Identification
HMDB Protein ID CDBP02888
Secondary Accession Numbers Not Available
Name Extended synaptotagmin-3
Description Not Available
Synonyms
  1. Chr3Syt
  2. E-Syt3
Gene Name ESYT3
Protein Type Enzyme
Biological Properties
General Function Not Available
Specific Function May play a role as calcium-regulated intrinsic membrane protein
GO Classification Not Available
Cellular Location
  1. Cell membrane
  2. Single-pass membrane protein
Pathways
Gene Properties
Chromosome Location Chromosome:3
Locus 3q22.3
SNPs ESYT3
Gene Sequence
>2661 bp
ATGCGAGCAGAGGAGCCCTGCGCCCCCGGGGCCCCCAGCGCCCTGGGAGCCCAGCGCACG
CCGGGCCCCGAGCTGCGCCTGTCCAGCCAGCTGCTGCCCGAGCTCTGTACCTTCGTGGTG
CGCGTGCTGTTCTACCTGGGGCCTGTCTACCTAGCTGGCTACCTGGGGCTCAGCATAACC
TGGTTGCTGCTCGGCGCCCTGCTGTGGATGTGGTGGCGCAGGAACCGCCGCGGGAAGCTT
GGGCGCCTGGCCGCCGCCTTCGAATTCCTTGACAATGAACGCGAGTTCATCAGCCGCGAG
CTGCGGGGCCAGCACCTGCCAGCCTGGATCCACTTCCCGGACGTGGAGCGGGTCGAGTGG
GCCAACAAGATCATCTCTCAGACCTGGCCCTACCTAAGCATGATCATGGAAAGCAAGTTC
CGGGAGAAACTTGAGCCCAAGATCCGAGAGAAGAGCATCCACCTGAGGACCTTTACCTTT
ACCAAGCTCTACTTTGGACAGAAGTGTCCCAGGGTCAACGGTGTCAAGGCACACACTAAT
ACGTGCAACCGAAGACGTGTGACTGTGGACCTGCAGATCTGCTACATCGGGGACTGTGAG
ATCAGTGTGGAGCTGCAGAAGATTCAGGCTGGTGTGAACGGGATCCAGTTGCAGGGCACC
CTGCGGGTCATCCTGGAGCCCCTCCTAGTGGACAAGCCCTTTGTGGGAGCCGTGACTGTG
TTCTTCCTTCAGAAGCCGCACCTACAGATCAACTGGACTGGCCTGACCAACCTGCTGGAT
GCGCCGGGAATCAATGATGTGTCAGACAGCTTACTGGAGGACCTCATTGCCACCCACCTG
GTGCTGCCCAACCGTGTGACTGTGCCTGTGAAGAAGGGGCTGGATCTGACCAACCTGCGC
TTCCCTCTGCCCTGTGGGGTGATCAGAGTGCACTTGCTGGAGGCAGAGCAGCTGGCCCAG
AAGGACAACTTTCTGGGGCTCCGAGGCAAGTCAGATCCCTACGCCAAGGTGAGCATCGGC
CTACAGCATTTCCGGAGTAGGACCATCTACAGGAACCTGAACCCCACCTGGAACGAAGTG
TTTGAGTTCATGGTGTACGAAGTCCCTGGACAGGACCTGGAGGTAGACCTGTATGATGAG
GATACCGACAGGGATGACTTCCTGGGCAGCCTGCAGATCTGCCTTGGAGATGTCATGACC
AACAGAGTGGTGGATGAGTGGTTTGTCCTGAATGACACAACCAGCGGGCGGCTGCACCTG
CGGCTGGAGTGGCTTTCATTGCTTACTGACCAAGAAGTTCTGACTGAGGACCATGGTGGC
CTTTCCACTGCCATTCTCGTGGTCTTCTTGGAGAGTGCCTGCAACTTGCCGAGAAACCCT
TTTGACTACCTGAATGGTGAATATCGAGCCAAAAAACTCTCCAGGTTTGCCAGAAACAAG
GTCAGCAAAGACCCTTCTTCCTATGTCAAACTATCTGTAGGCAAGAAGACACATACAAGT
AAGACCTGTCCCCACAACAAGGACCCTGTGTGGAGCCAGGTGTTCTCCTTCTTTGTGCAC
AATGTGGCCACTGAGCGGCTCCATCTGAAGGTGCTTGATGATGACCAGGAGTGTGCTCTG
GGAATGCTGGAGGTCCCCCTGTGCCAGATCCTCCCCTATGCTGACCTCACTCTTGAGCAG
CGCTTTCAGCTGGACCACTCAGGCCTGGACAGCCTCATCTCCATGAGGCTGGTGCTTCGG
TTCCTGCAAGTGGAGGAACGAGAGCTGGGGAGCCCATACACAGGACCTGAAGCCCTAAAG
AAAGGCCCTCTGCTCATCAAGAAAGTGGCTACCAACCAGGGTCCCAAAGCCCAACCTCAG
GAAGAAGGCCCTACAGATTTGCCATGTCCCCCAGACCCTGCTTCTGATACTAAGGACGTA
TCCAGGAGTACCACAACCACCACCAGTGCTACCACCGTTGCCACTGAGCCCACATCCCAA
GAGACAGGCCCAGAGCCTAAAGGCAAGGACAGTGCCAAAAGGTTCTGTGAGCCCATCGGG
GAGAAGAAGAGTCCAGCCACCATCTTCCTGACTGTCCCAGGTCCCCACTCTCCAGGGCCC
ATCAAGTCACCCAGACCCATGAAATGCCCTGCCTCCCCATTCGCATGGCCGCCCAAGAGG
CTGGCTCCCAGCATGTCCTCGCTCAACTCCTTGGCCTCTTCTTGCTTTGACCTGGCAGAT
ATCAGCCTCAACATTGAAGGTGGGGACCTCAGGCGACGGCAGCTGGGTGAGATTCAGCTC
ACAGTGCGCTATGTGTGTCTGCGGCGCTGCCTCAGCGTGCTAATCAATGGCTGCAGAAAC
CTAACACCATGTACCAGCAGTGGAGCTGATCCCTACGTCCGTGTCTACTTGTTGCCAGAA
AGGAAGTGGGCATGTCGTAAGAAGACTTCAGTGAAGCGGAAGACCTTGGAACCCCTGTTT
GATGAGACATTTGAATTTTTTGTTCCCATGGAAGAAGTAAAGAAGAGGTCACTAGATGTT
GCAGTGAAAAATAGTAGGCCACTTGGCTCACACAGAAGAAAGGAGTTAGGAAAAGTACTG
ATTGACTTATCAAAAGAAGATCTGATTAAGGGCTTTTCACAATGGTATGAGCTGACTCCA
AATGGACAGCCCAGAAGCTGA
Protein Properties
Number of Residues 886
Molecular Weight 100034.5
Theoretical pI 8.47
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["51-71"]
Protein Sequence
>Extended synaptotagmin-3
MRAEEPCAPGAPSALGAQRTPGPELRLSSQLLPELCTFVVRVLFYLGPVYLAGYLGLSIT
WLLLGALLWMWWRRNRRGKLGRLAAAFEFLDNEREFISRELRGQHLPAWIHFPDVERVEW
ANKIISQTWPYLSMIMESKFREKLEPKIREKSIHLRTFTFTKLYFGQKCPRVNGVKAHTN
TCNRRRVTVDLQICYIGDCEISVELQKIQAGVNGIQLQGTLRVILEPLLVDKPFVGAVTV
FFLQKPHLQINWTGLTNLLDAPGINDVSDSLLEDLIATHLVLPNRVTVPVKKGLDLTNLR
FPLPCGVIRVHLLEAEQLAQKDNFLGLRGKSDPYAKVSIGLQHFRSRTIYRNLNPTWNEV
FEFMVYEVPGQDLEVDLYDEDTDRDDFLGSLQICLGDVMTNRVVDEWFVLNDTTSGRLHL
RLEWLSLLTDQEVLTEDHGGLSTAILVVFLESACNLPRNPFDYLNGEYRAKKLSRFARNK
VSKDPSSYVKLSVGKKTHTSKTCPHNKDPVWSQVFSFFVHNVATERLHLKVLDDDQECAL
GMLEVPLCQILPYADLTLEQRFQLDHSGLDSLISMRLVLRFLQVEERELGSPYTGPEALK
KGPLLIKKVATNQGPKAQPQEEGPTDLPCPPDPASDTKDVSRSTTTTTSATTVATEPTSQ
ETGPEPKGKDSAKRFCEPIGEKKSPATIFLTVPGPHSPGPIKSPRPMKCPASPFAWPPKR
LAPSMSSLNSLASSCFDLADISLNIEGGDLRRRQLGEIQLTVRYVCLRRCLSVLINGCRN
LTPCTSSGADPYVRVYLLPERKWACRKKTSVKRKTLEPLFDETFEFFVPMEEVKKRSLDV
AVKNSRPLGSHRRKELGKVLIDLSKEDLIKGFSQWYELTPNGQPRS
GenBank ID Protein 103472031
UniProtKB/Swiss-Prot ID A0FGR9
UniProtKB/Swiss-Prot Entry Name ESYT3_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_031913.3
GeneCard ID ESYT3
GenAtlas ID ESYT3
HGNC ID HGNC:24295
References
General References Not Available