Identification
HMDB Protein ID CDBP02805
Secondary Accession Numbers Not Available
Name C-type lectin domain family 4 member K
Description Not Available
Synonyms
  1. CD207 antigen
  2. Langerin
Gene Name CD207
Protein Type Enzyme
Biological Properties
General Function Involved in binding
Specific Function Calcium-dependent lectin displaying mannose-binding specificity, Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering
GO Classification
Function
binding
Cellular Location
  1. Membrane
  2. Single-pass type II membrane protein
Pathways
Gene Properties
Chromosome Location Chromosome:2
Locus 2p13
SNPs CD207
Gene Sequence
>987 bp
ATGACTGTGGAGAAGGAGGCCCCTGATGCGCACTTCACTGTGGACAAACAGAACATCTCC
CTCTGGCCCCGAGAGCCTCCTCCCAAGTCCGGTCCATCTCTGGTCCCGGGGAAAACACCC
ACAGTCCGTGCTGCATTAATCTGCCTGACGCTGGTCCTGGTCGCCTCCGTCCTGCTGCAG
GCCGTCCTTTATCCCCGGTTTATGGGCACCATATCAGATGTAAAGACCAATGTCCAGTTG
CTGAAAGGTCGTGTGGACAACATCAGCACCCTGGATTCTGAAATTAAAAAGAATAGTGAC
GGCATGGAGGCAGCTGGCGTTCAGATCCAGATGGTGAATGAGAGCCTGGGTTATGTGCGT
TCTCAGTTCCTGAAGTTAAAAACCAGTGTGGAGAAGGCCAACGCACAGATCCAGATCTTA
ACAAGAAGTTGGGAAGAAGTCAGTACCTTAAATGCCCAAATCCCAGAGTTAAAAAGTGAT
TTGGAGAAAGCCAGTGCTTTAAATACAAAGATCCGGGCACTCCAGGGCAGCTTGGAGAAT
ATGAGCAAGTTGCTCAAACGACAAAATGATATTCTACAGGTGGTTTCTCAAGGCTGGAAG
TACTTCAAGGGGAACTTCTATTACTTTTCTCTCATTCCAAAGACCTGGTATAGTGCCGAG
CAGTTCTGTGTGTCCAGGAATTCACACCTGACCTCGGTGACCTCAGAGAGTGAGCAGGAG
TTTCTGTATAAAACAGCGGGGGGACTCATCTACTGGATTGGCCTGACTAAAGCAGGGATG
GAAGGGGACTGGTCCTGGGTGGATGACACGCCATTCAACAAGGTCCAAAGTGCGAGGTTC
TGGATTCCAGGTGAGCCCAACAATGCTGGGAACAATGAACACTGTGGCAATATAAAGGCT
CCCTCACTTCAGGCCTGGAATGATGCCCCATGTGACAAAACGTTTCTTTTCATTTGTAAG
CGACCCTATGTCCCATCAGAACCGTGA
Protein Properties
Number of Residues 328
Molecular Weight 36724.8
Theoretical pI 8.44
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["44-64"]
Protein Sequence
>C-type lectin domain family 4 member K
MTVEKEAPDAHFTVDKQNISLWPREPPPKSGPSLVPGKTPTVRAALICLTLVLVASVLLQ
AVLYPRFMGTISDVKTNVQLLKGRVDNISTLDSEIKKNSDGMEAAGVQIQMVNESLGYVR
SQFLKLKTSVEKANAQIQILTRSWEEVSTLNAQIPELKSDLEKASALNTKIRALQGSLEN
MSKLLKRQNDILQVVSQGWKYFKGNFYYFSLIPKTWYSAEQFCVSRNSHLTSVTSESEQE
FLYKTAGGLIYWIGLTKAGMEGDWSWVDDTPFNKVQSVRFWIPGEPNNAGNNEHCGNIKA
PSLQAWNDAPCDKTFLFICKRPYVPSEP
GenBank ID Protein 305410858
UniProtKB/Swiss-Prot ID Q9UJ71
UniProtKB/Swiss-Prot Entry Name CLC4K_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_015717.3
GeneCard ID CD207
GenAtlas ID CD207
HGNC ID HGNC:17935
References
General References Not Available