Identification
HMDB Protein ID CDBP02884
Secondary Accession Numbers Not Available
Name Ectonucleoside triphosphate diphosphohydrolase 7
Description Not Available
Synonyms
  1. Lysosomal apyrase-like protein 1
  2. NTPDase 7
Gene Name ENTPD7
Protein Type Enzyme
Biological Properties
General Function Involved in hydrolase activity
Specific Function Preferentially hydrolyzes nucleoside 5'-triphosphates. The order of activity with respect to possible substrates is UTP > GTP > CTP
GO Classification
Function
catalytic activity
hydrolase activity
Cellular Location
  1. Multi-pass membrane protein (Potential)
  2. Cytoplasmic vesicle membrane
Pathways
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs ENTPD7
Gene Sequence
>1815 bp
ATGGCTAGGATCAGTTTTTCCTACCTCTGCCCAGCCTCCTGGTACTTCACTGTGCCCACA
GTGAGTCCATTTCTCCGTCAGCGGGTGGCATTCCTGGGACTCTTCTTCATATCCTGTCTC
CTTTTACTTATGTTAATCATAGACTTTCGACATTGGAGTGCTTCATTACCACGAGATAGG
CAATACGAAAGGTATTTGGCTCGAGTAGGGGAGCTTGAAGCTACTGACACTGAAGACCCA
AATCTGAATTATGGACTTGTTGTTGACTGTGGCAGCAGTGGTTCCCGGATTTTTGTTTAT
TTCTGGCCAAGACATAATGGGAACCCCCATGACTTGCTGGACATCAAACAGATGAGAGAC
CGCAACAGCCAACCAGTGGTTAAAAAAATCAAGCCAGGAATCTCTGCAATGGCAGACACT
CCAGAACATGCCAGTGATTACCTTCGTCCTCTGCTGAGCTTTGCTGCTGCTCATGTGCCT
GTGAAGAAGCACAAGGAGACCCCTCTTTACATCCTCTGCACAGCAGGCATGAGGCTTCTC
CCTGAGAGGAAGCAGTTGGCTATCTTGGCTGACCTAGTGAAAGATTTACCCCTGGAGTTT
GACTTCCTCTTTTCACAGTCTCAAGCAGAAGTGATCTCTGGGAAGCAGGAAGGGGTTTAT
GCATGGATTGGAATCAACTTTGTTTTGGGAAGATTCGACCACGAGGATGAATCAGATGCT
GAGGCTACCCAGGAATTGGCAGCAGGACGGAGAAGGACAGTAGGGATACTGGATATGGGA
GGAGCCTCTCTCCAAATTGCTTATGAAGTTCCTACCTCAACCTCTGTCCTTCCTGCAAAG
CAGGAAGAAGCTGCCAAGATCCTGCTGGCTGAGTTCAACCTGGGCTGTGATGTGCAACAC
ACTGAACACGTGTACAGGGTTTATGTCACAACTTTTCTGGGTTTCGGAGGCAACTTTGCC
CGGCAGCGCTACGAAGACCTTGTTCTGAATGAAACTCTTAACAAAAACAGATTGCTTGGT
CAGAAGACAGGTCTGAGTCCCGACAATCCATTTCTGGATCCCTGCCTGCCAGTGGGACTC
ACAGATGTGGTGGAGAGGAACAGCCAAGTCTTACATGTCCGAGGAAGAGGAGACTGGGTG
TCTTGTGGGGCAATGCTGAGCCCCCTGCTGGCTCGCTCCAACACCAGCCAGGCCTCACTC
AATGGCATATATCAATCGCCTATTGACTTCAACAACAGCGAGTTCTACGGCTTCTCTGAG
TTTTTTTATTGTACAGAGGATGTGTTGCGCATTGGTGGCCGCTACCATGGGCCAACATTT
GCCAAGGCTGCTCAGGATTACTGTGGCATGGCTTGGTCGGTACTAACTCAGAGATTCAAG
AATGGCCTCTTTTCATCACATGCAGATGAGCATCGACTCAAATATCAGTGTTTTAAATCG
GCTTGGATGTACCAAGTCTTACATGAAGGATTCCACTTTCCCTATGACTACCCAAACCTG
CGGACAGCCCAGCTGGTGTATGACCGAGAGGTTCAGTGGACGCTGGGAGCCATTCTATAT
AAAACACGATTCTTACCACTCAGGGATCTTCGGCAGGAAGGTGTCCGACAAGCCCATGGT
AGCTGGTTCCGTCTCTCCTTTGTATACAACCACTATCTCTTCTTTGCCTGTATCCTGGTG
GTGCTACTGGCCATCTTCCTATACCTTCTGCGGCTACGCCGAATTCACCACCGACAAACA
CGAGCCTCAGCTCCATTGGACTTGCTGTGGCTTGAAGAGGTGGTGCCCATGATGGGAGTA
CAGGTGGGGCCGTGA
Protein Properties
Number of Residues 604
Molecular Weight 68959.5
Theoretical pI 7.6
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["29-49", "547-567"]
Protein Sequence
>Ectonucleoside triphosphate diphosphohydrolase 7
MARISFSYLCPASWYFTVPTVSPFLRQRVAFLGLFFISCLLLLMLIIDFRHWSASLPRDR
QYERYLARVGELEATDTEDPNLNYGLVVDCGSSGSRIFVYFWPRHNGNPHDLLDIKQMRD
RNSQPVVKKIKPGISAMADTPEHASDYLRPLLSFAAAHVPVKKHKETPLYILCTAGMRLL
PERKQLAILADLVKDLPLEFDFLFSQSQAEVISGKQEGVYAWIGINFVLGRFDHEDESDA
EATQELAAGRRRTVGILDMGGASLQIAYEVPTSTSVLPAKQEEAAKILLAEFNLGCDVQH
TEHVYRVYVTTFLGFGGNFARQRYEDLVLNETLNKNRLLGQKTGLSPDNPFLDPCLPVGL
TDVVERNSQVLHVRGRGDWVSCGAMLSPLLARSNTSQASLNGIYQSPIDFNNSEFYGFSE
FFYCTEDVLRIGGRYHGPTFAKAAQDYCGMAWSVLTQRFKNGLFSSHADEHRLKYQCFKS
AWMYQVLHEGFHFPYDYPNLRTAQLVYDREVQWTLGAILYKTRFLPLRDLRQEGVRQAHG
SWFRLSFVYNHYLFFACILVVLLAIFLYLLRLRRIHHRQTRASAPLDLLWLEEVVPMMGV
QVGP
GenBank ID Protein 9623384
UniProtKB/Swiss-Prot ID Q9NQZ7
UniProtKB/Swiss-Prot Entry Name ENTP7_HUMAN
PDB IDs Not Available
GenBank Gene ID AF269255
GeneCard ID ENTPD7
GenAtlas ID ENTPD7
HGNC ID HGNC:19745
References
General References Not Available