Identification
HMDB Protein ID CDBP02843
Secondary Accession Numbers Not Available
Name Calpain small subunit 1
Description Not Available
Synonyms
  1. CANP small subunit
  2. CDPS
  3. CSS1
  4. Calcium-activated neutral proteinase small subunit
  5. Calcium-dependent protease small subunit
  6. Calcium-dependent protease small subunit 1
  7. Calpain regulatory subunit
Gene Name CAPNS1
Protein Type Metal Binding
Biological Properties
General Function Involved in calcium ion binding
Specific Function Regulatory subunit of the calcium-regulated non- lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction
GO Classification
Function
calcium ion binding
ion binding
cation binding
metal ion binding
binding
Cellular Location
  1. Cell membrane
  2. Cytoplasm
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 19q13.12
SNPs CAPNS1
Gene Sequence
>807 bp
ATGTTCCTGGTTAACTCGTTCTTGAAGGGCGGCGGCGGCGGCGGCGGGGGAGGCGGGGGC
CTGGGTGGGGGCCTGGGAAATGTGCTTGGAGGCCTGATCAGCGGGGCCGGGGGCGGCGGC
GGCGGCGGCGGCGGCGGCGGCGGTGGTGGAGGCGGCGGTGGCGGTGGAACGGCCATGCGC
ATCCTAGGCGGAGTCATCAGCGCCATCAGCGAGGCGGCTGCGCAGTACAACCCGGAGCCC
CCGCCCCCACGCACACATTACTCCAACATTGAGGCCAACGAGAGTGAGGAGGTCCGGCAG
TTCCGGAGACTCTTTGCCCAGCTGGCTGGAGATGACATGGAGGTCAGCGCCACAGAACTC
ATGAACATTCTCAATAAGGTTGTGACACGACACCCTGATCTGAAGACTGATGGTTTTGGC
ATTGACACATGTCGCAGCATGGTGGCCGTGATGGATAGCGACACCACAGGCAAGCTGGGC
TTTGAGGAATTCAAGTACTTGTGGAACAACATCAAAAGGTGGCAGGCCATATACAAACAG
TTCGACACTGACCGATCAGGGACCATTTGCAGTAGTGAACTCCCAGGTGCCTTTGAGGCA
GCAGGGTTCCACCTGAATGAGCATCTCTATAACATGATCATCCGACGCTACTCAGATGAA
AGTGGGAACATGGATTTTGACAACTTCATCAGCTGCTTGGTCAGGCTGGACGCCATGTTC
CGTGCCTTCAAATCTCTTGACAAAGATGGCACTGGACAAATCCAGGTGAACATCCAGGAG
TGGCTGCAGCTGACTATGTATTCCTGA
Protein Properties
Number of Residues 268
Molecular Weight 28315.6
Theoretical pI 4.82
Pfam Domain Function Not Available
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>Calpain small subunit 1
MFLVNSFLKGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMR
ILGGVISAISEAAAQYNPEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATEL
MNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQ
FDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMF
RAFKSLDKDGTGQIQVNIQEWLQLTMYS
GenBank ID Protein 35328
UniProtKB/Swiss-Prot ID P04632
UniProtKB/Swiss-Prot Entry Name CPNS1_HUMAN
PDB IDs
GenBank Gene ID X04106
GeneCard ID CAPNS1
GenAtlas ID CAPNS1
HGNC ID HGNC:1481
References
General References Not Available