGATGCACCTCCGTCC
CCTCCACTTGGCGCACCTGGACTCCCTCCAGCTGGCTCACCCCCAGACTCCCATGTGTTA
CTGGCAGCTCCTCCAGGACACCAGTTGCACCGGGCGCACTACGACCTGCGCCACACCTTC
ATGGGTGTGGTCTCATTGGGGTCACCCTCAGGAGAAGTGTCGCACCCCCGGAAAACACGC
ACAGTGGTGCAGCCTAGTGTTGGTGCTGCTGCTGGGCCAGTGGTTCCTCCATGTCCGGGG
AGGATCAGACACTTCAAGGTCTAG
Protein Properties
Number of Residues 367
Molecular Weight 39324.3
Theoretical pI 5.52
Pfam Domain Function
Signals
  • ["1-18"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>Alpha-2-HS-glycoprotein
MKSLVLLLCLAQLWGCHSAPHGPGLIYRQPNCDDPETEEAALVAIDYINQNLPWGYKHTL
NQIDEVKVWPQQPSGELFEIEIDTLETTCHVLDPTPVARCSVRQLKEHAVEGDCDFQLLK
LDGKFSVVYAKCDSSPDSAEDVRKVCQDCPLLAPLNDTRVVHAAKAALAAFNAQNNGSNF
QLEEISRAQLVPLPPSTYVEFTVSGTDCVAKEATEAAKCNLLAEKQYGFCKATLSEKLGG
AEVAVTCTVFQTQPVTSQPQPEGANEAVPTPVVDPDAPPSPPLGAPGLPPAGSPPDSHVL
LAAPPGHQLHRAHYDLRHTFMGVVSLGSPSGEVSHPRKTRTVVQPSVGAAAGPVVPPCPG
RIRHFKV
GenBank ID Protein 7106502
UniProtKB/Swiss-Prot ID P02765
UniProtKB/Swiss-Prot Entry Name FETUA_HUMAN
PDB IDs Not Available
GenBank Gene ID AB038689
GeneCard ID AHSG
GenAtlas ID AHSG
HGNC ID HGNC:349
References
General References Not Available