Identification
HMDB Protein ID CDBP02802
Secondary Accession Numbers Not Available
Name C-type lectin domain family 10 member A
Description Not Available
Synonyms
  1. C-type lectin superfamily member 14
  2. CD301 antigen
  3. Macrophage lectin 2
Gene Name CLEC10A
Protein Type Enzyme
Biological Properties
General Function Involved in sugar binding
Specific Function Probable role in regulating adaptive and innate immune responses. Binds in a calcium-dependent manner to terminal galactose and N-acetylgalactosamine units, linked to serine or threonine. These sugar moieties are known as Tn-Ag and are expressed in a variety of carcinoma cells
GO Classification
Component
membrane
cell part
Function
binding
carbohydrate binding
sugar binding
Cellular Location
  1. Membrane
  2. Single-pass type II membrane protein (Probable)
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 17p13.1
SNPs CLEC10A
Gene Sequence
>951 bp
ATGACAAGGACGTATGAAAACTTCCAGTACTTGGAGAATAAGGTGAAAGTCCAGGGGTTT
AAAAATGGGCCACTTCCTCTCCAGTCCCTCCTGCAGCGTCTCTGCTCTGGGCCCTGCCAT
CTCCTGCTGTCCCTGGGCCTCGGCCTCCTGCTGCTGGTCATCATCTGTGTGGTTGGATTC
CAAAATTCCAAATTTCAGAGGGACCTGGTGACCCTGAGAACAGATTTTAGCAACTTCACC
TCAAACACTGTGGCGGAGATCCAGGCACTGACTTCCCAGGGCAGCAGCTTGGAAGAAACG
ATAGCATCTCTGAAAGCTGAGGTGGAGGGTTTCAAGCAGGAACGGCAGGCAGGGGTATCT
GAGCTCCAGGAACACACTACGCAGAAGGCACACCTAGGCCACTGTCCCCACTGCCCATCT
GTGTGTGTCCCAGTTCATTCTGAAATGCTCCTGCGAGTCCAGCAGCTGGTGCAAGACCTG
AAGAAACTGACCTGCCAGGTGGCTACTCTCAACAACAATGCCTCCACTGAAGGGACCTGC
TGCCCTGTCAACTGGGTGGAGCACCAAGACAGCTGCTACTGGTTCTCTCACTCTGGGATG
TCCTGGGCCGAGGCTGAGAAGTACTGCCAGCTGAAGAACGCCCACCTGGTGGTCATCAAC
TCCAGGGAGGAGCAGAATTTTGTCCAGAAATATCTAGGCTCCGCATACACCTGGATGGGC
CTCAGTGACCCTGAAGGAGCCTGGAAGTGGGTGGATGGAACAGACTATGCGACCGGCTTC
CAGAACTGGAAGCCAGGCCAGCCAGACGACTGGCAGGGGCACGGGCTGGGTGGAGGCGAG
GACTGTGCTCACTTCCATCCAGACGGCAGGTGGAATGACGACGTCTGCCAGAGGCCCTAC
CACTGGGTCTGCGAGGCTGGCCTGGGTCAGACCAGCCAGGAGAGTCACTGA
Protein Properties
Number of Residues 316
Molecular Weight 35445.7
Theoretical pI 5.99
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["40-60"]
Protein Sequence
>C-type lectin domain family 10 member A
MTRTYENFQYLENKVKVQGFKNGPLPLQSLLQRLCSGPCHLLLSLGLGLLLLVIICVVGF
QNSKFQRDLVTLRTDFSNFTSNTVAEIQALTSQGSSLEETIASLKAEVEGFKQERQAGVS
ELQEHTTQKAHLGHCPHCPSVCVPVHSEMLLRVQQLVQDLKKLTCQVATLNNNASTEGTC
CPVNWVEHQDSCYWFSHSGMSWAEAEKYCQLKNAHLVVINSREEQNFVQKYLGSAYTWMG
LSDPEGAWKWVDGTDYATGFQNWKPGQPDDWQGHGLGGGEDCAHFHPDGRWNDDVCQRPY
HWVCEAGLGQTSQESH
GenBank ID Protein 33667103
UniProtKB/Swiss-Prot ID Q8IUN9
UniProtKB/Swiss-Prot Entry Name CLC10_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_182906.2
GeneCard ID CLEC10A
GenAtlas ID CLEC10A
HGNC ID HGNC:16916
References
General References Not Available