| Identification |
|---|
| HMDB Protein ID
| CDBP02796 |
| Secondary Accession Numbers
| Not Available |
| Name
| Carcinoembryonic antigen-related cell adhesion molecule 3 |
| Description
| Not Available |
| Synonyms
|
- CD66d antigen
- Carcinoembryonic antigen CGM1
|
| Gene Name
| CEACAM3 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Major granulocyte receptor mediating recognition and efficient opsonin-independent phagocytosis of CEACAM-binding microorganisms, including Neissiria, Moxarella and Haemophilus species, thus playing an important role in the clearance of pathogens by the innate immune system. Responsible for RAC1 stimulation in the course of pathogen phagocytosis |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Membrane
- Single-pass type I membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 19q13.2 |
| SNPs
| CEACAM3 |
| Gene Sequence
|
>759 bp
ATGGGGCCCCCCTCAGCCTCTCCCCACAGAGAATGCATCCCCTGGCAGGGGCTTCTGCTC
ACAGCCTCACTTCTAAACTTCTGGAACCCGCCCACCACTGCCAAGCTCACTATTGAATCC
ATGCCGCTCAGTGTCGCAGAGGGGAAGGAGGTGCTTCTACTTGTCCACAATCTGCCCCAG
CATCTTTTTGGCTACAGCTGGTACAAAGGGGAAAGAGTGGATGGCAACAGTCTAATTGTA
GGATATGTAATAGGAACTCAACAAGCTACCCCAGGGGCCGCATACAGCGGTCGAGAGACA
ATATACACCAATGCATCCCTGCTGATCCAGAATGTCACCCAGAATGACATAGGATTCTAC
ACCCTACAAGTCATAAAGTCAGATCTTGTGAATGAAGAAGCAACTGGACAGTTCCATGTA
TACCAAGAAAATGCCCCAGGCCTTCCTGTGGGGGCCGTCGCCGGCATCGTGACCGGGGTC
CTGGTCGGAGTGGCGCTGGTGGCCGCGCTGGTGTGTTTCCTGCTCCTTGCCAAAACTGGA
AGAACCAGCATCCAGCGTGACCTCAAGGAGCAGCAGCCCCAAGCCCTTGCCCCTGGCCGT
GGTCCCTCCCACAGCTCTGCCTTCTCGATGTCCCCTCTCTCCACTGCCCAGGCCCCCCTA
CCCAACCCCAGGACAGCAGCTTCCATCTATGAGGAATTGCTAAAACATGACACAAACATT
TACTGCCGGATGGACCACAAAGCAGAAGTGGCTTCTTAG
|
| Protein Properties |
|---|
| Number of Residues
| 252 |
| Molecular Weight
| 27090.7 |
| Theoretical pI
| 6.63 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Carcinoembryonic antigen-related cell adhesion molecule 3
MGPPSASPHRECIPWQGLLLTASLLNFWNPPTTAKLTIESMPLSVAEGKEVLLLVHNLPQ
HLFGYSWYKGERVDGNSLIVGYVIGTQQATPGAAYSGRETIYTNASLLIQNVTQNDIGFY
TLQVIKSDLVNEEATGQFHVYQENAPGLPVGAVAGIVTGVLVGVALVAALVCFLLLAKTG
RTSIQRDLKEQQPQALAPGRGPSHSSAFSMSPLSTAQAPLPNPRTAASIYEELLKHDTNI
YCRMDHKAEVAS
|
| External Links |
|---|
| GenBank ID Protein
| 121114300 |
| UniProtKB/Swiss-Prot ID
| P40198 |
| UniProtKB/Swiss-Prot Entry Name
| CEAM3_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_001815.2 |
| GeneCard ID
| CEACAM3 |
| GenAtlas ID
| CEACAM3 |
| HGNC ID
| HGNC:1815 |
| References |
|---|
| General References
| Not Available |