Identification |
HMDB Protein ID
| CDBP02802 |
Secondary Accession Numbers
| Not Available |
Name
| C-type lectin domain family 10 member A |
Description
| Not Available |
Synonyms
|
- C-type lectin superfamily member 14
- CD301 antigen
- Macrophage lectin 2
|
Gene Name
| CLEC10A |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in sugar binding |
Specific Function
| Probable role in regulating adaptive and innate immune responses. Binds in a calcium-dependent manner to terminal galactose and N-acetylgalactosamine units, linked to serine or threonine. These sugar moieties are known as Tn-Ag and are expressed in a variety of carcinoma cells |
GO Classification
|
Component |
membrane |
cell part |
Function |
binding |
carbohydrate binding |
sugar binding |
|
Cellular Location
|
- Membrane
- Single-pass type II membrane protein (Probable)
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:1 |
Locus
| 17p13.1 |
SNPs
| CLEC10A |
Gene Sequence
|
>951 bp
ATGACAAGGACGTATGAAAACTTCCAGTACTTGGAGAATAAGGTGAAAGTCCAGGGGTTT
AAAAATGGGCCACTTCCTCTCCAGTCCCTCCTGCAGCGTCTCTGCTCTGGGCCCTGCCAT
CTCCTGCTGTCCCTGGGCCTCGGCCTCCTGCTGCTGGTCATCATCTGTGTGGTTGGATTC
CAAAATTCCAAATTTCAGAGGGACCTGGTGACCCTGAGAACAGATTTTAGCAACTTCACC
TCAAACACTGTGGCGGAGATCCAGGCACTGACTTCCCAGGGCAGCAGCTTGGAAGAAACG
ATAGCATCTCTGAAAGCTGAGGTGGAGGGTTTCAAGCAGGAACGGCAGGCAGGGGTATCT
GAGCTCCAGGAACACACTACGCAGAAGGCACACCTAGGCCACTGTCCCCACTGCCCATCT
GTGTGTGTCCCAGTTCATTCTGAAATGCTCCTGCGAGTCCAGCAGCTGGTGCAAGACCTG
AAGAAACTGACCTGCCAGGTGGCTACTCTCAACAACAATGCCTCCACTGAAGGGACCTGC
TGCCCTGTCAACTGGGTGGAGCACCAAGACAGCTGCTACTGGTTCTCTCACTCTGGGATG
TCCTGGGCCGAGGCTGAGAAGTACTGCCAGCTGAAGAACGCCCACCTGGTGGTCATCAAC
TCCAGGGAGGAGCAGAATTTTGTCCAGAAATATCTAGGCTCCGCATACACCTGGATGGGC
CTCAGTGACCCTGAAGGAGCCTGGAAGTGGGTGGATGGAACAGACTATGCGACCGGCTTC
CAGAACTGGAAGCCAGGCCAGCCAGACGACTGGCAGGGGCACGGGCTGGGTGGAGGCGAG
GACTGTGCTCACTTCCATCCAGACGGCAGGTGGAATGACGACGTCTGCCAGAGGCCCTAC
CACTGGGTCTGCGAGGCTGGCCTGGGTCAGACCAGCCAGGAGAGTCACTGA
|
Protein Properties |
Number of Residues
| 316 |
Molecular Weight
| 35445.7 |
Theoretical pI
| 5.99 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>C-type lectin domain family 10 member A
MTRTYENFQYLENKVKVQGFKNGPLPLQSLLQRLCSGPCHLLLSLGLGLLLLVIICVVGF
QNSKFQRDLVTLRTDFSNFTSNTVAEIQALTSQGSSLEETIASLKAEVEGFKQERQAGVS
ELQEHTTQKAHLGHCPHCPSVCVPVHSEMLLRVQQLVQDLKKLTCQVATLNNNASTEGTC
CPVNWVEHQDSCYWFSHSGMSWAEAEKYCQLKNAHLVVINSREEQNFVQKYLGSAYTWMG
LSDPEGAWKWVDGTDYATGFQNWKPGQPDDWQGHGLGGGEDCAHFHPDGRWNDDVCQRPY
HWVCEAGLGQTSQESH
|
External Links |
GenBank ID Protein
| 33667103 |
UniProtKB/Swiss-Prot ID
| Q8IUN9 |
UniProtKB/Swiss-Prot Entry Name
| CLC10_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| NM_182906.2 |
GeneCard ID
| CLEC10A |
GenAtlas ID
| CLEC10A |
HGNC ID
| HGNC:16916 |
References |
General References
| Not Available |