Identification |
HMDB Protein ID
| CDBP02899 |
Secondary Accession Numbers
| Not Available |
Name
| Alpha-2-HS-glycoprotein |
Description
| Not Available |
Synonyms
|
- Alpha-2-HS-glycoprotein chain A
- Alpha-2-HS-glycoprotein chain B
- Alpha-2-Z-globulin
- Ba-alpha-2-glycoprotein
- Fetuin-A
|
Gene Name
| AHSG |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in cysteine-type endopeptidase inhibitor activity |
Specific Function
| Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions |
GO Classification
|
Function |
cysteine-type endopeptidase inhibitor activity |
peptidase inhibitor activity |
endopeptidase inhibitor activity |
enzyme regulator activity |
enzyme inhibitor activity |
|
Cellular Location
|
- Secreted
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:3 |
Locus
| 3q27 |
SNPs
| AHSG |
Gene Sequence
|
>1104 bp
ATGAAGTCCCTCGTCCTGCTCCTTTGTCTTGCTCAGCTCTGGGGCTGCCACTCAGCCCCA
CATGGCCCAGGGCTGATTTATAGACAACCGAACTGCGATGATCCAGAAACTGAGGAAGCA
GCTCTGGTGGCTATAGACTACATCAATCAAAACCTTCCTTGGGGATACAAACACACCTTG
AACCAGATTGATGAAGTAAAGGTGTGGCCTCAGCAGCCCTCCGGAGAGCTGTTTGAGATT
GAAATAGACACCCTGGAAACCACCTGCCATGTGCTGGACCCCACCCCTGTGGCAAGATGC
AGCGTGAGGCAGCTGAAGGAGCATGCTGTCGAAGGAGACTGTGATTTCCAGCTGTTGAAA
CTAGATGGCAAGTTTTCCGTGGTATACGCAAAATGTGATTCCAGTCCAGACTCAGCCGAG
GACGTGCGCAAGGTGTGCCAAGACTGCCCCCTGCTGGCCCCGCTGAACGACACCAGGGTG
GTGCACGCCGCGAAAGCTGCCCTGGCCGCCTTCAACGCTCAGAACAACGGCTCCAATTTT
CAGCTGGAGGAAATTTCCCGGGCTCAGCTTGTGCCCCTCCCACCTTCTACCTATGTGGAG
TTTACAGTGTCTGGCACTGACTGTGTTGCTAAAGAGGCCACAGAGGCAGCCAAGTGTAAC
CTGCTGGCAGAAAAGCAATATGGCTTTTGTAAGGCAACACTCAGTGAGAAGCTTGGTGGG
GCAGAGGTTGCAGTGACCTGCACGGTGTTCCAAACACAGCCCGTGACCTCACAGCCCCAA
CCAGAAGGTGCCAATGAAGCAGTCCCCACCCCCGTGGTGGACCCAGATGCACCTCCGTCC
CCTCCACTTGGCGCACCTGGACTCCCTCCAGCTGGCTCACCCCCAGACTCCCATGTGTTA
CTGGCAGCTCCTCCAGGACACCAGTTGCACCGGGCGCACTACGACCTGCGCCACACCTTC
ATGGGTGTGGTCTCATTGGGGTCACCCTCAGGAGAAGTGTCGCACCCCCGGAAAACACGC
ACAGTGGTGCAGCCTAGTGTTGGTGCTGCTGCTGGGCCAGTGGTTCCTCCATGTCCGGGG
AGGATCAGACACTTCAAGGTCTAG
|
Protein Properties |
Number of Residues
| 367 |
Molecular Weight
| 39324.3 |
Theoretical pI
| 5.52 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Alpha-2-HS-glycoprotein
MKSLVLLLCLAQLWGCHSAPHGPGLIYRQPNCDDPETEEAALVAIDYINQNLPWGYKHTL
NQIDEVKVWPQQPSGELFEIEIDTLETTCHVLDPTPVARCSVRQLKEHAVEGDCDFQLLK
LDGKFSVVYAKCDSSPDSAEDVRKVCQDCPLLAPLNDTRVVHAAKAALAAFNAQNNGSNF
QLEEISRAQLVPLPPSTYVEFTVSGTDCVAKEATEAAKCNLLAEKQYGFCKATLSEKLGG
AEVAVTCTVFQTQPVTSQPQPEGANEAVPTPVVDPDAPPSPPLGAPGLPPAGSPPDSHVL
LAAPPGHQLHRAHYDLRHTFMGVVSLGSPSGEVSHPRKTRTVVQPSVGAAAGPVVPPCPG
RIRHFKV
|
External Links |
GenBank ID Protein
| 7106502 |
UniProtKB/Swiss-Prot ID
| P02765 |
UniProtKB/Swiss-Prot Entry Name
| FETUA_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| AB038689 |
GeneCard ID
| AHSG |
GenAtlas ID
| AHSG |
HGNC ID
| HGNC:349 |
References |
General References
| Not Available |