Identification |
HMDB Protein ID
| CDBP02860 |
Secondary Accession Numbers
| Not Available |
Name
| C-X-C motif chemokine 13 |
Description
| Not Available |
Synonyms
|
- Angie
- B cell-attracting chemokine 1
- B lymphocyte chemoattractant
- BCA-1
- CXC chemokine BLC
- Small-inducible cytokine B13
|
Gene Name
| CXCL13 |
Protein Type
| Receptor |
Biological Properties |
General Function
| Involved in cytokine activity |
Specific Function
| Chemotactic for B-lymphocytes but not for T-lymphocytes, monocytes and neutrophils. Does not induce calcium release in B- lymphocytes. Binds to BLR1/CXCR5 |
GO Classification
|
Component |
extracellular region |
Function |
cytokine activity |
chemokine activity |
binding |
protein binding |
receptor binding |
Process |
immune system process |
immune response |
|
Cellular Location
|
- Secreted
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:4 |
Locus
| 4q21 |
SNPs
| CXCL13 |
Gene Sequence
|
>330 bp
ATGAAGTTCATCTCGACATCTCTGCTTCTCATGCTGCTGGTCAGCAGCCTCTCTCCAGTC
CAAGGTGTTCTGGAGGTCTATTACACAAGCTTGAGGTGTAGATGTGTCCAAGAGAGCTCA
GTCTTTATCCCTAGACGCTTCATTGATCGAATTCAAATCTTGCCCCGTGGGAATGGTTGT
CCAAGAAAAGAAATCATAGTCTGGAAGAAGAACAAGTCAATTGTGTGTGTGGACCCTCAA
GCTGAATGGATACAAAGAATGATGGAAGTATTGAGAAAAAGAAGTTCTTCAACTCTACCA
GTTCCAGTGTTTAAGAGAAAGATTCCCTGA
|
Protein Properties |
Number of Residues
| 109 |
Molecular Weight
| 12664.1 |
Theoretical pI
| 11.0 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>C-X-C motif chemokine 13
MKFISTSLLLMLLVSSLSPVQGVLEVYYTSLRCRCVQESSVFIPRRFIDRIQILPRGNGC
PRKEIIVWKKNKSIVCVDPQAEWIQRMMEVLRKRSSSTLPVPVFKRKIP
|
External Links |
GenBank ID Protein
| 3169814 |
UniProtKB/Swiss-Prot ID
| O43927 |
UniProtKB/Swiss-Prot Entry Name
| CXL13_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| AF029894 |
GeneCard ID
| CXCL13 |
GenAtlas ID
| CXCL13 |
HGNC ID
| HGNC:10639 |
References |
General References
| Not Available |