| Identification |
|---|
| HMDB Protein ID
| CDBP02877 |
| Secondary Accession Numbers
| Not Available |
| Name
| Dentin sialophosphoprotein |
| Description
| Not Available |
| Synonyms
|
- DPP
- DSP
- Dentin phosphophoryn
- Dentin phosphoprotein
- Dentin sialoprotein
|
| Gene Name
| DSPP |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Replication, recombination and repair |
| Specific Function
| DSP may be an important factor in dentinogenesis. DPP may bind high amount of calcium and facilitate initial mineralization of dentin matrix collagen as well as regulate the size and shape of the crystals |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Secreted
- extracellular space
- extracellular matrix
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:4 |
| Locus
| 4q21.3 |
| SNPs
| DSPP |
| Gene Sequence
|
>3906 bp
ATGAAGATAATTACATATTTTTGCATTTGGGCAGTAGCATGGGCCATTCCAGTTCCTCAA
AGCAAACCACTGGAGAGACATGTCGAAAAATCCATGAATTTGCATCTCCTAGCAAGATCA
AATGTGTCAGTACAGGATGAGTTAAATGCCAGTGGAACCATCAAAGAAAGTGGTGTCCTG
GTGCATGAAGGTGATAGAGGAAGGCAAGAGAATACCCAAGATGGTCACAAGGGAGAAGGG
AATGGCTCTAAGTGGGCAGAAGTAGGAGGGAAGAGTTTTTCTACATATTCCACATTAGCA
AACGAAGAGGGGAATATTGAGGGCTGGAATGGGGACACAGGAAAAGCAGAAACATATGGT
CATGATGGAATACATGGGAAAGAAGAAAACATCACAGCAAATGGCATCCAGGGACAAGTA
AGCATCATTGACAATGCTGGAGCCACAAACAGAAGCAACACTAATGGAAATACTGATAAG
AATACCCAAAATGGGGATGTTGGCGATGCAGGTCACAATGAGGATGTCGCTGTTGTCCAA
GAAGATGGACCTCAAGTAGCTGGAAGCAATAACAGTACAGACAATGAGGATGAAATAATT
GAGAATTCCTGTAGAAACGAGGGTAATACAAGTGAAATAACACCTCAGATCAACAGCAAG
AGAAATGGGACTAAGGAAGCTGAGGTAACACCAGGCACTGGAGAAGATGCTGGCCTGGAT
AATTCCGATGGGAGTCCTAGTGGGAATGGAGCAGATGAGGATGAAGACGAGGGTTCTGGT
GATGATGAAGATGAAGAAGCAGGGAATGGAAAAGACAGTAGTAATAACAGCAAGGGCCAG
GAGGGCCAGGACCATGGGAAAGAAGATGATCATGATAGTAGCATAGGTCAAAATTCAGAT
AGTAAAGAATATTATGACCCTGAAGGCAAAGAAGATCCCCATAATGAAGTTGATGGAGAC
AAGACCTCCAAGAGTGAGGAGAATTCTGCTGGTATTCCAGAAGACAATGGCAGCCAAAGA
ATAGAGGACACCCAGAAGCTCAACCATAGAGAAAGCAAACGCGTAGAAAATAGAATCACC
AAAGAATCAGAGACACATGCTGTTGGGAAGAGCCAAGATAAGGGAATAGAAATCAAGGGT
CCCAGCAGTGGCAACAGAAATATTACCAAAGAAGTTGGGAAAGGCAACGAAGGTAAAGAG
GATAAAGGACAACATGGAATGATCTTGGGCAAAGGCAATGTCAAGACACAAGGAGAGGTT
GTCAACATAGAAGGACCTGGCCAAAAATCAGAACCAGGAAATAAAGTTGGACACAGCAAT
ACAGGTAGTGACAGCAATAGTGATGGATATGACAGTTATGATTTTGATGATAAGTCCATG
CAAGGAGATGATCCCAATAGCAGTGATGAATCTAATGGCAATGATGATGCTAATTCAGAA
AGTGACAATAACAGCAGTAGCCGAGGAGATGCTTCTTATAACTCTGATGAATCAAAAGAT
AATGGCAATGGCAGTGACTCAAAAGGAGCAGAAGATGATGACAGTGATAGCACATCAGAC
ACTAATAATAGTGACAGTAATGGCAATGGTAACAATGGGAATGATGACAATGACAAATCA
GACAGTGGCAAAGGTAAATCAGATAGCAGTGACAGTGATAGTAGTGATAGCAGCAATAGC
AGTGATAGTAGTGACAGCAGTGACAGTGACAGCAGTGATAGCAACAGTAGCAGTGATAGT
GACAGCAGTGACAGTGACAGCAGTGATAGCAGTGACAGTGATAGTAGTGATAGCAGCAAT
AGCAGTGACAGTAGTGACAGCAGTGATAGCAGTGACAGTAGTGATAGTAGTGACAGCAGT
GACAGCAAGTCAGACAGCAGCAAATCAGAGAGCGACAGCAGTGATAGTGACAGTAAGTCA
GACAGCAGTGACAGCAACAGCAGTGACAGTAGTGACAACAGTGATAGCAGCGACAGCAGC
AATAGCAGTAACAGCAGTGATAGTAGTGACAGCAGTGATAGCAGTGACAGCAGCAGTAGC
AGTGACAGCAGCAACAGCAGTGATAGTAGTGACAGTAGTGACAGCAGCAATAGCAGTGAG
AGCAGTGATAGTAGTGACAGCAGTGATAGTGACAGCAGTGATAGTAGTGACAGCAGTAAT
AGTAACAGCAGCGATAGTGACAGCAGCAACAGCAGCGATAGCAGTGACAGCAGCAACAGC
AGTGACAGCAGTGATAGCAGTGACAGCAGCAACAGCAGTGACAGTAGCGATAGCAGTGAC
AGCAGCAACAGCAGTGACAGCAGTGATAGCAGTGACAGCAGTGATAGTAGTGACAGCAGC
AACAGCAGTGATAGCAACGACAGCAGCAATAGCAGTGACAGCAGTGATAGCAGCAACAGC
AGTGATAGCAGCAACAGCAGTGATAGCAGTGATAGCAGTGACAGCAGTGATAGCGACAGC
AGCAATAGCAGTGACAGCAGTAATAGTAGTGACAGCAGCGATAGCAGCAACAGCAGTGAT
AGCAGCGACAGCAGCGATAGCAGTGACGGCAGTGATAGCGACAGCAGCAATAGAAGTGAC
AGTAGTAATAGTAGTGACAGCAGCGATAGCAGTGACAGCAGCAACAGCAGTGACAGCAGT
GATAGCAGTGACAGCAACGAAAGCAGCAATAGCAGTGACAGCAGTGATAGCAGCAACAGC
AGTGATAGTGACAGCAGTGATAGCAGCAACAGCAGTGACAGCAGTGATAGCAGCAACAGC
AGTGATAGCAGTGAAAGCAGTAATAGTAGTGACAACAGCAATAGCAGTGACAGCAGCAAC
AGCAGTGACAGCAGTGATAGCAGTGACAGCAGTAATAGTAGTGACAGCAGCAATAGCAGT
GACAGCAGCAACAGCAGTGACAGCAGTGATAGCAATAGCAGCGACAGCAGTGACAGCAGC
AACAGCAGCGATAGCAGTGACAGCAGTGATAGCAGTGACAGCAGTGACAGCAGTGATAGC
AGCAACAGCAGTGATAGCAGTGACAGCAGTGACAGCAGTGATAGCAGTAATAGTAGTGAC
AGCAGCAATAGCAGTGACAGCAGCAACAGCAGTGACAGCAGCGATAGCAGTGACAGCAGC
GATAGCAGTGACAGCAGCGATAGCAGTGACAGCAGTGACAGCAGCAATAGCAGTGACAGC
AGTGACAGCAGCGACAGCAGTGATAGCAGTGACAGCAGTGACAGCAGCGACAGCAGTGAT
AGCAGTGAAAGCAGTGATAGCAGTGACAGCAGCAATAGCAGTGACAGCAGCGATAGCAGC
GACAGCAGCGACAGCAGCGATAGCAGTGACAGCAGCGATAGCAGTGACAGCAGTGACAGC
AGCAATAGCAGTGACAGCAGTGACAGCAGCGACAGCAGTGATAGCAGTGACAGCAGCAAC
AGCAGTGACAGCAGTGACAGCAGTGAAAGCAGCGACAGCAGTGACAGCAGCGACAGCAGT
GACAGCAGCGATAGCAGCGACAGCAGCGACAGCAGCGATAGCAGTGACAGCAGCAATAGC
AGTGATAGCAGCGACAGCAGTGATAGCAGTGACAGCAGCGACAGCAGCGATAGCAGCGAC
AGCAGCGATAGTAGTGATAGCAGTGACAGCAGTGACAGCAGCGACAGCAGTGACAGCAGC
GACAGCAGTGACAGCAGCGACAGCAGTGACAGCAATGAAAGCAGCGACAGCAGTGACAGC
AGCGATAGCAGTGACAGCAGCAACAGCAGTGACAGCAGCGACAGCAGTGATAGCAGTGAC
AGCACATCTGACAGCAATGATGAGAGTGACAGCCAGAGCAAGTCTGGTAACGGTAACAAC
AATGGAAGTGACAGTGACAGTGACAGTGAAGGCAGTGACAGTAACCACTCAACCAGTGAT
GATTAG
|
| Protein Properties |
|---|
| Number of Residues
| 1301 |
| Molecular Weight
| 131148.6 |
| Theoretical pI
| 3.4 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Dentin sialophosphoprotein
MKIITYFCIWAVAWAIPVPQSKPLERHVEKSMNLHLLARSNVSVQDELNASGTIKESGVL
VHEGDRGRQENTQDGHKGEGNGSKWAEVGGKSFSTYSTLANEEGNIEGWNGDTGKAETYG
HDGIHGKEENITANGIQGQVSIIDNAGATNRSNTNGNTDKNTQNGDVGDAGHNEDVAVVQ
EDGPQVAGSNNSTDNEDEIIENSCRNEGNTSEITPQINSKRNGTKEAEVTPGTGEDAGLD
NSDGSPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQNSD
SKEYYDPEGKEDPHNEVDGDKTSKSEENSAGIPEDNGSQRIEDTQKLNHRESKRVENRIT
KESETHAVGKSQDKGIEIKGPSSGNRNITKEVGKGNEGKEDKGQHGMILGKGNVKTQGEV
VNIEGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSE
SDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKS
DSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSN
SSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSS
NSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSN
SNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSS
NSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSD
SSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNS
SDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSS
DSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSD
SSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD
SSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN
SSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSD
SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSD
STSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSDD
|
| External Links |
|---|
| GenBank ID Protein
| 89001107 |
| UniProtKB/Swiss-Prot ID
| Q9NZW4 |
| UniProtKB/Swiss-Prot Entry Name
| DSPP_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_014208.3 |
| GeneCard ID
| DSPP |
| GenAtlas ID
| DSPP |
| HGNC ID
| HGNC:3054 |
| References |
|---|
| General References
| Not Available |